WO2001081535A3 - A novel polypeptide, a human pax protein 9.9 and the polynucleotide encoding the polypeptide - Google Patents
A novel polypeptide, a human pax protein 9.9 and the polynucleotide encoding the polypeptide Download PDFInfo
- Publication number
- WO2001081535A3 WO2001081535A3 PCT/CN2001/000595 CN0100595W WO0181535A3 WO 2001081535 A3 WO2001081535 A3 WO 2001081535A3 CN 0100595 W CN0100595 W CN 0100595W WO 0181535 A3 WO0181535 A3 WO 0181535A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- polynucleotide encoding
- pax protein
- human pax
- novel
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention discloses a novel polypeptide, human Pax protein 9.9, the polynucleotide encoding the same and the method of production thereof by DNA recombinant techniques. Method of using the polypeptide for treating various diseases such as malignant tumors, hemopathy, HIV infection, immune diseases, and various inflammation and the like are also disclosed. Furthermore, the invention discloses the antagonists of the polypeptide and the effects thereof. The uses of the polynucleotide encoding the novel human Pax protein 9.9 is also disclosed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU73798/01A AU7379801A (en) | 2000-04-27 | 2001-04-23 | A novel polypeptide, a human pax protein 9.9 and the polynucleotide encoding thepolypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00115464 CN1320624A (en) | 2000-04-27 | 2000-04-27 | Polypeptide-human Pax protein 9.9 and polynucleotide for coding it |
| CN00115464.8 | 2000-04-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001081535A2 WO2001081535A2 (en) | 2001-11-01 |
| WO2001081535A3 true WO2001081535A3 (en) | 2002-03-14 |
Family
ID=4584910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000595 WO2001081535A2 (en) | 2000-04-27 | 2001-04-23 | A novel polypeptide, a human pax protein 9.9 and the polynucleotide encoding the polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1320624A (en) |
| AU (1) | AU7379801A (en) |
| WO (1) | WO2001081535A2 (en) |
-
2000
- 2000-04-27 CN CN 00115464 patent/CN1320624A/en active Pending
-
2001
- 2001-04-23 AU AU73798/01A patent/AU7379801A/en not_active Abandoned
- 2001-04-23 WO PCT/CN2001/000595 patent/WO2001081535A2/en active Application Filing
Non-Patent Citations (3)
| Title |
|---|
| B.W. SCHAFER ET AL.: "Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes", NUCLEIC ACIDS RES., vol. 22, no. 22, 11 November 1994 (1994-11-11), pages 4574 - 4582 * |
| M. GERARD ET AL.: "PAX-genes expression during human embryonic development, a preliminary report", C.R. ACAD. SCI. III, vol. 318, no. 1, January 1995 (1995-01-01), pages 57 - 66 * |
| P. SANYANUSIN ET AL.: "Genomic structure of the human PAX2 gene", GENOMICS, vol. 35, no. 1, 1 July 1996 (1996-07-01), pages 258 - 261 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1320624A (en) | 2001-11-07 |
| WO2001081535A2 (en) | 2001-11-01 |
| AU7379801A (en) | 2001-11-07 |
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