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WO2000009071A3 - Nouvelle preparation a base de liposomes utilisable dans la traitement du cancer et d'autres maladies proliferantes - Google Patents

Nouvelle preparation a base de liposomes utilisable dans la traitement du cancer et d'autres maladies proliferantes Download PDF

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Publication number
WO2000009071A3
WO2000009071A3 PCT/IN1999/000037 IN9900037W WO0009071A3 WO 2000009071 A3 WO2000009071 A3 WO 2000009071A3 IN 9900037 W IN9900037 W IN 9900037W WO 0009071 A3 WO0009071 A3 WO 0009071A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
cancer
liposomal formulation
formulation useful
proliferation diseases
Prior art date
Application number
PCT/IN1999/000037
Other languages
English (en)
Other versions
WO2000009071A2 (fr
Inventor
Suresh Kumar Gupta
Shiladitya Sengupta
Thirumurthy Velpandian
Original Assignee
All India Inst Med
Suresh Kumar Gupta
Shiladitya Sengupta
Thirumurthy Velpandian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by All India Inst Med, Suresh Kumar Gupta, Shiladitya Sengupta, Thirumurthy Velpandian filed Critical All India Inst Med
Priority to AU16789/00A priority Critical patent/AU1678900A/en
Publication of WO2000009071A2 publication Critical patent/WO2000009071A2/fr
Publication of WO2000009071A3 publication Critical patent/WO2000009071A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur une nouvelle préparation à base de liposomes utilisable dans le traitement du cancer et d'autres maladies proliférantes plus stable et plus efficace et peu toxique consistant en un mélange d'au moins une épipodophyllotoxine ou ses analogues ou dérivés, en phospholipides, en stérols, en antioxydants et en cryoprotecteurs. L'invention porte également sur une trousse de liposomes utilisant ladite préparation et sur un procédé de traitement des animaux et des humains à l'aide de ladite préparation.
PCT/IN1999/000037 1998-08-11 1999-08-10 Nouvelle preparation a base de liposomes utilisable dans la traitement du cancer et d'autres maladies proliferantes WO2000009071A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU16789/00A AU1678900A (en) 1998-08-11 1999-08-10 A novel liposomal formulation useful in treatment of cancer and other proliferation diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2337DE1998 1998-08-11
IN2337/DEL/98 1998-08-11

Publications (2)

Publication Number Publication Date
WO2000009071A2 WO2000009071A2 (fr) 2000-02-24
WO2000009071A3 true WO2000009071A3 (fr) 2000-06-15

Family

ID=11092773

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN1999/000037 WO2000009071A2 (fr) 1998-08-11 1999-08-10 Nouvelle preparation a base de liposomes utilisable dans la traitement du cancer et d'autres maladies proliferantes

Country Status (2)

Country Link
AU (1) AU1678900A (fr)
WO (1) WO2000009071A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2393595A1 (fr) * 1999-12-10 2001-06-14 Gigi Chiu Compositions d'excipient a base de lipides ayant des fonctions de reaction au moyen d'une surface protegee
US8883856B2 (en) * 2000-02-28 2014-11-11 John Jackson Compositions and methods for the treatment of inflammatory diseases using topoisomerase inhibitors
US8658203B2 (en) 2004-05-03 2014-02-25 Merrimack Pharmaceuticals, Inc. Liposomes useful for drug delivery to the brain
EP4218730B1 (fr) 2004-05-03 2023-11-01 Ipsen Biopharm Ltd. Liposomes utiles pour l'administration de médicaments
EP1871343A2 (fr) 2005-04-12 2008-01-02 Wisconsin Alumni Research Foundation Composition micellaire polymere et medicament contenu dans celle-ci
EP2480207B1 (fr) 2009-09-25 2016-11-09 Wisconsin Alumni Research Foundation Encapsulation d'agents thérapeutiques dans des micelles
EP3362049A1 (fr) 2015-10-16 2018-08-22 Ipsen Biopharm Ltd. Stabilisation de compositions pharmaceutiques de camptothécine
CN111701026B (zh) * 2020-06-28 2022-10-21 吴燕 抗肿瘤的组合药物纳米载体及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0438091A2 (fr) * 1990-01-19 1991-07-24 Nippon Kayaku Kabushiki Kaisha Préparation lyophilisée contenant un dérivé 2-diméthylamino d'étoposide
US5534499A (en) * 1994-05-19 1996-07-09 The University Of British Columbia Lipophilic drug derivatives for use in liposomes
WO1997038731A1 (fr) * 1996-04-18 1997-10-23 The Regents Of The University Of California Immunoliposomes optimisant l'internalisation dans des cellules cibles
US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0438091A2 (fr) * 1990-01-19 1991-07-24 Nippon Kayaku Kabushiki Kaisha Préparation lyophilisée contenant un dérivé 2-diméthylamino d'étoposide
US5534499A (en) * 1994-05-19 1996-07-09 The University Of British Columbia Lipophilic drug derivatives for use in liposomes
US5741516A (en) * 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
WO1997038731A1 (fr) * 1996-04-18 1997-10-23 The Regents Of The University Of California Immunoliposomes optimisant l'internalisation dans des cellules cibles

Also Published As

Publication number Publication date
WO2000009071A2 (fr) 2000-02-24
AU1678900A (en) 2000-03-06

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