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WO2001068840A3 - REGULATION OF HUMAN DIAZEPAM BINDING INHIBITOR/ACYL-CoA-LIKE PROTEIN - Google Patents

REGULATION OF HUMAN DIAZEPAM BINDING INHIBITOR/ACYL-CoA-LIKE PROTEIN Download PDF

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Publication number
WO2001068840A3
WO2001068840A3 PCT/EP2001/002780 EP0102780W WO0168840A3 WO 2001068840 A3 WO2001068840 A3 WO 2001068840A3 EP 0102780 W EP0102780 W EP 0102780W WO 0168840 A3 WO0168840 A3 WO 0168840A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
protein
coa
acyl
binding inhibitor
Prior art date
Application number
PCT/EP2001/002780
Other languages
French (fr)
Other versions
WO2001068840A2 (en
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to AU2001250379A priority Critical patent/AU2001250379A1/en
Publication of WO2001068840A2 publication Critical patent/WO2001068840A2/en
Publication of WO2001068840A3 publication Critical patent/WO2001068840A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Reagents which regulate human DBI/ACBP-like protein binding activity and reagents which bind to human DBI/ACBP-like protein gene products can be used to regulate cell proliferation. Such regulation is particularly useful for treating malignant cells, neurological diseases, and regulating steroid biosynthesis.
PCT/EP2001/002780 2000-03-14 2001-03-13 REGULATION OF HUMAN DIAZEPAM BINDING INHIBITOR/ACYL-CoA-LIKE PROTEIN WO2001068840A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001250379A AU2001250379A1 (en) 2000-03-14 2001-04-13 Regulation of human diazepam binding inhibitor/acyl-coa-like protein

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18903800P 2000-03-14 2000-03-14
US60/189,038 2000-03-14
US25139300P 2000-12-06 2000-12-06
US60/251,393 2000-12-06

Publications (2)

Publication Number Publication Date
WO2001068840A2 WO2001068840A2 (en) 2001-09-20
WO2001068840A3 true WO2001068840A3 (en) 2002-03-07

Family

ID=26884722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002780 WO2001068840A2 (en) 2000-03-14 2001-03-13 REGULATION OF HUMAN DIAZEPAM BINDING INHIBITOR/ACYL-CoA-LIKE PROTEIN

Country Status (2)

Country Link
AU (1) AU2001250379A1 (en)
WO (1) WO2001068840A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3906037A4 (en) * 2019-01-29 2023-03-01 Holobiome, Inc. Methods and compositions for treating and preventing cns disorders and other conditions caused by gut microbial dysbiosis
CN118141894A (en) * 2024-02-04 2024-06-07 河北医科大学 Application of DBI and hydrolysate peptide thereof in preparation of medicine for relieving peripheral nerve pain

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006847A1 (en) * 1996-08-16 1998-02-19 Incyte Pharmaceuticals, Inc. Human dbi/acbp-like protein
WO2001025436A2 (en) * 1999-10-05 2001-04-12 Curagen Corporation Endozepine-like polypeptides and polynucleotides encoding same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998006847A1 (en) * 1996-08-16 1998-02-19 Incyte Pharmaceuticals, Inc. Human dbi/acbp-like protein
WO2001025436A2 (en) * 1999-10-05 2001-04-12 Curagen Corporation Endozepine-like polypeptides and polynucleotides encoding same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM EMBL Heidelberg, Germany; 6 November 1999 (1999-11-06), ROWEN L ET AL.: "Sequencing of human chromosome 15 D15S146-D15S117 region", XP002182180 *
LIHRMANN I ET AL: "Frog diazepam-binding inhibitor: Peptide sequence, cDNA cloning, and expression in the brain.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 91, no. 15, 1994, 1994, pages 6899 - 6903, XP002182179, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2001068840A2 (en) 2001-09-20
AU2001250379A1 (en) 2001-09-24

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