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WO2001021840A3 - Indexing populations - Google Patents

Indexing populations Download PDF

Info

Publication number
WO2001021840A3
WO2001021840A3 PCT/US2000/026207 US0026207W WO0121840A3 WO 2001021840 A3 WO2001021840 A3 WO 2001021840A3 US 0026207 W US0026207 W US 0026207W WO 0121840 A3 WO0121840 A3 WO 0121840A3
Authority
WO
WIPO (PCT)
Prior art keywords
indexing
methods
relates
populations
regards
Prior art date
Application number
PCT/US2000/026207
Other languages
French (fr)
Other versions
WO2001021840A2 (en
Inventor
Richard Guilfoyle
Original Assignee
Gene Logic Inc
Richard Guilfoyle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gene Logic Inc, Richard Guilfoyle filed Critical Gene Logic Inc
Priority to AU77124/00A priority Critical patent/AU7712400A/en
Publication of WO2001021840A2 publication Critical patent/WO2001021840A2/en
Publication of WO2001021840A3 publication Critical patent/WO2001021840A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855—Ligating adaptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to method and devices for indexing populations, among other things. Particular embodiments relate to methods for indexing population that can be carried out in homogeneous media, particularly methods in which indexing reactions can be carried out in homogeneous media and the products of the reactions can be determined without physically separating the products from the reaction. In these and other regards the invention further relates to methods and devices for indexing using real time monitoring and determinations based on reaction kinetics. In another further respect in these and other regards the invention relates to multiplexed indexing. And, in a still further specific in all these regards the invention relates to methods and devices for indexing a substantial fraction of all sub-populations of a given type. Specific embodiments relate to polynucleotides to expression profiling and to strand displacement indexing and reagent for strand displacement indexing.
PCT/US2000/026207 1999-09-23 2000-09-25 Indexing populations WO2001021840A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU77124/00A AU7712400A (en) 1999-09-23 2000-09-25 Indexing populations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15548899P 1999-09-23 1999-09-23
US60/155,488 1999-09-23

Publications (2)

Publication Number Publication Date
WO2001021840A2 WO2001021840A2 (en) 2001-03-29
WO2001021840A3 true WO2001021840A3 (en) 2001-12-06

Family

ID=22555635

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/026207 WO2001021840A2 (en) 1999-09-23 2000-09-25 Indexing populations

Country Status (2)

Country Link
AU (1) AU7712400A (en)
WO (1) WO2001021840A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2292788B1 (en) 2005-06-23 2012-05-09 Keygene N.V. Strategies for high throughput identification and detection of polymorphisms
ATE453728T1 (en) 2005-09-29 2010-01-15 Keygene Nv HIGH-THROUGHPUT SCREENING OF MUTAGENIZED POPULATIONS
US10316364B2 (en) 2005-09-29 2019-06-11 Keygene N.V. Method for identifying the source of an amplicon
EP3404114B1 (en) * 2005-12-22 2021-05-05 Keygene N.V. Method for high-throughput aflp-based polymorphism detection
ES2645661T3 (en) 2006-04-04 2017-12-07 Keygene N.V. High performance detection of molecular markers based on restriction fragments

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0735144A1 (en) * 1995-03-28 1996-10-02 Research Development Corporation Of Japan Method for molecular indexing categorising of expressed genes using restriction enzymes
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
WO1997031256A2 (en) * 1996-02-09 1997-08-28 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO1997042345A1 (en) * 1996-05-04 1997-11-13 Zeneca Limited Method for detecting a nucleic acid base sequence
WO1998010095A1 (en) * 1996-09-05 1998-03-12 Brax Genomics Limited Characterising dna
WO1998040518A2 (en) * 1997-03-11 1998-09-17 Wisconsin Alumni Research Foundation Nucleic acid indexing
WO1999002727A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Categorising nucleic acid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0735144A1 (en) * 1995-03-28 1996-10-02 Research Development Corporation Of Japan Method for molecular indexing categorising of expressed genes using restriction enzymes
WO1997014028A2 (en) * 1995-10-11 1997-04-17 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and method
WO1997031256A2 (en) * 1996-02-09 1997-08-28 Cornell Research Foundation, Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
WO1997042345A1 (en) * 1996-05-04 1997-11-13 Zeneca Limited Method for detecting a nucleic acid base sequence
WO1998010095A1 (en) * 1996-09-05 1998-03-12 Brax Genomics Limited Characterising dna
WO1998040518A2 (en) * 1997-03-11 1998-09-17 Wisconsin Alumni Research Foundation Nucleic acid indexing
WO1999002727A1 (en) * 1997-07-11 1999-01-21 Brax Group Limited Categorising nucleic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
UNRAU P ET AL: "NON-CLONING AMPLIFICATION OF SPECIFIC DNA FRAGMENTS FROM WHOLE GENOMIC DNA DIGEST USING DNA 'INDEXERS'", GENE, 1994, XP002054436 *

Also Published As

Publication number Publication date
AU7712400A (en) 2001-04-24
WO2001021840A2 (en) 2001-03-29

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