WO2001066689A3 - Nouveaux acides nucleiques et polypeptides - Google Patents
Nouveaux acides nucleiques et polypeptides Download PDFInfo
- Publication number
- WO2001066689A3 WO2001066689A3 PCT/US2001/004942 US0104942W WO0166689A3 WO 2001066689 A3 WO2001066689 A3 WO 2001066689A3 US 0104942 W US0104942 W US 0104942W WO 0166689 A3 WO0166689 A3 WO 0166689A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acids
- polypeptides
- novel nucleic
- novel
- present
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/221,278 US20040034208A1 (en) | 2001-03-05 | 2001-03-05 | Novel nucleic acids and polypeptides |
AU2001245280A AU2001245280A1 (en) | 2000-03-07 | 2001-03-05 | Novel nucleic acids and polypeptides |
CA002402293A CA2402293A1 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
EP01918174A EP1261743A2 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
US10/291,172 US20030228584A1 (en) | 2000-03-07 | 2002-11-08 | Novel nucleic acids and polypeptides |
Applications Claiming Priority (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51970500A | 2000-03-07 | 2000-03-07 | |
US09/519,705 | 2000-03-07 | ||
US57445400A | 2000-05-19 | 2000-05-19 | |
US09/574,454 | 2000-05-19 | ||
US59619300A | 2000-06-17 | 2000-06-17 | |
US09/596,193 | 2000-06-17 | ||
US61684700A | 2000-07-14 | 2000-07-14 | |
US09/616,847 | 2000-07-14 | ||
US66536300A | 2000-09-19 | 2000-09-19 | |
US09/665,363 | 2000-09-19 | ||
US69326700A | 2000-10-20 | 2000-10-20 | |
US09/693,267 | 2000-10-20 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/291,172 Continuation-In-Part US20030228584A1 (en) | 2000-03-07 | 2002-11-08 | Novel nucleic acids and polypeptides |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001066689A2 WO2001066689A2 (fr) | 2001-09-13 |
WO2001066689A3 true WO2001066689A3 (fr) | 2002-05-30 |
Family
ID=27560092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/004942 WO2001066689A2 (fr) | 2000-03-07 | 2001-03-05 | Nouveaux acides nucleiques et polypeptides |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1261743A2 (fr) |
AU (1) | AU2001245280A1 (fr) |
CA (1) | CA2402293A1 (fr) |
WO (1) | WO2001066689A2 (fr) |
Cited By (5)
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US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
US7033790B2 (en) | 2001-04-03 | 2006-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
WO2024138128A2 (fr) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Conjugués d'agent de dégradation de céréblon et leurs utilisations |
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US6953682B2 (en) | 2000-02-10 | 2005-10-11 | Millennium Pharmaceuticals, Inc. | Nucleic acid sequences encoding adenylate kinase, phospholipid scramblase-like, DNA fragmentation factor-like, phosphatidylserine synthase-like, and atpase-like molecules and uses therefor |
EP1343899A2 (fr) * | 2000-12-14 | 2003-09-17 | Bayer Aktiengesellschaft | Regulation de l'uridine kinase humaine |
US20040072997A1 (en) * | 2000-12-20 | 2004-04-15 | Alsobrook John P. | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
WO2002074906A2 (fr) * | 2001-03-16 | 2002-09-26 | Eli Lilly And Company | Proteines de mammiferes lp et reactifs associes |
JP2005536439A (ja) | 2001-09-18 | 2005-12-02 | ジェネンテック・インコーポレーテッド | 腫瘍の診断及び治療のための組成物と方法 |
AU2003226444A1 (en) * | 2002-04-01 | 2003-10-13 | Asahi Kasei Pharma Corporation | Vascularization controlling gene |
CA2486060A1 (fr) * | 2002-05-15 | 2003-11-27 | Avalon Pharmaceuticals | Gene lie au cancer servant de cible pour la chimiotherapie |
DK1513934T3 (da) | 2002-06-06 | 2011-05-02 | Oncotherapy Science Inc | Gener og polypeptider relateret til humane coloncancersygdomme |
GB0215295D0 (en) * | 2002-07-02 | 2002-08-14 | Inpharmatica Ltd | Proteins |
JP2007523608A (ja) * | 2003-03-26 | 2007-08-23 | ノバルティス アクチエンゲゼルシャフト | サイクリックamp応答エレメントアクティベータータンパク質およびそれに関連する使用 |
US7361747B2 (en) * | 2003-05-22 | 2008-04-22 | The University Of Hong Kong | Isolation and characterization of the precursor virus of human SARS virus: SARS-associated corona virus-like virus |
GB0320878D0 (en) * | 2003-09-05 | 2003-10-08 | Celltech R&D Ltd | A protein involved in carcinoma |
CA2543789A1 (fr) | 2003-10-23 | 2005-05-06 | Illumigen Biosciences, Inc. | Detection de mutations dans un gene associees a la resistance a l'infection virale, oas1 |
AU2004316290C1 (en) | 2003-11-06 | 2012-02-02 | Seagen Inc. | Monomethylvaline compounds capable of conjugation to ligands |
JP5234734B2 (ja) | 2004-06-01 | 2013-07-10 | ジェネンテック, インコーポレイテッド | 抗体−薬物結合体および方法 |
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CN107335062B (zh) | 2010-06-08 | 2021-09-24 | 基因泰克公司 | 半胱氨酸改造的抗体和偶联物 |
US20120121595A1 (en) * | 2010-10-11 | 2012-05-17 | University Of Southern California | FRAGMENT OF SECRETED HEAT SHOCK PROTEIN-90ALPHA (Hsp90ALPHA) AS VACCINES OR EPITOPE FOR MONOCLONAL ANTIBODY DRUGS OR TARGET FOR SMALL MOLECULE DRUGS AGAINST A RANGE OF SOLID HUMAN TUMORS |
JP5889912B2 (ja) | 2010-11-17 | 2016-03-22 | ジェネンテック, インコーポレイテッド | アラニニルメイタンシノール抗体コンジュゲート |
EP2707723B1 (fr) | 2011-05-12 | 2016-02-10 | Genentech, Inc. | Procédé lc-ms/ms de surveillance de réactions multiples pour détecter des anticorps thérapeutiques dans des échantillons animaux à l'aide de peptides de signature d'infrastructure |
BR112014009050B1 (pt) | 2011-10-14 | 2022-06-21 | Medimmune Limited | Conjugado anticorpo-fármaco de pirrolbenzodiazepinas, composição farmacêutica que compreende o mesmo, bem como compostos de pirrolbenzodiazepinas |
AU2013224591A1 (en) | 2012-02-22 | 2014-07-24 | Alethia Biotherapeutics Inc. | Co-use of a clusterin inhibitor with an EGFR inhibitor to treat cancer |
WO2013130093A1 (fr) | 2012-03-02 | 2013-09-06 | Genentech, Inc. | Biomarqueurs pour un traitement à base de composés chimiothérapeutiques anti-tubuline |
WO2014057120A1 (fr) | 2012-10-12 | 2014-04-17 | Adc Therapeutics Sàrl | Conjugués anticorps - pyrrolobenzodiazépine |
EP2766048B1 (fr) | 2012-10-12 | 2014-12-10 | Spirogen Sàrl | Pyrrolobenzodiazépines et leurs conjugués |
CN105102068B (zh) | 2012-10-12 | 2018-06-01 | Adc疗法责任有限公司 | 吡咯并苯并二氮杂卓-抗体结合物 |
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JP6392763B2 (ja) | 2012-10-12 | 2018-09-19 | エイディーシー・セラピューティクス・エス・アーAdc Therapeutics Sa | ピロロベンゾジアゼピン−抗体結合体 |
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EP3458101B1 (fr) | 2016-05-20 | 2020-12-30 | H. Hoffnabb-La Roche Ag | Conjugués anticorps-protac et procédés d'utilisation |
JP7022080B2 (ja) | 2016-05-27 | 2022-02-17 | ジェネンテック, インコーポレイテッド | 部位特異的抗体-薬物複合体の特徴付けのための生化学分析的方法 |
WO2017214024A1 (fr) | 2016-06-06 | 2017-12-14 | Genentech, Inc. | Médicaments conjugués d'anticorps silvestrol et procédés d'utilisation |
JP7093767B2 (ja) | 2016-08-11 | 2022-06-30 | ジェネンテック, インコーポレイテッド | ピロロベンゾジアゼピンプロドラッグ及びその抗体コンジュゲート |
EP3522933B1 (fr) | 2016-10-05 | 2021-12-15 | F. Hoffmann-La Roche AG | Procédés de préparation de conjugués anticorps-médicament |
GB201617466D0 (en) | 2016-10-14 | 2016-11-30 | Medimmune Ltd | Pyrrolobenzodiazepine conjugates |
GB201702031D0 (en) | 2017-02-08 | 2017-03-22 | Medlmmune Ltd | Pyrrolobenzodiazepine-antibody conjugates |
HUE054689T2 (hu) | 2017-02-08 | 2021-09-28 | Adc Therapeutics Sa | Pirrolobenzodiazepin-antitest konjugátumok |
US11260101B2 (en) * | 2017-02-28 | 2022-03-01 | Jinan University | Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof |
WO2018192944A1 (fr) | 2017-04-18 | 2018-10-25 | Medimmune Limited | Conjugués de pyrrolobenzodiazépine |
KR20190141666A (ko) | 2017-04-20 | 2019-12-24 | 에이디씨 테라퓨틱스 에스에이 | 항-axl 항체-약물 접합체로의 병용 요법 |
WO2018229222A1 (fr) | 2017-06-14 | 2018-12-20 | Adc Therapeutics Sa | Régimes posologiques pour l'administration d'un cam anti-cd19 |
FR3069156B1 (fr) * | 2017-07-21 | 2019-08-09 | Universite de Bordeaux | Clusterine pour son utilisation dans le traitement des micro-angiopathies thrombotiques |
SI3668874T1 (sl) | 2017-08-18 | 2022-04-29 | Medimmune Limited | Pirolobenzodiazepinski konjugati |
KR20220156974A (ko) | 2017-09-20 | 2022-11-28 | 주식회사 피에이치파마 | 타일란스타틴 유사체 |
GB201803342D0 (en) | 2018-03-01 | 2018-04-18 | Medimmune Ltd | Methods |
GB201806022D0 (en) | 2018-04-12 | 2018-05-30 | Medimmune Ltd | Pyrrolobenzodiazepines and conjugates thereof |
GB201814281D0 (en) | 2018-09-03 | 2018-10-17 | Femtogenix Ltd | Cytotoxic agents |
CN113056287A (zh) | 2018-10-24 | 2021-06-29 | 豪夫迈·罗氏有限公司 | 缀合的化学降解诱导剂及使用方法 |
WO2020123275A1 (fr) | 2018-12-10 | 2020-06-18 | Genentech, Inc. | Peptides de photoréticulation pour conjugaison spécifique de site à des protéines contenant fc |
GB201901197D0 (en) | 2019-01-29 | 2019-03-20 | Femtogenix Ltd | G-A Crosslinking cytotoxic agents |
MX2021010477A (es) | 2019-03-15 | 2021-10-01 | Medimmune Ltd | Dimeros de azetidobenzodiazepina y conjugados que los comprenden para uso en el tratamiento de cancer. |
GB2597532A (en) | 2020-07-28 | 2022-02-02 | Femtogenix Ltd | Cytotoxic compounds |
EP4426727A2 (fr) | 2021-11-03 | 2024-09-11 | Hangzhou Dac Biotech Co., Ltd. | Conjugaison spécifique d'un anticorps |
WO2024220546A2 (fr) | 2023-04-17 | 2024-10-24 | Peak Bio, Inc. | Anticorps et conjugués anticorps-médicament et procédés d'utilisation, processus synthétiques et intermédiaires |
-
2001
- 2001-03-05 EP EP01918174A patent/EP1261743A2/fr not_active Withdrawn
- 2001-03-05 AU AU2001245280A patent/AU2001245280A1/en not_active Abandoned
- 2001-03-05 WO PCT/US2001/004942 patent/WO2001066689A2/fr not_active Application Discontinuation
- 2001-03-05 CA CA002402293A patent/CA2402293A1/fr not_active Abandoned
Non-Patent Citations (2)
Title |
---|
DATABASE GENBANK [online] 6 February 1997 (1997-02-06), WANG ET AL.: "Direct submission", XP002908399, Database accession no. U51114 * |
WATSON ET AL.: "The science used in recombinant DNA industry. Recombinant DNA; A short course", 1983, W.H. FREEMAN AND COMPANY, NEW YORK, XP002945246 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7033790B2 (en) | 2001-04-03 | 2006-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
US7034132B2 (en) | 2001-06-04 | 2006-04-25 | Anderson David W | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
US9562049B2 (en) | 2012-12-21 | 2017-02-07 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
US9567340B2 (en) | 2012-12-21 | 2017-02-14 | Medimmune Limited | Unsymmetrical pyrrolobenzodiazepines-dimers for use in the treatment of proliferative and autoimmune diseases |
WO2024138128A2 (fr) | 2022-12-23 | 2024-06-27 | Genentech, Inc. | Conjugués d'agent de dégradation de céréblon et leurs utilisations |
Also Published As
Publication number | Publication date |
---|---|
WO2001066689A2 (fr) | 2001-09-13 |
EP1261743A2 (fr) | 2002-12-04 |
AU2001245280A1 (en) | 2001-09-17 |
CA2402293A1 (fr) | 2001-09-13 |
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