+

WO2000024774A3 - Molecules apparentees au facteur de croissance - Google Patents

Molecules apparentees au facteur de croissance Download PDF

Info

Publication number
WO2000024774A3
WO2000024774A3 PCT/US1999/025458 US9925458W WO0024774A3 WO 2000024774 A3 WO2000024774 A3 WO 2000024774A3 US 9925458 W US9925458 W US 9925458W WO 0024774 A3 WO0024774 A3 WO 0024774A3
Authority
WO
WIPO (PCT)
Prior art keywords
growth factor
related molecules
factor related
gfrp
provides
Prior art date
Application number
PCT/US1999/025458
Other languages
English (en)
Other versions
WO2000024774A2 (fr
Inventor
Y Tom Tang
Henry Yue
Jennifer L Hillman
Neil C Corley
Karl J Guegler
Mariah R Baughn
Janice Au-Young
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Henry Yue
Jennifer L Hillman
Neil C Corley
Karl J Guegler
Mariah R Baughn
Au Young Janice
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Henry Yue, Jennifer L Hillman, Neil C Corley, Karl J Guegler, Mariah R Baughn, Au Young Janice filed Critical Incyte Pharma Inc
Priority to EP99956784A priority Critical patent/EP1127122A2/fr
Priority to JP2000578344A priority patent/JP2003524383A/ja
Priority to CA002347655A priority patent/CA2347655A1/fr
Priority to AU13316/00A priority patent/AU1331600A/en
Publication of WO2000024774A2 publication Critical patent/WO2000024774A2/fr
Publication of WO2000024774A3 publication Critical patent/WO2000024774A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des molécules apparentées au facteur de croissance (GFRP) humain et des polynucléotides qui identifient et codent pour lesdites GFRP; des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes; ainsi que des méthodes permettant de diagnostiquer, traiter ou prévenir les troubles associés à l'expression de GFRP.
PCT/US1999/025458 1998-10-28 1999-10-28 Molecules apparentees au facteur de croissance WO2000024774A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99956784A EP1127122A2 (fr) 1998-10-28 1999-10-28 Molecules apparentees au facteur de croissance
JP2000578344A JP2003524383A (ja) 1998-10-28 1999-10-28 成長因子関連分子
CA002347655A CA2347655A1 (fr) 1998-10-28 1999-10-28 Molecules apparentees au facteur de croissance
AU13316/00A AU1331600A (en) 1998-10-28 1999-10-28 Growth factor related molecules

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US18171198A 1998-10-28 1998-10-28
US09/181,711 1998-10-28
US20954798A 1998-12-11 1998-12-11
US09/209,547 1998-12-11
US31345799A 1999-05-17 1999-05-17
US09/313,457 1999-05-17

Publications (2)

Publication Number Publication Date
WO2000024774A2 WO2000024774A2 (fr) 2000-05-04
WO2000024774A3 true WO2000024774A3 (fr) 2000-12-28

Family

ID=27391452

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025458 WO2000024774A2 (fr) 1998-10-28 1999-10-28 Molecules apparentees au facteur de croissance

Country Status (5)

Country Link
EP (1) EP1127122A2 (fr)
JP (1) JP2003524383A (fr)
AU (1) AU1331600A (fr)
CA (1) CA2347655A1 (fr)
WO (1) WO2000024774A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2313778T3 (es) 1998-03-17 2009-03-01 Genentech, Inc. Polipeptidos homologos de vegf y de bmp1.
US6432673B1 (en) 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
DK1137773T3 (da) * 1998-12-07 2008-12-08 Zymogenetics Inc Væsktfaktorhomolog ZVEGF3
WO2001092301A2 (fr) * 2000-05-26 2001-12-06 Indiana University Advanced Research And Technology Institute Placc, nouvelle chimiokine c-c humaine isolee du placenta

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046281A2 (fr) * 1998-03-10 1999-09-16 Genentech, Inc. Nouveaux polypeptides et acides nucleiques les codant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046281A2 (fr) * 1998-03-10 1999-09-16 Genentech, Inc. Nouveaux polypeptides et acides nucleiques les codant

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRANDT R. ET AL.: "Identification and biological characterization of an epidermal growth factor-related protein: Cripto-1", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 25, 24 June 1994 (1994-06-24), pages 17320 - 17328, XP000910201 *
MARRA, M. ET AL.: "The WashU-HHMI mouse EST project", EMBL DATABASE, EMEST36.MMAA59621; ACCESSION-NO.: AA259621, 19 March 1997 (1997-03-19), XP002140754 *
RIDGE, R.J. AND SLOANE, N.H.: "Partial N-terminal amino acid sequence of the anti-neoplastic urinary protein (ANUP) and the anti-tumour effect of the N-terminal nonapeptide of the unique cytokine present in human granulocytes", CYTOKINE, vol. 8, no. 1, January 1996 (1996-01-01), pages 1 - 5, XP000915567 *
SOARES, M.B.: "Program for rat gene discovery and mapping", EMBL DATABASE, EMEST6.AI112088; ACCESSION-NO.: AI112088, 4 September 1998 (1998-09-04), XP002140755 *

Also Published As

Publication number Publication date
CA2347655A1 (fr) 2000-05-04
WO2000024774A2 (fr) 2000-05-04
EP1127122A2 (fr) 2001-08-29
AU2001213316A8 (en) 2008-04-24
AU1331600A (en) 2000-05-15
JP2003524383A (ja) 2003-08-19

Similar Documents

Publication Publication Date Title
WO1999061471A3 (fr) Proteines transmembranaires humaines
WO2001012662A3 (fr) Proteines associees a la membrane
WO1999036550A3 (fr) Molecules de proteases humaines
WO2000015793A3 (fr) Proteines gpcr humaines
WO2000018922A3 (fr) Proteines humaines associees a des glucides
WO2000034477A3 (fr) Proteines associees a des neurones
WO1999058692A3 (fr) Proteines associees a l'apoptose humaine
WO1999057144A3 (fr) Molecules de regulateur de transcription humaine
WO2000012703A3 (fr) Molecules associees au transport de proteines
WO2000026245A3 (fr) Proteines de transport membranaire
WO2000017355A3 (fr) Proteines humaines associees au cytosquelette
WO2000014251A3 (fr) Transferases humaines
WO2000005374A3 (fr) Molecules associees a une proliferation cellulaire
WO2000000594A3 (fr) Transferases humaines
WO1999061614A3 (fr) Proteines socs humaines
WO2000020604A3 (fr) Molecules d'oxydoreductase
WO2001032888A3 (fr) Molecules humaines de la transferase
WO2000031263A3 (fr) Proteines associees a la gtpase
WO1999041373A3 (fr) Molecules humaines associees au transport
WO1999057270A3 (fr) Molecules de recepteur humain
WO1999038981A3 (fr) Molecules de proteine kinase humaines
WO2000028045A3 (fr) Hydrolases humaines
WO2000023589A3 (fr) Proteines associees a la proliferation et a l'apoptose
WO2000065054A3 (fr) Proteines humaines associees aux membranes
WO1999049037A3 (fr) Molecules apparentees a la proteine-phosphatase

Legal Events

Date Code Title Description
ENP Entry into the national phase

Ref country code: AU

Ref document number: 2000 13316

Kind code of ref document: A

Format of ref document f/p: F

AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US US US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US US US US US US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 09830320

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2347655

Country of ref document: CA

Ref country code: CA

Ref document number: 2347655

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 578344

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 1999956784

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999956784

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1999956784

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载