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WO2000020590A3 - G-protein coupled receptor proteins - Google Patents

G-protein coupled receptor proteins Download PDF

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Publication number
WO2000020590A3
WO2000020590A3 PCT/US1999/023317 US9923317W WO0020590A3 WO 2000020590 A3 WO2000020590 A3 WO 2000020590A3 US 9923317 W US9923317 W US 9923317W WO 0020590 A3 WO0020590 A3 WO 0020590A3
Authority
WO
WIPO (PCT)
Prior art keywords
coupled receptor
protein coupled
receptor proteins
gcrp
provides
Prior art date
Application number
PCT/US1999/023317
Other languages
French (fr)
Other versions
WO2000020590A2 (en
Inventor
Y Tom Tang
Henry Yue
Preeti Lal
Olga Bandman
Janice Au-Young
Roopa Reddy
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Yalda Azimzai
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Henry Yue
Preeti Lal
Olga Bandman
Au Young Janice
Roopa Reddy
Neil C Corley
Karl J Guegler
Gina A Gorgone
Mariah R Baughn
Yalda Azimzai
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Henry Yue, Preeti Lal, Olga Bandman, Au Young Janice, Roopa Reddy, Neil C Corley, Karl J Guegler, Gina A Gorgone, Mariah R Baughn, Yalda Azimzai filed Critical Incyte Pharma Inc
Priority to AU64179/99A priority Critical patent/AU6417999A/en
Priority to EP99951820A priority patent/EP1119621A2/en
Priority to JP2000574685A priority patent/JP2003521870A/en
Priority to CA002345045A priority patent/CA2345045A1/en
Publication of WO2000020590A2 publication Critical patent/WO2000020590A2/en
Publication of WO2000020590A3 publication Critical patent/WO2000020590A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides human G-protein coupled receptor proteins (GCRP) and polynucleotides which identify and encode GCRP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of GCRP.
PCT/US1999/023317 1998-10-06 1999-10-06 G-protein coupled receptor proteins WO2000020590A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU64179/99A AU6417999A (en) 1998-10-06 1999-10-06 G-protein coupled receptor proteins
EP99951820A EP1119621A2 (en) 1998-10-06 1999-10-06 G-protein coupled receptor proteins
JP2000574685A JP2003521870A (en) 1998-10-06 1999-10-06 G protein-coupled receptor protein
CA002345045A CA2345045A1 (en) 1998-10-06 1999-10-06 G-protein coupled receptor proteins

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16721998A 1998-10-06 1998-10-06
US17221198A 1998-10-06 1998-10-06
US60/172,211 1998-10-06
US13358599P 1999-05-11 1999-05-11
US60/133,585 1999-05-11

Publications (2)

Publication Number Publication Date
WO2000020590A2 WO2000020590A2 (en) 2000-04-13
WO2000020590A3 true WO2000020590A3 (en) 2000-07-20

Family

ID=56289949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/023317 WO2000020590A2 (en) 1998-10-06 1999-10-06 G-protein coupled receptor proteins

Country Status (1)

Country Link
WO (1) WO2000020590A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000034473A2 (en) * 1998-12-10 2000-06-15 Zymogenetics, Inc. Seven transmembrane domain receptor zsig56
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
US7208280B2 (en) 1999-10-05 2007-04-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
DK2003202T3 (en) * 1999-10-05 2012-01-16 Agensys Inc G protein coupled receptor up-regulated in prostate cancer and its applications
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
US20030212255A1 (en) * 2000-07-26 2003-11-13 Muralidhara Padigaru Novel proteins and nucleic acids encoding same
JP2005501503A (en) * 2000-12-08 2005-01-20 インサイト・ゲノミックス・インコーポレイテッド G protein coupled receptor
WO2002092842A2 (en) * 2001-05-15 2002-11-21 Agensys, Inc. Nucleic acids and corresponsing proteins entitled 101p3a11 or phor-1 useful in treatment and detection of cancer
EP1465997A4 (en) * 2001-12-27 2006-05-24 Agy Therapeutics Inc Use of biomolecular targets in the treatment and visualization of tumors
DE10225443A1 (en) * 2002-06-08 2003-12-18 Aventis Pharma Gmbh Binding assay for identifying compounds that react with the mas-like-1 receptor, useful for treating cardiovascular disease, including activators and inhibitors
WO2004046315A2 (en) * 2002-11-14 2004-06-03 Slowave, Inc. Compositions and methods utilizing human gamma-hydroxybutyrate receptor
US20070106614A1 (en) 2003-11-20 2007-05-10 Koninklijke Philips Electronics N.V. Method and device for making available encoded digital data

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018651A1 (en) * 1994-12-16 1996-06-20 Smithkline Beecham Corporation Human somatostatin-like receptor
EP0805204A2 (en) * 1996-04-29 1997-11-05 Institut für Hormon- und Fortpflanzungsforschung GmbH Epididymis-specific receptor protein and its use
WO1999015551A1 (en) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Novel receptor
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018651A1 (en) * 1994-12-16 1996-06-20 Smithkline Beecham Corporation Human somatostatin-like receptor
EP0805204A2 (en) * 1996-04-29 1997-11-05 Institut für Hormon- und Fortpflanzungsforschung GmbH Epididymis-specific receptor protein and its use
WO1999015551A1 (en) * 1997-09-24 1999-04-01 Garvan Institute Of Medical Research Novel receptor
WO1999046281A2 (en) * 1998-03-10 1999-09-16 Genentech, Inc. Novel polypeptides and nucleic acids encoding the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMEST30 E.M.B.L. Databases; 4 October 1996 (1996-10-04), FUJIWARA T ET AL: "Human placenta cDNA 5'-end GEN-553A03", XP002130338 *
STADEL J M ET AL: "Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery", TRENDS IN PHARMACOLOGICAL SCIENCES,GB,ELSEVIER TRENDS JOURNAL, CAMBRIDGE, vol. 18, no. 11, November 1997 (1997-11-01), pages 430-437, XP004096215, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
WO2000020590A2 (en) 2000-04-13

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