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WO2001018030A3 - Small peptides having potent anti-angiogenic activity - Google Patents

Small peptides having potent anti-angiogenic activity Download PDF

Info

Publication number
WO2001018030A3
WO2001018030A3 PCT/SG2000/000131 SG0000131W WO0118030A3 WO 2001018030 A3 WO2001018030 A3 WO 2001018030A3 SG 0000131 W SG0000131 W SG 0000131W WO 0118030 A3 WO0118030 A3 WO 0118030A3
Authority
WO
WIPO (PCT)
Prior art keywords
potent anti
angiogenic activity
small peptides
peptides
prevention
Prior art date
Application number
PCT/SG2000/000131
Other languages
French (fr)
Other versions
WO2001018030A2 (en
Inventor
Rowen Ge
R Manjunatha Kini
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Publication of WO2001018030A2 publication Critical patent/WO2001018030A2/en
Publication of WO2001018030A3 publication Critical patent/WO2001018030A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides peptides having potent anti-angiogenic activity. The peptides can be administered as pharmaceutical compositions for prevention or treatment of undesired angiogenesis, for instance for prevention of tumor metastasis or inhibition of primary tumor growth.
PCT/SG2000/000131 1999-09-03 2000-09-01 Small peptides having potent anti-angiogenic activity WO2001018030A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG9904310-1 1999-09-03
SG9904310A SG87828A1 (en) 1999-09-03 1999-09-03 Small peptides having potent anti-angiogenic activity

Publications (2)

Publication Number Publication Date
WO2001018030A2 WO2001018030A2 (en) 2001-03-15
WO2001018030A3 true WO2001018030A3 (en) 2001-09-27

Family

ID=20430423

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SG2000/000131 WO2001018030A2 (en) 1999-09-03 2000-09-01 Small peptides having potent anti-angiogenic activity

Country Status (2)

Country Link
SG (1) SG87828A1 (en)
WO (1) WO2001018030A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20060625A1 (en) * 2006-03-31 2007-10-01 Istituto Naz Per La Ricerca ANTIANGIOGENIC PEPTIDE AND ITS THERAPEUTIC USES
US20150218213A1 (en) * 2012-09-04 2015-08-06 Università Degli Studi Di Torino Inhibitors of alpha6 integrin/e-cadherin complex
JP2020532586A (en) * 2017-08-31 2020-11-12 シンガポール ヘルス サービシーズ プライベート リミテッド ANGIO-3 for the treatment of retinal vascular disease

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015666A1 (en) * 1995-10-23 1997-05-01 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods
WO1997041824A2 (en) * 1996-05-03 1997-11-13 Abbott Laboratories Antiangiogenic peptides derived from plasminogen
WO2000026368A2 (en) * 1998-10-30 2000-05-11 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997015666A1 (en) * 1995-10-23 1997-05-01 The Children's Medical Center Corporation Therapeutic antiangiogenic compositions and methods
WO1997041824A2 (en) * 1996-05-03 1997-11-13 Abbott Laboratories Antiangiogenic peptides derived from plasminogen
US6057122A (en) * 1996-05-03 2000-05-02 Abbott Laboratories Antiangiogenic peptides polynucleotides encoding same and methods for inhibiting angiogenesis
WO2000026368A2 (en) * 1998-10-30 2000-05-11 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions

Also Published As

Publication number Publication date
WO2001018030A2 (en) 2001-03-15
SG87828A1 (en) 2002-04-16

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