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WO2001073114A3 - Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation - Google Patents

Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation Download PDF

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Publication number
WO2001073114A3
WO2001073114A3 PCT/US2001/007619 US0107619W WO0173114A3 WO 2001073114 A3 WO2001073114 A3 WO 2001073114A3 US 0107619 W US0107619 W US 0107619W WO 0173114 A3 WO0173114 A3 WO 0173114A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
analyte
sample
kits
methods
Prior art date
Application number
PCT/US2001/007619
Other languages
English (en)
Other versions
WO2001073114A2 (fr
Inventor
Tianmei Ouyang
Original Assignee
Lifescan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifescan Inc filed Critical Lifescan Inc
Priority to KR1020027012698A priority Critical patent/KR20020089412A/ko
Priority to EP01916527A priority patent/EP1268849A2/fr
Priority to MXPA02009469A priority patent/MXPA02009469A/es
Priority to AU2001243542A priority patent/AU2001243542A1/en
Priority to CA002404421A priority patent/CA2404421A1/fr
Priority to IL15126201A priority patent/IL151262A0/xx
Priority to PL01357180A priority patent/PL357180A1/xx
Priority to JP2001570828A priority patent/JP2003528623A/ja
Publication of WO2001073114A2 publication Critical patent/WO2001073114A2/fr
Publication of WO2001073114A3 publication Critical patent/WO2001073114A3/fr
Priority to HK03102161.6A priority patent/HK1050030A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90212—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

L'invention concerne des systèmes de production de signal, des compositions de réactifs, des bandes d'essai ainsi que des matériels composés de ceux-ci, de même que leur procédé d'utilisation dans la détection d'un analyte dans un échantillon. Les systèmes de production de signal de l'invention sont caractérisés en ce qu'ils présentent au moins un premier et un second agent de transfert d'électrons et un indicateur d'oxydoréduction, dans de nombreux modes de réalisation préférés. Les systèmes contiennent un agent de transfert d'électrons protéiniques et non protéiniques, par exemple un composé de phénazine et une diaphorase. Dans de nombreux modes de réalisation préférés, les systèmes et les matériels de l'invention comprennent également au moins un cofacteur enzymatique ou une enzyme et souvent l'un et l'autre présentant une activité d'oxydation d'analyte, par exemple, une déhydrogénase d'analyte. Les systèmes, les compostions de réactifs, les bandes d'essai ainsi que les matériels de l'invention trouvent une utilisation dans la détection d'une large variété d'analytes dans un échantillon, tel qu'un échantillon physiologique, par exemple le sang ou une fraction de celui-ci.
PCT/US2001/007619 2000-03-28 2001-03-08 Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation WO2001073114A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020027012698A KR20020089412A (ko) 2000-03-28 2001-03-08 환원된 보조인자를 검출하기 위한 시약 및 방법
EP01916527A EP1268849A2 (fr) 2000-03-28 2001-03-08 Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation
MXPA02009469A MXPA02009469A (es) 2000-03-28 2001-03-08 Reactivos y metodos para detectar un cofactor reducido.
AU2001243542A AU2001243542A1 (en) 2000-03-28 2001-03-08 Reagent systems for detecting the presence of a reduced cofactor in a sample and methods for using the same
CA002404421A CA2404421A1 (fr) 2000-03-28 2001-03-08 Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation
IL15126201A IL151262A0 (en) 2000-03-28 2001-03-08 Reagents and methods for detecting a reduced cofactor
PL01357180A PL357180A1 (en) 2000-03-28 2001-03-08 Reagent systems for detecting the presence of a reduced cofactor in a sample and methods for using the same
JP2001570828A JP2003528623A (ja) 2000-03-28 2001-03-08 サンプル中の還元された補助因子の存在を検出するための試薬システムおよびその使用方法
HK03102161.6A HK1050030A1 (zh) 2000-03-28 2003-03-25 檢測還原的輔因子的試劑和方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53720300A 2000-03-28 2000-03-28
US09/537,203 2000-03-28

Publications (2)

Publication Number Publication Date
WO2001073114A2 WO2001073114A2 (fr) 2001-10-04
WO2001073114A3 true WO2001073114A3 (fr) 2002-03-28

Family

ID=24141653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/007619 WO2001073114A2 (fr) 2000-03-28 2001-03-08 Systemes de reactifs pour detecter la presence d'un cofacteur reduit dans un echantillon et leurs procedes d'utilisation

Country Status (13)

Country Link
EP (1) EP1268849A2 (fr)
JP (1) JP2003528623A (fr)
KR (1) KR20020089412A (fr)
CN (1) CN1419604A (fr)
AR (1) AR027726A1 (fr)
AU (1) AU2001243542A1 (fr)
CA (1) CA2404421A1 (fr)
HK (1) HK1050030A1 (fr)
IL (1) IL151262A0 (fr)
MX (1) MXPA02009469A (fr)
PL (1) PL357180A1 (fr)
RU (1) RU2266543C2 (fr)
WO (1) WO2001073114A2 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US7604721B2 (en) 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050103624A1 (en) 1999-10-04 2005-05-19 Bhullar Raghbir S. Biosensor and method of making
GB0204232D0 (en) * 2002-02-22 2002-04-10 Isis Innovation Assay
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US8071030B2 (en) 2003-06-20 2011-12-06 Roche Diagnostics Operations, Inc. Test strip with flared sample receiving chamber
CA2529651C (fr) 2003-06-20 2017-02-21 F. Hoffmann-La Roche Ag Bande de test comportant une chambre de reception d'echantillon evasee
ITMI20050881A1 (it) * 2005-05-16 2006-11-17 Anna Favre Kit diagnostico per la malattia di hirschsprung megalon congenito
DE102006002165A1 (de) * 2006-01-17 2007-07-19 Merck Patent Gmbh Verfahren und Mittel zur enzymatischen Bestimmung von Acetat
EP2542887B1 (fr) * 2010-03-01 2013-06-19 System Biologie AG Bandelette réactive pour la détection d'équol
CN102520198A (zh) * 2011-11-21 2012-06-27 宁波美康生物科技股份有限公司 乙醇浓度检测试剂盒及其制备方法
CN102520150A (zh) * 2011-12-08 2012-06-27 上海高丰医疗电器有限公司 一种伽马-羟基丁酸的测定诊断试纸及其制备方法
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
US8921061B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
CN108359710B (zh) * 2018-02-11 2019-04-30 山东大学齐鲁医院 葡萄糖磷酸异构酶的酶显色定量测定试剂盒及测定方法
CN110117791B (zh) * 2019-05-23 2023-11-10 电子科技大学 一种用于高密度互联印制电路板棕化液的结合力促进剂

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629697A (en) * 1982-12-24 1986-12-16 Merck Patent Gesellschaft Mit Beschrankter Haftung Test system and procedure for the determination of NAD (P) H
EP0279988A1 (fr) * 1986-12-16 1988-08-31 Enzymatics, Inc. Système numérique de contrôle colorimétrique
US4824779A (en) * 1984-02-29 1989-04-25 Kyowa Medex Co., Ltd. Method for the determination of the reduced form of nicotinamide adenine dinucleotide
US5278047A (en) * 1989-04-25 1994-01-11 Lilja Jan E Method of analysis, reagent composition and use thereof for glucose determination
US5902731A (en) * 1998-09-28 1999-05-11 Lifescan, Inc. Diagnostics based on tetrazolium compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4311464A1 (de) * 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4629697A (en) * 1982-12-24 1986-12-16 Merck Patent Gesellschaft Mit Beschrankter Haftung Test system and procedure for the determination of NAD (P) H
US4824779A (en) * 1984-02-29 1989-04-25 Kyowa Medex Co., Ltd. Method for the determination of the reduced form of nicotinamide adenine dinucleotide
EP0279988A1 (fr) * 1986-12-16 1988-08-31 Enzymatics, Inc. Système numérique de contrôle colorimétrique
US5278047A (en) * 1989-04-25 1994-01-11 Lilja Jan E Method of analysis, reagent composition and use thereof for glucose determination
US5902731A (en) * 1998-09-28 1999-05-11 Lifescan, Inc. Diagnostics based on tetrazolium compounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RAAP A K ET AL: "THE PHENAZINE METHOSULFATE TETRAZOLIUM CAPTURE REACTION IN NADP DEPENDENT DEHYDROGENASE CYTOCHEMISTRY 2. A NOVEL HYPOTHESIS FOR THE MODE OF ACTION OF PHENAZINE METHOSULFATE AND A STUDY OF THE PROPERTIES OF REDUCED PHENAZINE METHOSULFATE", HISTOCHEMICAL JOURNAL, vol. 15, no. 9, 1983, pages 881 - 894, XP001050450, ISSN: 0018-2214 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US7604721B2 (en) 2003-06-20 2009-10-20 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US9410915B2 (en) 2004-06-18 2016-08-09 Roche Operations Ltd. System and method for quality assurance of a biosensor test strip

Also Published As

Publication number Publication date
WO2001073114A2 (fr) 2001-10-04
CA2404421A1 (fr) 2001-10-04
CN1419604A (zh) 2003-05-21
RU2266543C2 (ru) 2005-12-20
AR027726A1 (es) 2003-04-09
AU2001243542A1 (en) 2001-10-08
JP2003528623A (ja) 2003-09-30
KR20020089412A (ko) 2002-11-29
HK1050030A1 (zh) 2003-06-06
PL357180A1 (en) 2004-07-26
RU2002123839A (ru) 2004-03-10
MXPA02009469A (es) 2003-02-24
IL151262A0 (en) 2003-04-10
EP1268849A2 (fr) 2003-01-02

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