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WO2000008178A3 - Molecules d'adn murin codant pour des polypeptides presentant des fonctions kinases - Google Patents

Molecules d'adn murin codant pour des polypeptides presentant des fonctions kinases Download PDF

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Publication number
WO2000008178A3
WO2000008178A3 PCT/US1999/017577 US9917577W WO0008178A3 WO 2000008178 A3 WO2000008178 A3 WO 2000008178A3 US 9917577 W US9917577 W US 9917577W WO 0008178 A3 WO0008178 A3 WO 0008178A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
dna molecules
molecules encoding
encoding polypeptides
murine dna
Prior art date
Application number
PCT/US1999/017577
Other languages
English (en)
Other versions
WO2000008178A2 (fr
Inventor
G Duke Virca
Timothy Andrew Bird
Dirk M Anderson
John S Marken
Original Assignee
Immunex Corp
G Duke Virca
Timothy Andrew Bird
Dirk M Anderson
John S Marken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunex Corp, G Duke Virca, Timothy Andrew Bird, Dirk M Anderson, John S Marken filed Critical Immunex Corp
Priority to EP99938964A priority Critical patent/EP1027441A2/fr
Priority to AU53338/99A priority patent/AU5333899A/en
Priority to JP2000563801A priority patent/JP2002524046A/ja
Publication of WO2000008178A2 publication Critical patent/WO2000008178A2/fr
Publication of WO2000008178A3 publication Critical patent/WO2000008178A3/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des polypeptides murins purifiés et isolés présentant une fonction kinase, les acides nucléiques codant pources polypeptides, des procédés de production de formes recombinantes de ces polypeptides, des anticorps produits contre ces polypeptides, et des peptides fragmentés dérivés de ces polypeptides. L'invention concerne également l'utilisation de ces polypeptides et de ces peptides fragmentés dans des réactions de phosphorylation et comme marqueurs de la masse moléculaire, ces polypeptides etpeptides fragmentés pouvant par ailleurs être utilisés pour réguler la fragmentation peptidique. L'invention concerne enfin des kits comprenant ces réactifs.
PCT/US1999/017577 1998-08-04 1999-08-04 Molecules d'adn murin codant pour des polypeptides presentant des fonctions kinases WO2000008178A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP99938964A EP1027441A2 (fr) 1998-08-04 1999-08-04 Molecules d'adn murin codant pour des polypeptides presentant des fonctions kinases
AU53338/99A AU5333899A (en) 1998-08-04 1999-08-04 Murine dna molecules encoding polypeptides having kinase functions
JP2000563801A JP2002524046A (ja) 1998-08-04 1999-08-04 キナーゼ作用を有するポリペプチドをコードするマウスdna分子

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US9526998P 1998-08-04 1998-08-04
US60/095,269 1998-08-04
US9997398P 1998-09-11 1998-09-11
US60/099,973 1998-09-11

Publications (2)

Publication Number Publication Date
WO2000008178A2 WO2000008178A2 (fr) 2000-02-17
WO2000008178A3 true WO2000008178A3 (fr) 2000-06-15

Family

ID=26790020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017577 WO2000008178A2 (fr) 1998-08-04 1999-08-04 Molecules d'adn murin codant pour des polypeptides presentant des fonctions kinases

Country Status (4)

Country Link
EP (1) EP1027441A2 (fr)
JP (1) JP2002524046A (fr)
AU (1) AU5333899A (fr)
WO (1) WO2000008178A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2331889A1 (fr) * 1998-06-16 1999-12-23 Sugen, Inc. Kinases en rapport avec nek et avec bub1
US6630335B1 (en) 2000-02-11 2003-10-07 Millennium Pharmaceuticals, Inc. 14171 protein kinase, a novel human protein kinase and uses thereof
US7241585B2 (en) 2000-02-11 2007-07-10 Millennium Pharmaceuticals, Inc. 14171 protein kinase, a novel human protein kinase and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BEN-DAVID Y. ET AL.: "A MAMMALIAN PROTEIN KINASE WITH POTENTIAL FOR SERINE/THREONINE AND TYROSINE PHOSPHORYLATION IS RELATED TO CELL CYCLE REGULATORS", EMBO JOURNAL,GB,OXFORD UNIVERSITY PRESS, SURREY, vol. 10, no. 2, pages 317-325, XP002053900, ISSN: 0261-4189 *

Also Published As

Publication number Publication date
EP1027441A2 (fr) 2000-08-16
WO2000008178A2 (fr) 2000-02-17
JP2002524046A (ja) 2002-08-06
AU5333899A (en) 2000-02-28

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