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WO2000073328A3 - Constructions d'unc-5 et methodes de selection - Google Patents

Constructions d'unc-5 et methodes de selection Download PDF

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Publication number
WO2000073328A3
WO2000073328A3 PCT/EP2000/005108 EP0005108W WO0073328A3 WO 2000073328 A3 WO2000073328 A3 WO 2000073328A3 EP 0005108 W EP0005108 W EP 0005108W WO 0073328 A3 WO0073328 A3 WO 0073328A3
Authority
WO
WIPO (PCT)
Prior art keywords
unc
constructs
screening methods
protein
cdna
Prior art date
Application number
PCT/EP2000/005108
Other languages
English (en)
Other versions
WO2000073328A2 (fr
Inventor
Criekinge Wim Van
Ingele Roelens
Thierry Bogaert
Phillipe Verwaerde
Original Assignee
Devgen Nv
Criekinge Wim Van
Ingele Roelens
Thierry Bogaert
Phillipe Verwaerde
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Devgen Nv, Criekinge Wim Van, Ingele Roelens, Thierry Bogaert, Phillipe Verwaerde filed Critical Devgen Nv
Priority to AU49263/00A priority Critical patent/AU4926300A/en
Publication of WO2000073328A2 publication Critical patent/WO2000073328A2/fr
Publication of WO2000073328A3 publication Critical patent/WO2000073328A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne de nouvelles variantes épissées d'ADNc unc-5c humain et une séquence d'ADNc unc-5HS1 humain. L'invention concerne également des essais basés sur les interactions protéine-protéine entre la protéine UNC-5 et une variété de protéines interactives différentes.
PCT/EP2000/005108 1999-06-01 2000-06-02 Constructions d'unc-5 et methodes de selection WO2000073328A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU49263/00A AU4926300A (en) 1999-06-01 2000-06-02 Unc-5 constructs and screening methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9912755.7A GB9912755D0 (en) 1999-06-01 1999-06-01 UNC-5 constructs and screening methods
GB9912755.7 1999-06-01

Publications (2)

Publication Number Publication Date
WO2000073328A2 WO2000073328A2 (fr) 2000-12-07
WO2000073328A3 true WO2000073328A3 (fr) 2001-04-12

Family

ID=10854560

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005108 WO2000073328A2 (fr) 1999-06-01 2000-06-02 Constructions d'unc-5 et methodes de selection

Country Status (3)

Country Link
AU (1) AU4926300A (fr)
GB (2) GB9912755D0 (fr)
WO (1) WO2000073328A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1326971A2 (fr) * 2000-07-28 2003-07-16 Curagen Corporation Proteines et acides nucleiques codant pour elles
WO2002029038A2 (fr) * 2000-10-04 2002-04-11 Curagen Corporation Nouvelles proteines, acides nucleiques codant ces derniers et anticorps diriges contre ces proteines
WO2002033080A2 (fr) * 2000-10-16 2002-04-25 Bayer Aktiengesellschaft Regulation du recepteur humain membranaire liant la netrine unc5h-1
WO2003037172A2 (fr) * 2001-11-01 2003-05-08 Gpc Biotech Inc. Peptide se fixant aux cellules endotheliales pour diagnostic et therapie
EP2267153A1 (fr) * 2009-05-26 2010-12-29 Université Claude Bernard Lyon 1 Identification de la mutation du gène unc5c du récepteur de la nétrine-1 dans des cancers solides

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014424A1 (fr) * 1995-10-16 1997-04-24 The Regents Of The University Of California Moyens de criblage pour medicaments neurologiques
WO1998037085A1 (fr) * 1997-02-19 1998-08-27 The Regents Of The University Of California Recepteurs de netrine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997014424A1 (fr) * 1995-10-16 1997-04-24 The Regents Of The University Of California Moyens de criblage pour medicaments neurologiques
WO1998037085A1 (fr) * 1997-02-19 1998-08-27 The Regents Of The University Of California Recepteurs de netrine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ACKERMAN SUSAN L ET AL: "Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23.", GENOMICS, vol. 52, no. 2, 1998, pages 205 - 208, XP000946854, ISSN: 0888-7543 *
COLAVITA ANTONIO ET AL: "Suppressors of ectopic UNC-5 growth cone steering identify eight genes involved in axon guidance in Caenorhabditis elegans.", DEVELOPMENTAL BIOLOGY, vol. 194, no. 1, 1 February 1998 (1998-02-01), pages 72 - 85, XP000946782, ISSN: 0012-1606 *

Also Published As

Publication number Publication date
AU4926300A (en) 2000-12-18
GB2352448B (en) 2002-03-27
GB0013412D0 (en) 2000-07-26
GB9912755D0 (en) 1999-08-04
WO2000073328A2 (fr) 2000-12-07
GB2352448A (en) 2001-01-31

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