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WO2001090150A3 - G protein-coupled receptors from human clone '26908' and uses thereof - Google Patents

G protein-coupled receptors from human clone '26908' and uses thereof Download PDF

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Publication number
WO2001090150A3
WO2001090150A3 PCT/US2001/016657 US0116657W WO0190150A3 WO 2001090150 A3 WO2001090150 A3 WO 2001090150A3 US 0116657 W US0116657 W US 0116657W WO 0190150 A3 WO0190150 A3 WO 0190150A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
protein
expression vectors
coupled receptors
Prior art date
Application number
PCT/US2001/016657
Other languages
French (fr)
Other versions
WO2001090150A2 (en
Inventor
Maria Alexandra Glucksmann
Original Assignee
Millennium Pharm Inc
Maria Alexandra Glucksmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria Alexandra Glucksmann filed Critical Millennium Pharm Inc
Priority to AU2001263379A priority Critical patent/AU2001263379A1/en
Priority to EP01937666A priority patent/EP1309623A2/en
Publication of WO2001090150A2 publication Critical patent/WO2001090150A2/en
Publication of WO2001090150A3 publication Critical patent/WO2001090150A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 26908 nucleic acid molecules, which encode novel G-protein coupled receptor family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 26908 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 26908 gene has been introduced or disrupted. The invention still further provides isolated 26908 proteins, fusion proteins, antigenic peptides and anti-26908 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/016657 2000-05-22 2001-05-22 G protein-coupled receptors from human clone '26908' and uses thereof WO2001090150A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001263379A AU2001263379A1 (en) 2000-05-22 2001-05-22 G protein-coupled receptors from human clone "26908" and uses thereof
EP01937666A EP1309623A2 (en) 2000-05-22 2001-05-22 G protein-coupled receptors from human clone "26908" and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20601900P 2000-05-22 2000-05-22
US60/206,019 2000-05-22

Publications (2)

Publication Number Publication Date
WO2001090150A2 WO2001090150A2 (en) 2001-11-29
WO2001090150A3 true WO2001090150A3 (en) 2002-10-03

Family

ID=22764647

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016657 WO2001090150A2 (en) 2000-05-22 2001-05-22 G protein-coupled receptors from human clone '26908' and uses thereof

Country Status (4)

Country Link
US (1) US20020039762A1 (en)
EP (1) EP1309623A2 (en)
AU (1) AU2001263379A1 (en)
WO (1) WO2001090150A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003052096A1 (en) * 2001-12-14 2003-06-26 Takeda Chemical Industries, Ltd. Mtehod of analyzing gene expression
FR2945042B1 (en) * 2009-04-30 2016-05-13 Immunosearch NOVEL POLYPEPTIDES FOR THE IN VITRO ASSESSMENT OF THE SENSITIZING POTENTIAL OF A TEST COMPOUND

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891720A (en) * 1997-04-17 1999-04-06 Millennium Pharmaceuticals, Inc. Isolated DNA encoding a novel human G-protein coupled receptor
WO1999063087A1 (en) * 1998-06-02 1999-12-09 Millennium Pharmaceuticals, Inc. G-protein coupled receptor, named 2871 receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001090189A2 (en) * 2000-05-24 2001-11-29 Akzo Nobel N.V. G-protein coupled receptor org3.

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891720A (en) * 1997-04-17 1999-04-06 Millennium Pharmaceuticals, Inc. Isolated DNA encoding a novel human G-protein coupled receptor
WO1999063087A1 (en) * 1998-06-02 1999-12-09 Millennium Pharmaceuticals, Inc. G-protein coupled receptor, named 2871 receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001090189A2 (en) * 2000-05-24 2001-11-29 Akzo Nobel N.V. G-protein coupled receptor org3.

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 15 February 2001 (2001-02-15), DOE JOINT GENOME INSTITUTE: "Homo sapiens chromosome 5 clone CTD-2042J7", XP002197028, Database accession no. AC090068 *
DATABASE EMBL DATABASE [online] 8 February 2000 (2000-02-08), BIRREN B ET AL.: "Mus musculus chromosome X clone RP23-157B8", XP002197027, Database accession no. AC022773 *
MARCHESE ET AL: "Discovery of three novel orphan G-protein-coupled receptors", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 56, no. 1, 15 February 1999 (1999-02-15), pages 12 - 21, XP002108432, ISSN: 0888-7543 *
PELLICCIARI R ET AL: "METABOTROPIC G-PROTEIN-COUPLED GLUTAMATE RECEPTORS AS THERAPEUTIC TARGETS", CURRENT OPINION IN CHEMICAL BIOLOGY, CURRENT BIOLOGY LTD, LONDON, GB, vol. 3, no. 4, 1999, pages 433 - 440, XP000886873, ISSN: 1367-5931 *
SONNHAMMER E L L ET AL: "PFAM: A COMPREHENSIVE DATABASE OF PROTEIN DOMAIN FAMILIES BASED ON SEED ALIGNMENTS", PROTEINS, ALAN R. LISS, US, vol. 28, 1997, pages 405 - 420, XP002929239, ISSN: 0887-3585 *
STADEL J M ET AL: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 18, no. 11, 1 November 1997 (1997-11-01), pages 430 - 437, XP004099345, ISSN: 0165-6147 *
WILSON S ET AL: "ORPHAN G-PROTEIN-COUPLED RECEPTORS: THE NEXT GENERATION OF DRUG TARGETS?", BRITISH JOURNAL OF PHARMACOLOGY, BASINGSTOKE, HANTS, GB, vol. 125, no. 7, December 1998 (1998-12-01), pages 1387 - 1392, XP001010584, ISSN: 0007-1188 *

Also Published As

Publication number Publication date
AU2001263379A1 (en) 2001-12-03
WO2001090150A2 (en) 2001-11-29
US20020039762A1 (en) 2002-04-04
EP1309623A2 (en) 2003-05-14

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