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WO2001089495A3 - Compositions antibiotiques destinees au traitement des yeux, oreilles et nez - Google Patents

Compositions antibiotiques destinees au traitement des yeux, oreilles et nez Download PDF

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Publication number
WO2001089495A3
WO2001089495A3 PCT/US2001/016107 US0116107W WO0189495A3 WO 2001089495 A3 WO2001089495 A3 WO 2001089495A3 US 0116107 W US0116107 W US 0116107W WO 0189495 A3 WO0189495 A3 WO 0189495A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
treatment
compositions containing
nose
ear
Prior art date
Application number
PCT/US2001/016107
Other languages
English (en)
Other versions
WO2001089495A2 (fr
Inventor
Gerald Cagle
Robert L Abshire
David W Stroman
Celeste H Mclean
Linda L Clark
John M Yanni
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Priority to AU2001261748A priority Critical patent/AU2001261748A1/en
Publication of WO2001089495A2 publication Critical patent/WO2001089495A2/fr
Publication of WO2001089495A3 publication Critical patent/WO2001089495A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des compositions ophtalmiques, otiques et nasales renfermant une nouvelle classe d'antibiotiques (par exemple, la moxifloxacine). Les compositions renferment également, de préférence, un ou plusieurs agents anti-inflammatoires et peuvent être utilisées pour traiter des affections ophtalmiques, otiques et nasales par l'application topique de celles-ci sur les tissus affectés. Les compositions et procédés selon l'invention sont particulièrement utiles dans le traitement d'infections liées à une otite externe aiguë et d'infections ophtalmiques pouvant être attribuées à une des deux espèces de Microbacterium récemment identifiées,Microbacterium otitidis et Microbacterium alconae. ou à ces deux espèces.
PCT/US2001/016107 2000-05-19 2001-05-17 Compositions antibiotiques destinees au traitement des yeux, oreilles et nez WO2001089495A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001261748A AU2001261748A1 (en) 2000-05-19 2001-05-17 Antibiotic compositions for treatment of the eye, ear and nose

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57726200A 2000-05-19 2000-05-19
US09/577,262 2000-05-19

Publications (2)

Publication Number Publication Date
WO2001089495A2 WO2001089495A2 (fr) 2001-11-29
WO2001089495A3 true WO2001089495A3 (fr) 2002-05-30

Family

ID=24307958

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016107 WO2001089495A2 (fr) 2000-05-19 2001-05-17 Compositions antibiotiques destinees au traitement des yeux, oreilles et nez

Country Status (2)

Country Link
AU (1) AU2001261748A1 (fr)
WO (1) WO2001089495A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6740664B2 (en) 1998-09-30 2004-05-25 Alcon, Inc. Methods for treating otic and ophthalmic infections
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
DE602005012107D1 (de) 2004-08-13 2009-02-12 Schering Plough Ltd Pharmazeutische formulierungen mit einem antibioti
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
CN101848701A (zh) * 2007-11-05 2010-09-29 博士伦公司 水不混溶性物质作为药物递送的运载体
KR20100090278A (ko) * 2007-11-27 2010-08-13 알콘 리서치, 리미티드 목시플록사신 하이드로클로라이드 및 덱사메타손 포스페이트를 함유하는 국소용 안과 또는 이과용 용액 제제

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480879A (en) * 1992-10-09 1996-01-02 Bayer Aktiengesellschaft Quinolonecarboxylic acids
WO2000018386A2 (fr) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480879A (en) * 1992-10-09 1996-01-02 Bayer Aktiengesellschaft Quinolonecarboxylic acids
WO2000018386A2 (fr) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Compositions antibiotiques pour le traitement des yeux, des oreilles et du nez

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
GOLDSTEIN, ELLIE J. C. ET AL: "Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates", ANTIMICROB. AGENTS CHEMOTHER. (1995), 39(5), 1097-100, XP001034766 *
GOLDSTEIN, ELLIE J. C. ET AL: "In vitro activity of Bay 12-8039, a new 8-methoxyquinolone, compared to the activities of 11 other oral antimicrobial agents against 390 aerobic and anaerobic bacteria isolated from human and animal bite wound skin and soft tissue infections in humans", ANTIMICROB. AGENTS CHEMOTHER. (1997), 41(7), 1552-1557, XP001034767 *
RUBINSTEIN, ETHAN: "Pharmacology - tissue distribution [of moxifloxacin]", INT. MOXIFLOXACIN SYMP., 1ST (2000), MEETING DATE 1999, 130-133. EDITOR(S): MANDELL, LIONEL. PUBLISHER: SPRINGER-VERLAG, BERLIN, GERMANY., XP001034999 *

Also Published As

Publication number Publication date
WO2001089495A2 (fr) 2001-11-29
AU2001261748A1 (en) 2001-12-03

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