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WO2001046465A3 - Dispositif de microanalyse - Google Patents

Dispositif de microanalyse Download PDF

Info

Publication number
WO2001046465A3
WO2001046465A3 PCT/EP2000/013145 EP0013145W WO0146465A3 WO 2001046465 A3 WO2001046465 A3 WO 2001046465A3 EP 0013145 W EP0013145 W EP 0013145W WO 0146465 A3 WO0146465 A3 WO 0146465A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis device
microfluid analysis
microfluid
shaped
microstructure
Prior art date
Application number
PCT/EP2000/013145
Other languages
English (en)
Other versions
WO2001046465A2 (fr
Inventor
Per Andersson
Arvi Aksberg
Gunnar Ekstrand
Original Assignee
Gyros Ab
Per Andersson
Arvi Aksberg
Gunnar Ekstrand
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/fr
Application filed by Gyros Ab, Per Andersson, Arvi Aksberg, Gunnar Ekstrand filed Critical Gyros Ab
Priority to DE60035611T priority Critical patent/DE60035611T2/de
Priority to EP00992452A priority patent/EP1239962B1/fr
Priority to JP2001546961A priority patent/JP4612262B2/ja
Priority to US10/169,056 priority patent/US7261859B2/en
Priority to CA002395159A priority patent/CA2395159A1/fr
Priority to AU44105/01A priority patent/AU4410501A/en
Publication of WO2001046465A2 publication Critical patent/WO2001046465A2/fr
Publication of WO2001046465A3 publication Critical patent/WO2001046465A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0605—Metering of fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Centrifugal Separators (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

L'invention concerne une microstructure, laquelle est destinée à des fluides, est montée dans un disque rotatif (D) et possède une structure (7) définissant un volume en forme de U et reliée à sa base à un segment d'entrée d'une chambre également en forme de U (10).
PCT/EP2000/013145 1998-12-30 2000-12-22 Dispositif de microanalyse WO2001046465A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE60035611T DE60035611T2 (de) 1999-12-23 2000-12-22 Mikrofluid-analysevorrichtung
EP00992452A EP1239962B1 (fr) 1999-12-23 2000-12-22 Dispositif de microanalyse
JP2001546961A JP4612262B2 (ja) 1999-12-23 2000-12-22 ミクロ分析装置
US10/169,056 US7261859B2 (en) 1998-12-30 2000-12-22 Microanalysis device
CA002395159A CA2395159A1 (fr) 1999-12-23 2000-12-22 Dispositif de microanalyse
AU44105/01A AU4410501A (en) 1999-12-23 2000-12-22 Microanalysis device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP1999/010347 WO2000040750A1 (fr) 1998-12-30 1999-12-23 Procede de sequençage d'adn a l'aide d'un dispositif microfluidique
EPPCT/EP99/10347 1999-12-23
SE0001779A SE0001779D0 (sv) 2000-05-12 2000-05-12 Microanalysis device
SE0001779-8 2000-05-12

Publications (2)

Publication Number Publication Date
WO2001046465A2 WO2001046465A2 (fr) 2001-06-28
WO2001046465A3 true WO2001046465A3 (fr) 2001-12-27

Family

ID=20279665

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/013145 WO2001046465A2 (fr) 1998-12-30 2000-12-22 Dispositif de microanalyse

Country Status (7)

Country Link
JP (1) JP4612262B2 (fr)
AT (1) ATE367204T1 (fr)
AU (1) AU4410501A (fr)
CA (1) CA2395159A1 (fr)
DE (1) DE60035611T2 (fr)
SE (1) SE0001779D0 (fr)
WO (1) WO2001046465A2 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
SE0004296D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
SE0004297D0 (sv) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
WO2002046721A2 (fr) 2000-12-08 2002-06-13 Burstein Technologies, Inc. Disques optiques permettant de mesurer des analytes
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
WO2002075312A1 (fr) 2001-03-19 2002-09-26 Gyros Ab Caracterisation de variables de reaction
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
EP2281633A1 (fr) 2001-08-28 2011-02-09 Gyros Patent Ab Microcavite microfluidique de retention microfluidique et autres structures microfluidiques
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
WO2003024598A1 (fr) * 2001-09-17 2003-03-27 Gyros Ab Unite fonctionnelle de gestion des flux d'un dispositif de microfluidique
US7189368B2 (en) 2001-09-17 2007-03-13 Gyros Patent Ab Functional unit enabling controlled flow in a microfluidic device
JP3952019B2 (ja) * 2001-12-28 2007-08-01 株式会社日立ハイテクノロジーズ 抽出装置および化学分析装置並びに化学分析方法
JP4338529B2 (ja) 2002-04-08 2009-10-07 ユロス・パテント・アクチボラゲット ホーミングプロセス
JP4895504B2 (ja) * 2002-04-30 2012-03-14 ユィロス・パテント・アクチボラグ 集中マイクロ流体デバイス（ｅａ）
US8128889B2 (en) * 2002-04-30 2012-03-06 Arkray, Inc. Analyzing article, analyzer and method of analyzing a sample using the analyzing article, and a method of forming an opening in the analyzing article
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
CA2502053A1 (fr) 2002-10-13 2004-04-29 Picosep A/S Systeme microfluidique de separation de biomolecules
SE0301945D0 (sv) 2003-06-30 2003-06-30 Gyros Ab Confidence determination
JPWO2005012916A1 (ja) * 2003-08-05 2006-09-21 太陽誘電株式会社 試料分析装置及びディスク状試料分析媒体
US20090050620A1 (en) * 2004-01-06 2009-02-26 Gyros Ab Contact heating arrangement
EP1874469A4 (fr) 2005-04-14 2014-02-26 Gyros Patent Ab Dispositif microfluidique comprenant des valves digitiformes
GB2464721C (en) 2008-10-23 2013-08-14 Biosurfit Sa Jet deflection device
GB2466644B (en) 2008-12-30 2011-05-11 Biosurfit Sa Liquid handling
JP5521454B2 (ja) * 2009-09-15 2014-06-11 凸版印刷株式会社 試料分析チップ、これを用いた試料分析装置及び試料分析方法
GB2476474B (en) 2009-12-22 2012-03-28 Biosurfit Sa Surface plasmon resonance detection system
GB2479139A (en) 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
EP2486978A1 (fr) 2010-10-28 2012-08-15 Roche Diagnostics GmbH Support de test microfluidique destiné à répartir une quantité de liquide en quantités partielles
EP2455162A1 (fr) 2010-10-29 2012-05-23 Roche Diagnostics GmbH Elément micro-fluidique destiné à l'analyse d'un échantillon de liquide
US9933348B2 (en) 2011-12-08 2018-04-03 Biosurfit, S.A. Sequential aliqoting and determination of an indicator of sedimentation rate
JP5549719B2 (ja) * 2012-09-20 2014-07-16 ブラザー工業株式会社 検査対象受体
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
WO2017154750A1 (fr) * 2016-03-11 2017-09-14 パナソニック株式会社 Disque d'inspection d'échantillon de liquide et cartouche filtrante utilisée dans ce dernier, corps de disque, plaque de mesure, plaque de détection d'échantillon, système de détection de fluorescence, et procédé de détection de fluorescence

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
WO2000040750A1 (fr) * 1998-12-30 2000-07-13 Gyros Ab Procede de sequençage d'adn a l'aide d'un dispositif microfluidique

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4632908A (en) * 1984-05-03 1986-12-30 Abbott Laboratories Heating system for rotating members
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
WO1993019827A1 (fr) * 1992-04-02 1993-10-14 Abaxis, Inc. Rotor d'analyse comportant une chambre de melange de colorants
US6299839B1 (en) * 1995-08-31 2001-10-09 First Medical, Inc. System and methods for performing rotor assays
CA2286601A1 (fr) * 1997-05-16 1998-11-26 Alberta Research Council Systeme microfluidique et ses utilisations
JP3469585B2 (ja) * 1997-05-23 2003-11-25 ガメラ バイオサイエンス コーポレイション ミクロ流体工学システムでの流動運動を駆動するために向心的加速を使用するための装置および方法
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US5916522A (en) * 1997-08-07 1999-06-29 Careside, Inc. Electrochemical analytical cartridge

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
WO2000040750A1 (fr) * 1998-12-30 2000-07-13 Gyros Ab Procede de sequençage d'adn a l'aide d'un dispositif microfluidique

Also Published As

Publication number Publication date
DE60035611T2 (de) 2008-05-21
JP2003518250A (ja) 2003-06-03
AU4410501A (en) 2001-07-03
WO2001046465A2 (fr) 2001-06-28
JP4612262B2 (ja) 2011-01-12
SE0001779D0 (sv) 2000-05-12
DE60035611D1 (de) 2007-08-30
ATE367204T1 (de) 2007-08-15
CA2395159A1 (fr) 2001-06-28

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