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WO2000008211A3 - Procedes et compositions de modulation d'hybridations 'sans discernement marginal' - Google Patents

Procedes et compositions de modulation d'hybridations 'sans discernement marginal' Download PDF

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Publication number
WO2000008211A3
WO2000008211A3 PCT/US1999/017650 US9917650W WO0008211A3 WO 2000008211 A3 WO2000008211 A3 WO 2000008211A3 US 9917650 W US9917650 W US 9917650W WO 0008211 A3 WO0008211 A3 WO 0008211A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
indiscriminant
hybridizations
marginally
Prior art date
Application number
PCT/US1999/017650
Other languages
English (en)
Other versions
WO2000008211A9 (fr
WO2000008211A2 (fr
Inventor
Michael J Lane
Albert S Benight
Brian D Faldasz
Original Assignee
Tm Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tm Technologies Inc filed Critical Tm Technologies Inc
Priority to EP99940875A priority Critical patent/EP1102865A2/fr
Priority to JP2000563833A priority patent/JP2002522047A/ja
Publication of WO2000008211A2 publication Critical patent/WO2000008211A2/fr
Publication of WO2000008211A3 publication Critical patent/WO2000008211A3/fr
Publication of WO2000008211A9 publication Critical patent/WO2000008211A9/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne le domaine de la biologie moléculaire, de la chimie des acides nucléiques et des diagnostics médicaux. Plus particulièrement, l'invention concerne des procédés et des compostions de stimulation de l'hybridation d'une sonde d'acide nucléique avec une séquence d'acide nucléique cible qui n'est par parfaitement appariée à la sonde.
PCT/US1999/017650 1998-08-04 1999-08-04 Procedes et compositions de modulation d'hybridations 'sans discernement marginal' WO2000008211A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99940875A EP1102865A2 (fr) 1998-08-04 1999-08-04 Procedes et compositions de modulation d'hybridations "sans discernement marginal"
JP2000563833A JP2002522047A (ja) 1998-08-04 1999-08-04 限界まで非弁別的なハイブリダイゼーションを調節する方法及び組成

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9531398P 1998-08-04 1998-08-04
US36608599A 1999-08-03 1999-08-03
US60/095,313 1999-08-03
US09/366,085 1999-08-03

Publications (3)

Publication Number Publication Date
WO2000008211A2 WO2000008211A2 (fr) 2000-02-17
WO2000008211A3 true WO2000008211A3 (fr) 2000-08-03
WO2000008211A9 WO2000008211A9 (fr) 2000-10-12

Family

ID=26790077

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017650 WO2000008211A2 (fr) 1998-08-04 1999-08-04 Procedes et compositions de modulation d'hybridations 'sans discernement marginal'

Country Status (3)

Country Link
EP (1) EP1102865A2 (fr)
JP (1) JP2002522047A (fr)
WO (1) WO2000008211A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7244570B2 (en) 1998-08-04 2007-07-17 Luminex Molecular Diagnostics, Inc. Methods and compositions for modulating “marginally indiscriminant” hybridizations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006679A1 (fr) * 1989-10-24 1991-05-16 Stratagene Procede ameliore d'hybridation des acides nucleiques utilisant une proteine monocatenaire liante de l'acide nucleique
WO1993015226A1 (fr) * 1992-01-28 1993-08-05 President And Fellows Of Harvard College Procede d'hybridation d'acide nucleique a l'aide de proteine se liant sur l'adn monocatenaire
US5527898A (en) * 1988-09-09 1996-06-18 Hoffmann-La Roche Inc. Detection of human papillomavirus by the polymerase chain reaction
WO1997008183A1 (fr) * 1995-08-25 1997-03-06 Lane Michael J Fractions de capture d'acide nucleique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527898A (en) * 1988-09-09 1996-06-18 Hoffmann-La Roche Inc. Detection of human papillomavirus by the polymerase chain reaction
WO1991006679A1 (fr) * 1989-10-24 1991-05-16 Stratagene Procede ameliore d'hybridation des acides nucleiques utilisant une proteine monocatenaire liante de l'acide nucleique
WO1993015226A1 (fr) * 1992-01-28 1993-08-05 President And Fellows Of Harvard College Procede d'hybridation d'acide nucleique a l'aide de proteine se liant sur l'adn monocatenaire
WO1997008183A1 (fr) * 1995-08-25 1997-03-06 Lane Michael J Fractions de capture d'acide nucleique

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CARPENTER W R ET AL.: "A transcriptionally amplified DNA probe assay with ligatable probes and immunochemical detection", CLINICAL CHEMISTRY, vol. 39, no. 9, 1993, pages 1934 - 1938, XP002137905 *
MANOS M M ET AL: "USE OF POLYMERASE CHAIN REACTION AMPLIFICATION FOR THE DETECTION OF GENITAL HUMAN PAPILLOMAVIRUSES", CANCER CELLS,US,COLD SPRING HARBOR, NY, no. 7, 1 January 1989 (1989-01-01), pages 209 - 214, XP000471675, ISSN: 1042-2196 *

Also Published As

Publication number Publication date
EP1102865A2 (fr) 2001-05-30
WO2000008211A9 (fr) 2000-10-12
WO2000008211A2 (fr) 2000-02-17
JP2002522047A (ja) 2002-07-23

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