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WO2001083553A3 - G protein-coupled receptors - Google Patents

G protein-coupled receptors Download PDF

Info

Publication number
WO2001083553A3
WO2001083553A3 PCT/US2001/014050 US0114050W WO0183553A3 WO 2001083553 A3 WO2001083553 A3 WO 2001083553A3 US 0114050 W US0114050 W US 0114050W WO 0183553 A3 WO0183553 A3 WO 0183553A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
ngpcr
coupled receptors
polypeptides
gene
Prior art date
Application number
PCT/US2001/014050
Other languages
French (fr)
Other versions
WO2001083553A2 (en
Inventor
Luis A Parodi
Peter Lind
Torsten Sejlitz
Original Assignee
Upjohn Co
Luis A Parodi
Peter Lind
Torsten Sejlitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co, Luis A Parodi, Peter Lind, Torsten Sejlitz filed Critical Upjohn Co
Priority to EP01932827A priority Critical patent/EP1278844A2/en
Priority to AU2001259322A priority patent/AU2001259322A1/en
Publication of WO2001083553A2 publication Critical patent/WO2001083553A2/en
Publication of WO2001083553A3 publication Critical patent/WO2001083553A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention provides a gene encoding a G protein-coupled receptor termed nGPCR-x; constructs and recombinant host cells incorporating the genes; the nGPCR-x polypeptides encoded by the gene; antibodies to the nGPCR-x polypeptides; and methods of making and using all of the foregoing.
PCT/US2001/014050 2000-05-03 2001-05-01 G protein-coupled receptors WO2001083553A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01932827A EP1278844A2 (en) 2000-05-03 2001-05-01 G protein-coupled receptors
AU2001259322A AU2001259322A1 (en) 2000-05-03 2001-05-01 G protein-coupled receptors

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US20154900P 2000-05-03 2000-05-03
US20163200P 2000-05-03 2000-05-03
US20155000P 2000-05-03 2000-05-03
US20155200P 2000-05-03 2000-05-03
US20155100P 2000-05-03 2000-05-03
US20163300P 2000-05-03 2000-05-03
US20197800P 2000-05-03 2000-05-03
US20154800P 2000-05-03 2000-05-03
US60/201,552 2000-05-03
US60/201,549 2000-05-03
US60/201,548 2000-05-03
US60/201,633 2000-05-03
US60/201,551 2000-05-03
US60/201,550 2000-05-03
US60/201,978 2000-05-03
US60/201,632 2000-05-03

Publications (2)

Publication Number Publication Date
WO2001083553A2 WO2001083553A2 (en) 2001-11-08
WO2001083553A3 true WO2001083553A3 (en) 2002-08-22

Family

ID=27575167

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014050 WO2001083553A2 (en) 2000-05-03 2001-05-01 G protein-coupled receptors

Country Status (3)

Country Link
EP (1) EP1278844A2 (en)
AU (1) AU2001259322A1 (en)
WO (1) WO2001083553A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6759508B2 (en) 2000-09-01 2004-07-06 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
CZ20023567A3 (en) * 2000-03-29 2003-11-12 Corixa Corporation Compounds and methods for therapy and diagnosis of lung carcinoma
AU2001281882A1 (en) * 2000-06-26 2002-01-08 Bayer Aktiengesellschaft Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor
JP2005514931A (en) * 2002-01-04 2005-05-26 メタボレックス インコーポレーティッド Nucleic acid encoding a G protein-coupled receptor involved in islet cell signaling
WO2005024057A1 (en) * 2003-09-10 2005-03-17 Galapagos Genomics N.V. Method of identifying a compound that changes the amyloid-beta precursor protein processing in a cell

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0867508A2 (en) * 1997-03-28 1998-09-30 Smithkline Beecham Corporation Olfactory receptor of the 7-transmembrane receptor family - OLRCC15 receptor
WO1999037679A1 (en) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Ligand receptors and uses therefor
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
WO2001057085A2 (en) * 2000-02-02 2001-08-09 Incyte Genomics, Inc. G-protein coupled receptors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0867508A2 (en) * 1997-03-28 1998-09-30 Smithkline Beecham Corporation Olfactory receptor of the 7-transmembrane receptor family - OLRCC15 receptor
WO1999037679A1 (en) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Ligand receptors and uses therefor
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
WO2001057085A2 (en) * 2000-02-02 2001-08-09 Incyte Genomics, Inc. G-protein coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HTG [online] EMBL; 1 September 1999 (1999-09-01), BIRREN ET AL.: "Homo sapiens chromosome 11, clone 107_B_13", XP002190937, retrieved from EBI accession no. AC009642 Database accession no. AC009642 *

Also Published As

Publication number Publication date
AU2001259322A1 (en) 2001-11-12
EP1278844A2 (en) 2003-01-29
WO2001083553A2 (en) 2001-11-08

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