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WO2001076453A2 - Dispositif de pointage irm et procede de determination de la position et de l'orientation - Google Patents

Dispositif de pointage irm et procede de determination de la position et de l'orientation Download PDF

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Publication number
WO2001076453A2
WO2001076453A2 PCT/IL2001/000318 IL0100318W WO0176453A2 WO 2001076453 A2 WO2001076453 A2 WO 2001076453A2 IL 0100318 W IL0100318 W IL 0100318W WO 0176453 A2 WO0176453 A2 WO 0176453A2
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WO
WIPO (PCT)
Prior art keywords
magnetic resonance
samples
pointing device
responsive material
sample
Prior art date
Application number
PCT/IL2001/000318
Other languages
English (en)
Other versions
WO2001076453A3 (fr
Inventor
Avinoam Livni
Haim Rotem
Ruth Ben-Kish
Zvi Polunsky
Elyakim Bosak
Original Assignee
Odin Medical Technologies Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Odin Medical Technologies Ltd. filed Critical Odin Medical Technologies Ltd.
Priority to AU48725/01A priority Critical patent/AU4872501A/en
Publication of WO2001076453A2 publication Critical patent/WO2001076453A2/fr
Publication of WO2001076453A3 publication Critical patent/WO2001076453A3/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/374—NMR or MRI
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
    • A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI

Definitions

  • the present invention relates to magnetic resonance imaging. More particularly it relates to a device and method for determining the position and orientation of a tool using a pointing device for use in a magnetic resonance imaging apparatus.
  • MRI magnetic resonance imaging
  • Interventional, or inta- operative MRI (iMRI) allows surgeons to obtain a practically on-line image of the patient's body part under surgery, and receive immediate feedback on the outcome of the operation carried out during surgery.
  • Israel Pat. Appl. No. 119558 Korean et al. filed November 4, 1996, incorporated herein by reference, discloses a compact, transportable, intra operative MRI System, which includes a host computer coupled to a central electronics system which may be coupled to different MRI probes.
  • Compact MRI systems for performing local imaging of specific body parts or organs may use a hollow tube-like magnet assembly or other assemblies, such as two opposing magnets, such as described in US Patent No. 5,900,793 (Katznelson et al.), filed July 23, 1997 incorporated herein by reference.
  • US Patent No. 5,735,278 (Hoult et al.), filed March 15, 1996, disclosed an apparatus for use in surgical procedure comprising an operating table for receiving a patient for surgery and an MRI system f ⁇ obtaining images of a part of the patient as a series of time through the surgical procedure for analysis by the surgical team to allow monitoring the progress of the surgery.
  • the high field magnet and the operating table are shaped and arranged for posioning of the part of the patient into the magnetic field while the patient remains in place of the table and the magnet is mounted for movement between a first position spaced from the table and the patient thereon to allow the surgical team to carry outthe surgical procedure and a second position for applying the magnetic field to the part of the patient.
  • the table remains substantially stationary and only the magnet is moved to a position spaced from an adjacent end of the table to allow the surgical team to move around the adjacent end of table and to each side of the table to access the patient.
  • an intraoperative MRI system such as the ones discussed above, would comprise an MRI system, with a magnet, positioned over an operating table.
  • the magnet assembly is constructed so as to leave open spaces around the patient allowing the medical team to attend the patient.
  • Another solution was the introduction of a magnet probe that can be brought near the patient lying on the operating table to perform the imaging, and then retracted to clear the way for the medical staff to access the patient.
  • MRI in particularly is appealing for its outstanding ability of obtaining contrast images, differentiating between different tissue types and allowing be visualization and detection of pathologies.
  • MRI provides the medical staff with good contrast images that allow tte surgeons to locate malignant tissue and evaluate its dimensions.
  • a major difficulty encountered during a tumor removal procedure is related to the fact that although it is possible to perform known MRI sequences in order to acquire good contrast MRI images thus allowing differentiation between malignant and healthy tissue on the image acquired, it may not be possible to notice the difference on the operated tissue itself.
  • the surgeon can clearly see the tumor and its boundaries on the image, but is unableto distinguish the tumor from its surrounding healthy tissue in the patient. For that reason, to date, only about as much as 70% of a brain tumor is removed in a conventional brain surgery. This may lead to future aggravation in the patient's condition, s the tumor grows back, seriously affecting the patient's quality of life or even endangering his life. For that reason it is sought to provide means for aiding the medical staff in determining the exact location of a medical instrument used in operation vith reference to the image obtained using MRI apparatus. Furthermore it is desirable that such means enable determining the orientation of such instrument.
  • US Patent 5,271 ,400 (Dumoulin et al.), filed Apr. 1 , 1992, there is disclosed a tracking system to monitor the position and orientation of a device using magnetic resonance detection of a sample contained within a device.
  • the detectable device which can be a guide wire, a catheter, an endoscope, a laparoscope, a biopsy needle or a similar device, cortains an RF (radio frequency) coil and a magnetic resonance responsive sample.
  • the MR responsive sample When the device is subjected to an RF pulse, generated by an outside RF coil or by the RF coil of the device, the MR responsive sample resonates, and the RF coil of the device, which is a small coil, detects the MR response signal from the MR responsive sample.
  • the coordinates of the MR responsive sample are calculated, and its position is marked on the MRI image, so as to enable the beholder to determine the relative position of the device with respect to the conventional image. It is explained that it is a purpose of that invention to provide a method for tracking a device using MR examination without loss of signal due to lack of MR responsive material in the internal cavities of a subject.
  • US Patent 5,318,025 (Dumoulin et al.), filed Apr. 1 , 1992, there is disclosed a tracking system to monitor the position and orientation of a device using magnetic multiplexed resonance detection
  • the detectable device disclosed contains a number of RF coils (instead of just one as described in US Patent 5,271 ,400)
  • the inventors of US Patent 5,318,025 do not explicitly explain the reason for providing at least two RF coils, but it is understood that this allows determining linear orientation (as only one RF coil is provided in the device described in US Patent 5,271 ,400)
  • the tracking device disclosed in US Patent 5,318,025 (having three aligned and evenly spaced RF coils) does not facilitate obtaining information as to the directionality of the device, and that may be determined only by other independently acquired medical diagnostic devices, as is explained there
  • US Patent 5,916,162 (Snelten et al ) it is disclosed an invasive device which is intended to cooperate with an MRI appaatus
  • the device is provided with an RF coil situated near the distal part of the invasive device
  • the RF coil is used to visualize the position of a distal end of the invasive device, introduced into an object, in an image of the object
  • the invasive device is provided with a hollow carrier
  • the electric connection extends through said carrier, which is provided with an electrically conductive shield with an additional resistance
  • the mvasive device disclosed in Snelten's patent is in fact a catheter for insertion into a blood vessel of a patient
  • the present invention it is suggested to provide a magnetic resonance detectable medical instrument to facilitate the use of that instrument during an intraoperative magnetic resonance imaging of the patient's body part or organ which is undergoes surgery
  • the pointing device may be also incorporated in a medical instrument so as to allow the medical staff to determine via the employment of an intraoperative MRI apparatus the position and orientation of the medical instrument with respect to the patient's part or organ being imaged
  • a pointing device to be used in cooperation with a magnetic resonance imaging apparatus, said device comprising a member of a predetermined shape, at least one sample of magnetic resonance responsive material placed within said member in a predetermined position, said sample geometrically arranged to have a distinct directionality, whereby when said device is introduced into said magnetic resonance imaging apparatus image region, the position sample may be obtained and marked on an image of said target
  • said member comprises a tube
  • said sample of magnetic resonance responsive material comprises water or gadolinium or nickel chloride solution provided in void of distinct shape within said member
  • said sample of magnetic resonance responsive material is provided in the shape of a cone
  • said sample of magnetic resonance responsive material is provided in the shape of a disc
  • said device comprises a plurality of samples of magnetic resonance responsive material, said plurality of samples of magnetic resonance responsive material geometrically arranged within said member to have a distinct directionality.
  • said device comprises three samples of magnetic resonance responsive material.
  • said three samples are each provided in a shape of a disc. Furthermore, in accordance with a preferred embodiment of the present invention, the gaps between said three samples are distinctly different whereby this aides in figuring the directionality of said device.
  • said device is further provided with an RF coil in the vicinity of said at least one sample of magnetic resonance responsive material, said RF coil adapted to allow it to be electrically connected to said magnetic resonance imaging apparatus.
  • said RF coil encircles said at least one sampleof magnetic resonance responsive material.
  • said RF coil is engulfed by said at least one sample of magnetic resonance responsive material.
  • a pointing device to be used in cooperation with a magnetic resonance imaging apparatus, said device comprising: a member of a predetermined shape; a plurality of samples of magnetic resonan ⁇ e responsive material placed within said member in a predetermined position, said samples geometrically arranged to have a distinct directionality; and RF coil provided in the vicinity of said plurality of samples of magnetic resonance responsive material adapted to allow it to be electrically connected to said magnetic resonance apparatus; whereby when said device is introduced into said magnetic resonance imaging apparatus image region the position of the sample may be obtained and marked on an image of said target.
  • said plurality of magnetic resonance responsive samples are from the same material but in different densities or concentrations. Furthermore, in accordance with a preferred embodiment of the present invention, said plurality of magnetic resonance responsive samples are provided with different sizes.
  • said RF coil is engulfed by said plurality of samples of magnetic resonance responsive material.
  • said member comprises a tube.
  • said plurality of samples of magnetic resonance responsive material comprises water or gadolinium or nickel chloride solution samples provided in voids of distinct shapes within said member.
  • said plurality of samples of magnetic resonance responsive material comprise three samples. Furthermore, in accordance with a preferred embodiment of the present invention, said three samples are each provided in a shape of a disc.
  • said RF coil comprises a plurality of RF coils, the number of which corresponds to the number of said plurality of samples of magnetic resonance responsive material, said RF coils connected in series, and wherein each of said RF coils encircles one of said plurality of samples of magnetic resonance responsive material
  • said RF coil comprises a pluralty of RF coils, the number of which corresponds to the number of said plurality of samples of magnetic resonance responsive material, said RF coils connected in series, and wherein each of said RF coils encircles one of said plurality of samples of magneto resonance responsive material, and is encircled by a ring of magnetic resonance responsive material
  • the gaps between said three samples are distinctly different whereby this aides in figuring the directionality of said device
  • the device is incorporated in a surgeryroom tool
  • said surgery-room tool comprises a suction tube
  • a MRI apparatus incorporating a pointing device, said device comprising a member of a predetermined shape, a front end and a back end, the front end comprising a magnetic structure for the provision of a magnetic field, gradient coils, RF transmit coil and RF receive coil, and the back end comprising a central processing unit, at least two gradient amplifiers, RF amplifier, MRI spectrometer, MRI controller and display unit at least one sample of magnetic resonance responsive material placed within said member in a predetermined position, said sample geometrically arranged to have a distinct directionality; whereby when said pointing device is irtroduced into said magnetic resonance imaging apparatus image region, the position of the sample may be obtained and superimposed on an image of said target.
  • a method for the determination of position and orientation of a pointing device relative to a desired target in magnetic resonance imaging comprising the steps of:
  • said method further comprises the steps of:
  • said magnetic resonance responsive material of said pointing device is geometrically arranged to have a distinct directionality.
  • Figure 1 illustrates an MRI pointing device in accordance with a preferred embodiment of the present invention, having a plurality of magnetic resonance responsive samples.
  • Figure 2 illustrates an MRI pointing device in accordance with another preferred embodiment of the present invention, having a magnetic resonance responsive sample having a shape of distinct determinable directionality.
  • Figure 3 depicts another embodiment of the pointing device of the present invention, having MR responsive samples in different sizes.
  • Figure 4 illustrates a pointing device in accordance with a preferred embodiment of the present invention incorporated in a suction tube.
  • FIG. 5 is a schematic diagram of a pointing device incorporated with an MRI apparatus, in accordance with a preferred embodiment of the present invention.
  • Figure 6 shows the procedure steps of applying the method of determiniig the position and orientation of a pointing device in accordance with a preferred embodiment of the present invention.
  • Figure 7 provides an illustration of an effectively on-line determination of the position and orientation of the pointing device and pacing it on a desired target in accordance to the present invention.
  • Figure 8 shows an alternative procedure steps of applying the method of determining the position and orientation of a pointing device in accordance with a preferred embodiment of the pesent invention.
  • a main aspect of the present invention is the provision of a pointing device with distinct detectable directionality suitable for use in cooperation with an MRI apparatus.
  • the pointing device is piovided with at least one magnetic resonance responsive sample that can be detected and imaged by the MRI apparatus.
  • the pointing device containing the MR responsive sample is positioned at the patient's imaged region - which may be an open cavity within the patient's body or inside a duct within the body, or over the skin or any other position over the body - and is subjected to a predetermined MRI image acquisition sequence
  • the MRI antenna picks up the induced signal from the MR responsive sample contained within the pointing device and the MRI apparatus displays the pointing device's position on the image of the patient's organ or body part
  • Figure 1 illustrates an MRI pointing device in accordance with a preferred embodiment of the present invention, ha ing a plurality of magnetic resonance responsive samples
  • the pointing device comprises a tube 1 , or a similar container, in which three samples 2, 3, 4, in the shape of discs, made from an MR responsive material, such as water or gadolinium or nickel chibride (NiCI) solution , are placed, in a distinct directionalitydeterminable arrangement, where the gaps between the MR responsive samples are distinctly different
  • MR responsive material such as water or gadolinium or nickel chibride (NiCI) solution
  • annular void 32 containing water, or other MR responsive material is provided This is done in order to enhance the signal obtained by the coil, as the coil is sensitive to internal as well as outside Signal responses By engulfing the coil with MR responsive sample, the coil picks up a stronger response
  • an RF coil is provided in the vicinity of the samples The RF coil serve as a local antenna for the reception of locally induced MR signal (i e the induced signal of the MR responsive sample)
  • i e RF coil 5 is located near MR responsive sample 2
  • RF coil 6 is located near MR responsive sample 3
  • RF coil 7 is located neat MR responsive sample 4 It is recommended to connect RF coils 5, 6 and 7 in series and provide them with two electrical wires (or terminals) 8 to be electrically connected to the MRI apparatus receiver
  • RF coils 5, 6 and 7 act as a single coil when connected in series
  • Another optional embodiment is to use three different MR responsive samples, i e made from different materials or same material but with different densities or concentrations , so as to allow distinction between the samples It is noted that it may be possible to provide a pointing device with more than three MR responsive samples and in different configuration as long as the arrangement of the MR responsive sample within the device has a distinct MR! detectable directionality Any such device would still be covered by the scope of the present invention and the accompanying Qaims Figure 2 illustrates an MRI pointing device in accordance with another preferred embodiment of the present invention, having a magnetic resonance responsive sample having a shape of distinct determinable directionality
  • the MR responsive sample 12 is located inside a tube 1 1 , having the shape of a cone, with a broad base at one end and a tipped point at the other end
  • the MR responsive sample 12 is encircled by an RF coil 13, which is provided with electrical wiring 15 for connection to an MRI apparatus receiver
  • the pointing device of the present invention may be incorporated in other tools, such as at the distal end of a suction tube used in surgery to evacuate blood or other fluids from the surgery site, etc
  • Figure 3 illustrates another preferred embodiment of the present invention, where the pointing device comprises three MR responsive samples having different sizes.
  • the pointing device 110 comprises a body in the form of a tube 114 having three voids, 116, 118 and 120 containing MR respons/e sample (like water).
  • the voids differ in their sizes, in a predetermined manner so as to allow determining the directionality of the pointing device by viewing the MR image in which it is shown. The viewer may determine the directionality by spotting Hie differences in sizes on the MR samples as they appear on the image.
  • the coils 122 are immersed in the MR responsive sample. Again this is done in order to enhance the appearance of the MR responsive samples on the image acquired.
  • the coils are connected in series and are provided with wiring 124 that may be connected to the electronic circuit of the MRI apparatus.
  • Figure 4 illustrates a pointing device in accordance with a preferred embodiment of the present invention incorp ⁇ ated in a suction tube.
  • the suction tube 21 is primarily a fluid evacuation device aimed at evacuating blood or other fluids from the surgery site within the patient.
  • the suction tube's proximal end is connected to a suction pump 29 which pumps the fluids away from the surgery site.
  • the tube's distal end is placed by a member of the surgical team adjacent the fluids to be evacuated and the fluid is then pumped away into the tube's conduit 21.
  • three MR responsive samples are provided arranged in rings 22, 23, 24, unevenly spaced so that the distance between the ring 22 nearest to the edge of the tube and the middle ring 23, is notably different from the distance between the middle ring 23 and the third ring 24.
  • the distance between the first two rings is smaller than the distance between the middle and the last ring, but an opposite arrangement would still be covered by the scope of the present invention.
  • the pointing device of the present invention allows the surgical team to determine with high accuracy the location and orientation of the pointer and thus facilitates marking specific targets during the surgery for operation.
  • the ability to determine the directionality of the pointing device brings about the ability to pinpoint a target, be it a tumor to be removed in a brain surgery, or a blood vessel etc., minimizing the risk for inadvertent or accidental damage being inflicted during surgery.
  • the pointing device of the present invention can be used to aid the surgical team in determining the precise direction they should choose to make an incision in order to get to the target to be operated.
  • FIG. 5 is a schematic diagram of a pointing device incorporated with an MRI apparatus, in accordance with a preferred embodiment of the present invention.
  • a magnetic resonance imaging apparatus 50 comprises a front end and a back end, the front end comprising a magnetic structure 51 for the provision of a magnetic field, at least two gradient coils, RF transmit coil 52 and RF receive coil 53, and the back end comprising a central processing unit 60(usually a host computer), gradient amplifiers 54, RF amplifier 55, MRI spectrometer 56, MRI controller 57 and display unit 58.
  • the RF coil, or coils, of the pointing device 59 of the present invention is electrically connected to the RF amplifier 55, which transmits an amplified response signal to the central processing unit 60 for processing of the signal to obtain an image which is displayed on the display unit.
  • a member of the medical staff 62 (usually a surgeon) holds the pointing device 59 and introduces it to the organ of the patient 61 that is imaged.
  • the CPU is programmed to compute the position of the pointing device and superpose it on the retrieved image of the patient's organ under examination in the manner explained hereafter.
  • the method of determining the position and orientation of the pointing device according to the present invention preferably involves two alternative procedures:
  • a first suggested procedure comprises the following steps: 1. placing a patient in imaging region of a MRI apparatus; 2. applying predetermined imaging sequence view gradient strength, oblique axes and bandwidth;
  • each view gadient twice in reversed polarities is in order to cancel effects of local distortions caused by flaws in the magnetic field, as in the case of image elements that are not found in the same position, their true position may determined by calculating the true position to be exactly in the middle between the position of the element when applying the first view gradient and the position of the same element when applying the same view gradient with reversed polarity.
  • the pointing device of the present invention is primarily intended to be used as a pointing tool, to help the surgical team locate their target and direct their incision tool or any other device to a desired location; b. It is stipulated that a surgical team would not be really interested in the real coordinates of the pointing device but rather in the relative position of the pointing device with respect to the patient's organ image. The surgical team would track the position of a pointing device on the monitor relative to the image of the organ under examination, and would try to make sense of that relative position in determining where to place a surgery tool, or where to perform an incision etc. c. Superimposing the pointing device position on the original image using the image coordinates as reference eliminates the possible error, and therefore would account for a precise superposition of the pointing device image on the previously retrieved image.
  • the imaging sequence used for the acquisition of the organ image can be either a 2-dimensional multi slice sequence or a 3-dimensional sequence.
  • the significantly shortened acquisition time of the pointing device position allows a fast sequential acquisition of a series of images of the pointing device (see Figure 7), during which the pointing device is relocated in the imaged region until the surgeon (or the surgical personnel operating the device) verifies that the pointing device is positioned where was desired.
  • the surgeon first marks the predetermined target on the image. He then places the pointing device in the presumed target location and a superimposed position of the pointing device on the organ image is acquired. If the pointing device is found not to be an the target the surgeon relocates the pointing device to another location and another superimposed image is acquired. If the pointing device is still off the target the surgeon determines whether the pointing device is closer to the target than it was before and consequently may determine in which direction the pointing device ought to be moved in order to coincide with the target.
  • the method then comprises the following additional steps: 1. determining whether the pointing device is on said target;
  • the introduction of the pointing device of the present invention provides the surgical team with a reliable way to determine the location of a target (such as a malignant tissue) on the acquired image, and allows the precise positioning of a surgical tool on the target.
  • the separate acquisition of the pointing device image and consequent provision of a superimposed image is a fast method, which in effect allows the surgical team to obtain an almost on-line image of the pointing device.
  • FIG. 8 shows alternative procedure steps of applying the method of determining the position and orientation of a pointing device in accordance with a preferred embodiment of the present invention
  • An alternative procedure of determining the position and orientation ofthe pointing device according to the present invention comprises a simultaneous imaging of the patient's organ with the pointing device (see Figure 5) It involves the following steps
  • the pointing device When derivation of the coordinates of the pointing device are desired, one must keep track on the Larmor (central) frequency
  • the pointing device may be placed in a predetermined location, preferably out of the field of view of the MRI apparatus Before acquiring an imagethe MRI apparatus can be made to automatically detect the Larmor frequency at that location and register it Later, when it is desired to use the pointing device, the pointing device is again placed in the same predetermined location in order to detect clanges in the Larmor frequency from the time an image was acquired updating the MRI apparatus with the same change in frequency.
  • the pointing device of the present invention makes it simpler and easier for the surgeon to determine the position of the targetand optimal position of the surgery tool to be used.
  • the pointing device is a physical item of finite dimensions, it may be positioned only as close to the target as the distance of the target from the upper surface of the imaged region, such a? in the case of a malignant tumor, which is found inside the head of a patient, before the opening of the skull in surgery. From knowing the actual dimensions of the pointing device, and in particular the distance of the MR active sample edge from the pointing device tip, it can be taken into consideration in a program calculating the position of the pointing device and adjustment can be made to mark the tip of the pointing device on the superposed image.
  • a virtual straight line, or any predetermined cure extending coaxially beyond the pointing device tip, which will allow the surgeon to determine the direction of the target relative to a certain reference point.
  • the pointing device may than be positioned on a predetermined reference point and the surgeon may twist and reorientate the pointing device until the virtual line provided on the superimposed image coincide with the target, thus helping the surgeon to determine the direction in which he must work his way towards the target.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

On décrit un dispositif de pointage destiné à être utilisé en association avec un appareil d'imagerie par résonance magnétique. Le dispositif de pointage comprend : un élément ayant une forme prédéterminée, au moins un échantillon de matière réagissant à la résonance magnétique qui est placé à l'intérieur dudit élément dans une position prédéterminée, ledit échantillon étant placé de manière géométrique pour présenter une directivité distincte. Lorsque ledit dispositif est introduit dans la région d'imagerie de l'appareil d'imagerie par résonance magnétique, la position de l'échantillon peut être obtenue et indiquée sur une image de ladite cible.
PCT/IL2001/000318 2000-04-07 2001-04-05 Dispositif de pointage irm et procede de determination de la position et de l'orientation WO2001076453A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU48725/01A AU4872501A (en) 2000-04-07 2001-04-05 Mri pointing device and method for determining position and orientation

Applications Claiming Priority (2)

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US54538400A 2000-04-07 2000-04-07
US09/545,384 2000-04-07

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8423119B2 (en) 2005-10-17 2013-04-16 Koninklijke Philips Electronics N.V. Marker tracking and accuracy verification for interventional magnetic resonance by measuring magnetic field inhomogeneity and determining a noise figure of merit

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5782764A (en) * 1995-11-07 1998-07-21 Iti Medical Technologies, Inc. Fiber composite invasive medical instruments and methods for use in interventional imaging procedures
DE19727081A1 (de) * 1997-06-25 1999-01-07 Siemens Ag Verfahren zur Ortsbestimmung eines positionierbaren Objekts in einem Untersuchungsobjekt mittels magnetischer Resonanz und Vorrichtung zur Durchführung des Verfahrens

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8423119B2 (en) 2005-10-17 2013-04-16 Koninklijke Philips Electronics N.V. Marker tracking and accuracy verification for interventional magnetic resonance by measuring magnetic field inhomogeneity and determining a noise figure of merit

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AU4872501A (en) 2001-10-23

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