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WO2000006728A8 - Effecteurs de phosphorylation - Google Patents

Effecteurs de phosphorylation

Info

Publication number
WO2000006728A8
WO2000006728A8 PCT/US1999/017132 US9917132W WO0006728A8 WO 2000006728 A8 WO2000006728 A8 WO 2000006728A8 US 9917132 W US9917132 W US 9917132W WO 0006728 A8 WO0006728 A8 WO 0006728A8
Authority
WO
WIPO (PCT)
Prior art keywords
effectors
phsp
phosphorylation
provides
expression
Prior art date
Application number
PCT/US1999/017132
Other languages
English (en)
Other versions
WO2000006728A3 (fr
WO2000006728A2 (fr
Inventor
Jennifer L Hillman
Preeti Lal
Y Tom Tang
Neil C Corley
Karl J Guegler
Mariah R Baughn
Chandra Patterson
Olga Bandman
Janice Au-Young
Gina A Gorgone
Henry Yue
Yalda Azimzai
Roopa Reddy
Dyung Aina M Lu
Leo L Shih
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Preeti Lal
Y Tom Tang
Neil C Corley
Karl J Guegler
Mariah R Baughn
Chandra Patterson
Olga Bandman
Au Young Janice
Gina A Gorgone
Henry Yue
Yalda Azimzai
Roopa Reddy
Dyung Aina M Lu
Leo L Shih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Preeti Lal, Y Tom Tang, Neil C Corley, Karl J Guegler, Mariah R Baughn, Chandra Patterson, Olga Bandman, Au Young Janice, Gina A Gorgone, Henry Yue, Yalda Azimzai, Roopa Reddy, Dyung Aina M Lu, Leo L Shih filed Critical Incyte Pharma Inc
Priority to JP2000562510A priority Critical patent/JP2002526035A/ja
Priority to AU51349/99A priority patent/AU5134999A/en
Priority to CA002335644A priority patent/CA2335644A1/fr
Priority to EP99935987A priority patent/EP1100904A2/fr
Publication of WO2000006728A2 publication Critical patent/WO2000006728A2/fr
Publication of WO2000006728A3 publication Critical patent/WO2000006728A3/fr
Publication of WO2000006728A8 publication Critical patent/WO2000006728A8/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des effecteurs de phosphorylation humains (PHSP) et des polynucléotides identifiant et codant pour ces effecteurs. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne également des méthodes de diagnostic, de traitement et de prévention de troubles associés à l'expression des effecteurs de phosphorylation humains.
PCT/US1999/017132 1998-07-28 1999-07-28 Effecteurs de phosphorylation WO2000006728A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000562510A JP2002526035A (ja) 1998-07-28 1999-07-28 リン酸化エフェクター
AU51349/99A AU5134999A (en) 1998-07-28 1999-07-28 Phosphorylation effectors
CA002335644A CA2335644A1 (fr) 1998-07-28 1999-07-28 Effecteurs de phosphorylation
EP99935987A EP1100904A2 (fr) 1998-07-28 1999-07-28 Effecteurs de phosphorylation

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US15521398P 1998-07-28 1998-07-28
US12349498A 1998-07-28 1998-07-28
US15281498A 1998-09-14 1998-09-14
US15519698P 1998-09-14 1998-09-14
US15523998P 1998-10-14 1998-10-14
US17348298A 1998-10-14 1998-10-14
US10688998P 1998-11-03 1998-11-03
US10909398P 1998-11-19 1998-11-19
US11379698P 1998-12-22 1998-12-22
US22900599A 1999-01-12 1999-01-12
US60/155,239 1999-01-12
US60/109,093 1999-01-12
US60/155,233 1999-01-12
US60/155,213 1999-01-12
US60/113,796 1999-01-12
US60/106,889 1999-01-12
US60/155,196 1999-01-12

Publications (3)

Publication Number Publication Date
WO2000006728A2 WO2000006728A2 (fr) 2000-02-10
WO2000006728A3 WO2000006728A3 (fr) 2000-05-04
WO2000006728A8 true WO2000006728A8 (fr) 2001-07-05

Family

ID=27581006

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017132 WO2000006728A2 (fr) 1998-07-28 1999-07-28 Effecteurs de phosphorylation

Country Status (1)

Country Link
WO (1) WO2000006728A2 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482933B1 (en) 1998-02-06 2002-11-19 Millennium Pharmaceuticals, Inc. Molecules of the card-related protein family and uses thereof
US6033855A (en) 1998-02-06 2000-03-07 Millennium Pharmaceuticals, Inc. Genes encoding caspase recruitment domain polypeptides
US6869775B2 (en) 1998-02-06 2005-03-22 Millennium Pharmaceuticals, Inc. Card related protein and uses thereof
US6680167B2 (en) 1998-02-06 2004-01-20 Millennium Pharmaceuticals, Inc. Molecules of the card-related protein family and uses thereof
US6469140B1 (en) 1998-02-06 2002-10-22 Millennium Pharmaceuticals, Inc. Molecules of the card-related protein family and uses thereof
US6340576B1 (en) 1998-02-06 2002-01-22 Millennium Pharmaceuticals, Inc. Nucleic acid molecules related to card-4L and CARD-4S
US20030028004A1 (en) * 2000-12-22 2003-02-06 Millennium Pharmaceuticals, Inc. 68730 and 69112, protein kinase molecules and uses therefor
CA2479476C (fr) * 1999-03-08 2009-11-10 Genentech, Inc. Compositions et procedes destines au traitement de tumeur
AU4206700A (en) * 1999-04-07 2000-10-23 Ceptyr, Inc. Dsp-3 dual-specificity phosphatase
CA2367104A1 (fr) * 1999-04-07 2000-10-12 Ceptyr, Inc. Map kinase phosphatase a double specificite dsp-7
EP1180151A2 (fr) * 1999-05-28 2002-02-20 Sugen, Inc. Proteines kinases
AU5446900A (en) 1999-05-28 2000-12-18 Immunex Corporation Novel murine and human kinases
US6756196B2 (en) 1999-06-28 2004-06-29 Millennium Pharmaceuticals, Inc. Molecules of the card-related protein family and uses thereof
US6656698B1 (en) 1999-06-30 2003-12-02 Millennium Pharmaceuticals, Inc. 12832, a novel human kinase-like molecule and uses thereof
US6558903B1 (en) 1999-06-30 2003-05-06 Millennium Pharmaceuticals, Inc. Kinases and uses thereof
US7078210B2 (en) 1999-07-02 2006-07-18 Ceptyr, Inc. DSP-3 dual-specificity phosphatase
WO2001002581A1 (fr) * 1999-07-02 2001-01-11 Ceptyr, Inc. Phosphatase dsp-3 a double specificite
WO2001012819A2 (fr) * 1999-08-13 2001-02-22 Sugen, Inc. Nouvelles phosphatases de proteines et diagnostic et traitement des troubles lies a la phosphatase
EP1209231A4 (fr) * 1999-08-19 2003-01-15 Kurokawa Kiyoshi Proteine meg-1
US6900043B1 (en) 1999-09-21 2005-05-31 Amgen Inc. Phosphatases which activate map kinase pathways
WO2001059080A1 (fr) * 2000-02-11 2001-08-16 Millennium Pharmaceuticals, Inc. Proteine kinase 18477 et utilisations de celle-ci
US20020137712A1 (en) * 2000-09-25 2002-09-26 Millennium Pharmaceuticals, Inc. 69109, a novel human tyrosine phosphatase and uses therefor
JP2004510442A (ja) * 2000-10-03 2004-04-08 グラクソ　グループ　リミテッド 腫瘍マーカーおよび使用方法
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
WO2003000874A2 (fr) * 2001-06-25 2003-01-03 Bayer Aktiengesellschaft Regulation de la proteine kinase serine/threonine humaine nek3
US7858297B2 (en) 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
ES2337989T3 (es) 2001-12-18 2010-05-03 Endocube Sas Nuevas proteinas asociadas a la muerte de la familia thap y rutas par4 relacionadas implicadas en el control de la apoptosis.
JP2005514013A (ja) * 2001-12-19 2005-05-19 ミレニアム・ファーマシューティカルズ・インコーポレイテッド １４６５、１５８７、２１４６、２２０７、３２８３８、３３６、および５２９０８を使用して疼痛および有痛性障害を処置する際の方法および組成物
AU2003215460A1 (en) * 2002-03-28 2003-10-13 Qlt Inc. Cancer associated protein kinases and their uses
WO2004015076A2 (fr) * 2002-08-07 2004-02-19 Curagen Corporation Nouvelles proteines et acides nucleiques les codant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU723640B2 (en) * 1995-06-28 2000-08-31 Incyte Pharmaceuticals, Inc. A human map kinase homolog
US5648239A (en) * 1996-06-21 1997-07-15 Incyte Pharmaceuticals, Inc. Human camp-dependent protein kinase inhibitor homolog
US5863780A (en) * 1996-09-12 1999-01-26 Incyte Pharmaceuticals, Inc. Human Protein Kinases
WO1999004265A2 (fr) * 1997-07-17 1999-01-28 Ludwig Institute For Cancer Research Acides nucleiques et polypeptides associes au cancer

Also Published As

Publication number Publication date
WO2000006728A3 (fr) 2000-05-04
WO2000006728A2 (fr) 2000-02-10

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