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WO2001032864A3 - Gpcr-kd5 polypeptides and dna sequences thereof - Google Patents

Gpcr-kd5 polypeptides and dna sequences thereof Download PDF

Info

Publication number
WO2001032864A3
WO2001032864A3 PCT/EP2000/010564 EP0010564W WO0132864A3 WO 2001032864 A3 WO2001032864 A3 WO 2001032864A3 EP 0010564 W EP0010564 W EP 0010564W WO 0132864 A3 WO0132864 A3 WO 0132864A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
gpcr
dna sequences
polynucleotides
disclosed
Prior art date
Application number
PCT/EP2000/010564
Other languages
French (fr)
Other versions
WO2001032864A2 (en
Inventor
Klaus Duecker
Original Assignee
Merck Patent Gmbh
Klaus Duecker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh, Klaus Duecker filed Critical Merck Patent Gmbh
Priority to JP2001535546A priority Critical patent/JP2003513629A/en
Priority to CA002388308A priority patent/CA2388308A1/en
Priority to EP00983092A priority patent/EP1226250A2/en
Publication of WO2001032864A2 publication Critical patent/WO2001032864A2/en
Publication of WO2001032864A3 publication Critical patent/WO2001032864A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

GPCR_KD5 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing GPCR_KD5 polypeptides and polynucleotides in diagnostic assays.
PCT/EP2000/010564 1999-11-03 2000-10-26 Gpcr-kd5 polypeptides and dna sequences thereof WO2001032864A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2001535546A JP2003513629A (en) 1999-11-03 2000-10-26 Novel GPCR_KD5 polypeptide and its DNA sequence
CA002388308A CA2388308A1 (en) 1999-11-03 2000-10-26 Gpcr-kd5 polypeptides and dna sequences thereof
EP00983092A EP1226250A2 (en) 1999-11-03 2000-10-26 Gpcr-kd5 polypeptides and dna sequences thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99121786.0 1999-11-03
EP99121786 1999-11-03

Publications (2)

Publication Number Publication Date
WO2001032864A2 WO2001032864A2 (en) 2001-05-10
WO2001032864A3 true WO2001032864A3 (en) 2001-12-06

Family

ID=8239324

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/010564 WO2001032864A2 (en) 1999-11-03 2000-10-26 Gpcr-kd5 polypeptides and dna sequences thereof

Country Status (4)

Country Link
EP (1) EP1226250A2 (en)
JP (1) JP2003513629A (en)
CA (1) CA2388308A1 (en)
WO (1) WO2001032864A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
ATE348162T1 (en) * 2000-05-18 2007-01-15 Bayer Healthcare Ag REGULATION OF A HUMAN DOPAMINE-LIKE G-PROTEIN COUPLED RECEPTOR.
US20030180813A1 (en) 2000-12-01 2003-09-25 Takahide Ohishi Method of screening remedy for diabetes
US7083933B1 (en) 2003-05-09 2006-08-01 Prosidion Limited Methods for identification of modulators of OSGPR116 activity
EP2197873B1 (en) 2007-09-20 2014-07-16 Irm Llc Compounds and compositions as modulators of gpr119 activity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2000050562A2 (en) * 1999-02-22 2000-08-31 Synaptic Pharmaceutical Corporation Dna encoding snorf25 receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000031258A2 (en) * 1998-11-20 2000-06-02 Arena Pharmaceuticals, Inc. Human orphan g protein-coupled receptors
WO2000050562A2 (en) * 1999-02-22 2000-08-31 Synaptic Pharmaceutical Corporation Dna encoding snorf25 receptor

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 1 January 1900 (1900-01-01), LEDENT C, ET AL: "ADENOSINE A2A RECEPTOR. ADORA2A", XP002166397, Database accession no. Q60613 *
DATABASE EMBL 1 January 1900 (1900-01-01), PEARCE A: "HUMAN DNA SEQUENCE FROM CLONE 20I3 ON CHROMOSOME XQ25-26 CONTAINS A GENE FOR BRAIN MITOCHONDRIAL CARRIER PROTEIN-1 (BMCP1), ESTS, STSS, GSSS AND A CPG ISLAND", XP002166396, Database accession no. AL035423 *
LEDENT, C. ET AL.: "Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor", NATURE, vol. 388, no. 6643, 14 August 1997 (1997-08-14), pages 674 - 678, XP000993254 *

Also Published As

Publication number Publication date
WO2001032864A2 (en) 2001-05-10
JP2003513629A (en) 2003-04-15
CA2388308A1 (en) 2001-05-10
EP1226250A2 (en) 2002-07-31

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