WO2001029032A8 - Nouveaux procedes - Google Patents
Nouveaux procedesInfo
- Publication number
- WO2001029032A8 WO2001029032A8 PCT/GB2000/004066 GB0004066W WO0129032A8 WO 2001029032 A8 WO2001029032 A8 WO 2001029032A8 GB 0004066 W GB0004066 W GB 0004066W WO 0129032 A8 WO0129032 A8 WO 0129032A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- paroxetine
- preparation
- arecoline
- starting
- disclosed
- Prior art date
Links
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title abstract 2
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002296 paroxetine Drugs 0.000 title abstract 2
- HJJPJSXJAXAIPN-UHFFFAOYSA-N arecoline Chemical compound COC(=O)C1=CCCN(C)C1 HJJPJSXJAXAIPN-UHFFFAOYSA-N 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU10385/01A AU1038501A (en) | 1999-10-20 | 2000-10-20 | Novel processes |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9924882.5A GB9924882D0 (en) | 1999-10-20 | 1999-10-20 | Novel process |
GB9924882.5 | 1999-10-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001029032A1 WO2001029032A1 (fr) | 2001-04-26 |
WO2001029032A8 true WO2001029032A8 (fr) | 2001-05-25 |
Family
ID=10863097
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2000/004066 WO2001029032A1 (fr) | 1999-10-20 | 2000-10-20 | Nouveaux procedes |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1038501A (fr) |
GB (1) | GB9924882D0 (fr) |
WO (1) | WO2001029032A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9930577D0 (en) * | 1999-12-23 | 2000-02-16 | Smithkline Beecham Plc | Novel process |
US7138523B2 (en) | 2002-05-16 | 2006-11-21 | Apotex Pharmachem Inc. | Preparation of 4-(4-fluorophenyl)-N-alkylnipecotinate esters, 4-(4-fluorophenyl)-N-arylnipecotinate esters and 4-(4-fluorophenyl)-N-aralkylnipecotinate esters |
WO2004043921A1 (fr) * | 2002-11-11 | 2004-05-27 | Natco Pharma Limited | Nouveau procede de preparation de 4-aryl-3-hydroxymethyl-1-methylpiperidines |
WO2005063707A1 (fr) * | 2003-12-26 | 2005-07-14 | Natco Pharma Limited | Procede enantiospecifique permettant de preparer un intermediaire de paroxetine |
WO2007015262A2 (fr) * | 2005-04-25 | 2007-02-08 | Sun Pharmaceutical Industries Limited | Procede pour preparer de la (-)-trans-4-(4-fluorophenyl)-3-[[3,4-(methylenedioxy)phenoxy]methyl]piperidine |
CN101205211B (zh) * | 2006-12-19 | 2011-12-14 | 北京德众万全药物技术开发有限公司 | 一种盐酸帕罗西汀重要中间体的制备方法 |
CN117964546B (zh) * | 2024-03-28 | 2024-06-11 | 成都硕德药业有限公司 | 一种尼拉帕利中间体的制备方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
EP0223334B1 (fr) * | 1985-08-10 | 1991-07-10 | Beecham Group Plc | Procédé de préparation d'aryl-pipéridine-carbinols |
GB8520154D0 (en) * | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
FR2702220B1 (fr) * | 1993-03-03 | 1995-05-12 | Synthelabo | Dédoublement enzymatique de dérivés de 4-alkyl-2-pipéridine-carboxylate et utilisation des composés obtenus, comme intermédiaires de synthèse. |
EP0812827B1 (fr) * | 1996-06-13 | 2009-09-02 | Sumitomo Chemical Company, Limited | Dérivés de pipéridine comme intermédiaire pour la production de paroxétine et procédé pour leur préparation |
WO1998002556A2 (fr) * | 1996-07-15 | 1998-01-22 | Smithkline Beecham Plc | Criblage et utilisation d'esterase pour dedoublement stereospecifique |
CA2284732C (fr) * | 1997-04-07 | 2008-06-17 | Georgetown University | Analogues de cocaine |
CA2346537A1 (fr) * | 1998-10-07 | 2000-04-13 | Gian Luca Araldi | Heterocycles monomeres et dimeres et leurs utilisations therapeutiques |
-
1999
- 1999-10-20 GB GBGB9924882.5A patent/GB9924882D0/en not_active Ceased
-
2000
- 2000-10-20 AU AU10385/01A patent/AU1038501A/en not_active Abandoned
- 2000-10-20 WO PCT/GB2000/004066 patent/WO2001029032A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
AU1038501A (en) | 2001-04-30 |
WO2001029032A1 (fr) | 2001-04-26 |
GB9924882D0 (en) | 1999-12-22 |
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