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WO2000033667A3 - Bioflavonoids, anthocyanins and phenol compounds from cherries as antioxidants - Google Patents

Bioflavonoids, anthocyanins and phenol compounds from cherries as antioxidants Download PDF

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Publication number
WO2000033667A3
WO2000033667A3 PCT/US1999/029440 US9929440W WO0033667A3 WO 2000033667 A3 WO2000033667 A3 WO 2000033667A3 US 9929440 W US9929440 W US 9929440W WO 0033667 A3 WO0033667 A3 WO 0033667A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioflavonoids
anthocyanins
cherries
antioxidants
phenol compounds
Prior art date
Application number
PCT/US1999/029440
Other languages
French (fr)
Other versions
WO2000033667A2 (en
Inventor
Muraleedharan G Nair
Haibo Wang
Gale M Strasburg
Alden M Booren
James I Gray
Original Assignee
Univ Michigan State
Muraleedharan G Nair
Haibo Wang
Gale M Strasburg
Alden M Booren
James I Gray
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/317,310 external-priority patent/US6423365B1/en
Priority claimed from US09/329,604 external-priority patent/US6150408A/en
Application filed by Univ Michigan State, Muraleedharan G Nair, Haibo Wang, Gale M Strasburg, Alden M Booren, James I Gray filed Critical Univ Michigan State
Priority to KR10-2001-7007239A priority Critical patent/KR100441927B1/en
Priority to JP2000586180A priority patent/JP2002531473A/en
Priority to AU21754/00A priority patent/AU2175400A/en
Publication of WO2000033667A2 publication Critical patent/WO2000033667A2/en
Publication of WO2000033667A3 publication Critical patent/WO2000033667A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method for providing nutraceutical or phytoceutical benefits to a mammal, particularly a human, using cherry derivatives is described. A method for inhibiting oxidation in a living biological material is also described. A composition of anthocyanins, bioflavonoids, phenolics or mixtures thereof from cherries is used in the methods.
PCT/US1999/029440 1998-12-11 1999-12-10 Bioflavonoids, anthocyanins and phenol compounds from cherries as antioxidants WO2000033667A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
KR10-2001-7007239A KR100441927B1 (en) 1998-12-11 1999-12-10 A Formulation for Providing Phytoceutical or Nutraceutical Benefits Comprising Cherry Isolates
JP2000586180A JP2002531473A (en) 1998-12-11 1999-12-10 Use of cherry isolates that provide botanical or nutritional benefits of antioxidants
AU21754/00A AU2175400A (en) 1998-12-11 1999-12-10 Method for the use of cherry isolates providing antioxidant phytoceutical or nutraceutical benefits

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US11194598P 1998-12-11 1998-12-11
US60/111,945 1998-12-11
US12017899P 1999-02-16 1999-02-16
US60/120,178 1999-02-16
US09/317,310 US6423365B1 (en) 1998-12-11 1999-05-24 Method and compositions producing cherry derived products
US09/317,310 1999-05-24
US09/329,604 US6150408A (en) 1998-12-11 1999-06-10 Tart cherry compounds that have antioxidant activity and uses thereof
US09/329,604 1999-06-10
US34207699A 1999-06-28 1999-06-28
US09/342,076 1999-06-28

Publications (2)

Publication Number Publication Date
WO2000033667A2 WO2000033667A2 (en) 2000-06-15
WO2000033667A3 true WO2000033667A3 (en) 2000-08-31

Family

ID=27537321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/029440 WO2000033667A2 (en) 1998-12-11 1999-12-10 Bioflavonoids, anthocyanins and phenol compounds from cherries as antioxidants

Country Status (5)

Country Link
JP (1) JP2002531473A (en)
CN (1) CN100394916C (en)
AU (1) AU2175400A (en)
TW (1) TWI223982B (en)
WO (1) WO2000033667A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2358400A (en) * 1998-12-11 2000-06-26 Michigan State University Method and compositions for producing berry derived products
ATE358138T1 (en) * 2000-07-31 2007-04-15 World Resources Corp ANTIOXIDANTS FROM PLANT MATERIAL
US7306815B2 (en) * 2000-08-31 2007-12-11 Phenolics, Llc Compositions enriched in phenolic compounds and methods for producing the same
GB0127032D0 (en) 2001-11-09 2002-01-02 Medpalett Pharmaceuticals As Product
GB0316757D0 (en) * 2003-07-17 2003-08-20 Biochem Lab As Use
US7737121B2 (en) * 2004-07-29 2010-06-15 Board Of Trustees Of Michigan State University Insulin secretion by anthocyanins and anthocyanidins
EP2108692A1 (en) * 2008-04-11 2009-10-14 Brasseries Kronenbourg Method of obtaining concentrated extracts of polyphenols resulting from the brewing process
JP2015051934A (en) * 2013-09-05 2015-03-19 地方独立行政法人青森県産業技術センター Skin oxidative stress inhibitor
CN112624928B (en) * 2021-01-21 2023-03-17 黄河科技学院 Anticoagulant peach blossom effective component and application thereof
CN114317313B (en) * 2021-08-24 2022-08-09 清枫链食苏打饮品(吉林)有限公司 Application of sour cherry extract in preparation of product for reducing uric acid or inhibiting gout attack

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003146A1 (en) * 1990-08-20 1992-03-05 Ohlenschlaeger Gerhard Therapeutically active mixture of glutathion and anthocyan compounds
JPH06248267A (en) * 1993-02-24 1994-09-06 S I I Techno Res:Yugen New antioxidant
JPH06271850A (en) * 1993-03-23 1994-09-27 Nikken Food Kk Antioxidant obtained from natural product as raw material and its production
US5762936A (en) * 1996-09-04 1998-06-09 Biotics Research Corporation Antioxidant derived from lentil and its preparation and uses
DE19720767A1 (en) * 1997-05-07 1998-11-12 Protekum Umweltinstitut Gmbh O Use of e.g. p-hydroxybenzoic acid, gallic acid, vanillic acid, syringic acid, myricetin, quercetin and camphor oil

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003146A1 (en) * 1990-08-20 1992-03-05 Ohlenschlaeger Gerhard Therapeutically active mixture of glutathion and anthocyan compounds
JPH06248267A (en) * 1993-02-24 1994-09-06 S I I Techno Res:Yugen New antioxidant
JPH06271850A (en) * 1993-03-23 1994-09-27 Nikken Food Kk Antioxidant obtained from natural product as raw material and its production
US5762936A (en) * 1996-09-04 1998-06-09 Biotics Research Corporation Antioxidant derived from lentil and its preparation and uses
DE19720767A1 (en) * 1997-05-07 1998-11-12 Protekum Umweltinstitut Gmbh O Use of e.g. p-hydroxybenzoic acid, gallic acid, vanillic acid, syringic acid, myricetin, quercetin and camphor oil

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
BÖHM H ET AL: "Flavonole, Flavone und Anthocyane als natürliche Antioxidantien der Nahrung und ihre mögliche Rolle bei der Prävention prevention chronischer Erkrankungen", ZEITSCHRIFT FÜR ERNÄHRUNGSWISSENSCHAFT, vol. 37, June 1998 (1998-06-01), pages 147 - 163, XP000886715 *
DATABASE DISSERTATION ABSTRACTS DIALOG FILE 35: 1998; WANG, HAIBO: "ANTIOXIDANT AND ANTI-INFLAMMATORY COMPOUNDS IN TART CHERRIES (ANTHOCYANINS, PHENOLICS, FLAVONOIDS, BALATON, MONTMORENCY)", XP002137469 *
DATABASE WPI Section Ch Week 199440, Derwent World Patents Index; Class B05, AN 1994-322419, XP002137672 *
DATABASE WPI Section Ch Week 199443, Derwent World Patents Index; Class B02, AN 1994-347353, XP002137671 *
DISSERTATION; MICHIGAN STATE UNIVERSITY; EAST LANSING, MI, USA, (1998) AVAIL UMI; ORDER NO. AAD99-22386 (157 pages) *
I MARINA HEINONEN ET AL: "Antioxidant activity of berry phenolics on human low density lipoprotein and liposome oxidation", J AGRIC FOOD CHEM, vol. 46, 1998, pages 4107 - 4112, XP000886697 *
TSUDA T ET AL: "Antioxidative activity of the anthocyanin pigments cyanidin 3-O-beta-D-glucoside and cyanidin", J AGRIC FOOD CHEM, vol. 42, 1994, pages 2407 - 2410, XP000474636 *
WANG H ET AL: "Quantification and characterization of anthocyanins in balalon tart cherries", J AGRIC FOOD CHEM, vol. 45, 1997, pages 2556 - 2560, XP000886708 *
WANG HONG: "Oxygen radical absorbing capacy of anthocyanins", J AGRIC FOOD CHEM, vol. 45, 1997, pages 304 - 309, XP000886698 *

Also Published As

Publication number Publication date
TWI223982B (en) 2004-11-21
AU2175400A (en) 2000-06-26
CN100394916C (en) 2008-06-18
JP2002531473A (en) 2002-09-24
WO2000033667A2 (en) 2000-06-15
CN1334740A (en) 2002-02-06

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