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WO2001072840A3 - Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof - Google Patents

Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof Download PDF

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Publication number
WO2001072840A3
WO2001072840A3 PCT/US2001/009657 US0109657W WO0172840A3 WO 2001072840 A3 WO2001072840 A3 WO 2001072840A3 US 0109657 W US0109657 W US 0109657W WO 0172840 A3 WO0172840 A3 WO 0172840A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
molecules encoding
protein coupled
coupled receptors
Prior art date
Application number
PCT/US2001/009657
Other languages
French (fr)
Other versions
WO2001072840A2 (en
Inventor
Aihui Wang
Anibal Cravchik
Francesco Valentina Di
Ellen M Beasley
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Priority to EP01926435A priority Critical patent/EP1278840A2/en
Priority to CA002404563A priority patent/CA2404563A1/en
Priority to AU2001252968A priority patent/AU2001252968A1/en
Priority to JP2001571771A priority patent/JP2003530834A/en
Publication of WO2001072840A2 publication Critical patent/WO2001072840A2/en
Publication of WO2001072840A3 publication Critical patent/WO2001072840A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the Human genome, the GPCR peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the GPCR peptides and methods of identifying modulators of the GPCR peptides.
PCT/US2001/009657 2000-03-27 2001-03-27 Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof WO2001072840A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01926435A EP1278840A2 (en) 2000-03-27 2001-03-27 Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof
CA002404563A CA2404563A1 (en) 2000-03-27 2001-03-27 Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof
AU2001252968A AU2001252968A1 (en) 2000-03-27 2001-03-27 Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof
JP2001571771A JP2003530834A (en) 2000-03-27 2001-03-27 Human G protein-coupled receptors belonging to the isolated proto-oncogene subfamily, nucleic acid molecules encoding human GPCR proteins, and uses thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US19231000P 2000-03-27 2000-03-27
US60/192,310 2000-03-27
US62981700A 2000-07-31 2000-07-31
US09/629,817 2000-07-31

Publications (2)

Publication Number Publication Date
WO2001072840A2 WO2001072840A2 (en) 2001-10-04
WO2001072840A3 true WO2001072840A3 (en) 2002-03-21

Family

ID=26887962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009657 WO2001072840A2 (en) 2000-03-27 2001-03-27 Isolated human g-protein coupled receptors of the mas proto-oncogene subfamily, nucleic acid molecules encoding human gpcr proteins, and uses thereof

Country Status (5)

Country Link
EP (1) EP1278840A2 (en)
JP (1) JP2003530834A (en)
AU (1) AU2001252968A1 (en)
CA (1) CA2404563A1 (en)
WO (1) WO2001072840A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020062013A1 (en) * 1999-12-28 2002-05-23 Peter Lind Novel G protein-coupled receptors
WO2006066599A2 (en) * 2004-12-22 2006-06-29 Rheoscience A/S Mas related g protein coupled receptors as drug targets

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003181A2 (en) * 1988-09-24 1990-04-05 Medical Research Council Peptide antagonists for use in cancer therapy, and the use of mas oncogene and its product
WO1996016087A1 (en) * 1994-11-18 1996-05-30 Human Genome Sciences, Inc. G-protein coupled receptor
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2001048015A2 (en) * 1999-12-28 2001-07-05 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4855393A (en) * 1992-09-10 1994-03-29 New York University Polypeptides of g-coupled receptor proteins, and compositions and methods thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990003181A2 (en) * 1988-09-24 1990-04-05 Medical Research Council Peptide antagonists for use in cancer therapy, and the use of mas oncogene and its product
WO1996016087A1 (en) * 1994-11-18 1996-05-30 Human Genome Sciences, Inc. G-protein coupled receptor
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
WO2001048015A2 (en) * 1999-12-28 2001-07-05 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MARTIN ET AL.: "Expression of the mas proto-oncogene in the rat hippocampal formation is regulated by neuronal activity", MOLECULAR BRAIN RESEARCH, vol. 19, 1993, pages 303 - 309, XP001050386 *
See also references of EP1278840A2 *

Also Published As

Publication number Publication date
AU2001252968A1 (en) 2001-10-08
WO2001072840A2 (en) 2001-10-04
JP2003530834A (en) 2003-10-21
CA2404563A1 (en) 2001-10-04
EP1278840A2 (en) 2003-01-29

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