WO2000067731A3 - Utilisation de medicaments pour eviter la tolerance aux nitrates - Google Patents
Utilisation de medicaments pour eviter la tolerance aux nitrates Download PDFInfo
- Publication number
- WO2000067731A3 WO2000067731A3 PCT/DE2000/001413 DE0001413W WO0067731A3 WO 2000067731 A3 WO2000067731 A3 WO 2000067731A3 DE 0001413 W DE0001413 W DE 0001413W WO 0067731 A3 WO0067731 A3 WO 0067731A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- medicinal substance
- nitrate tolerance
- substance utilization
- preventing
- preventing nitrate
- Prior art date
Links
- 229910002651 NO3 Inorganic materials 0.000 title abstract 3
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 title abstract 3
- 239000012907 medicinal substance Substances 0.000 title 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU58020/00A AU5802000A (en) | 1999-05-05 | 2000-05-05 | Medicinal substance utilization for preventing nitrate tolerance |
EP00943550A EP1173214A2 (fr) | 1999-05-05 | 2000-05-05 | Utilisation de medicaments pour eviter la tolerance aux nitrates |
BG105955A BG105955A (bg) | 1999-05-05 | 2001-09-26 | Използване на лекарствени вещества за избягване на нитратния толеранс |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19920775.5 | 1999-05-05 | ||
DE19920775A DE19920775A1 (de) | 1999-05-05 | 1999-05-05 | Arzneistoffverwendung zur Vermeidung von Nitrattoleranz |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000067731A2 WO2000067731A2 (fr) | 2000-11-16 |
WO2000067731A3 true WO2000067731A3 (fr) | 2001-01-25 |
Family
ID=7907118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE2000/001413 WO2000067731A2 (fr) | 1999-05-05 | 2000-05-05 | Utilisation de medicaments pour eviter la tolerance aux nitrates |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1173214A2 (fr) |
AU (1) | AU5802000A (fr) |
BG (1) | BG105955A (fr) |
DE (1) | DE19920775A1 (fr) |
PL (1) | PL352024A1 (fr) |
WO (1) | WO2000067731A2 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6537992B2 (en) * | 2001-01-05 | 2003-03-25 | John D. Parker | Regulation of organic nitrate tolerance |
GB0909243D0 (en) * | 2009-05-29 | 2009-07-15 | Univ Dundee | Angina treatment |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3839826A1 (de) * | 1988-11-25 | 1990-05-31 | Henning Berlin Gmbh | Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikaemie und gicht |
-
1999
- 1999-05-05 DE DE19920775A patent/DE19920775A1/de not_active Withdrawn
-
2000
- 2000-05-05 AU AU58020/00A patent/AU5802000A/en not_active Abandoned
- 2000-05-05 WO PCT/DE2000/001413 patent/WO2000067731A2/fr not_active Application Discontinuation
- 2000-05-05 EP EP00943550A patent/EP1173214A2/fr not_active Withdrawn
- 2000-05-05 PL PL00352024A patent/PL352024A1/xx not_active Application Discontinuation
-
2001
- 2001-09-26 BG BG105955A patent/BG105955A/bg unknown
Non-Patent Citations (2)
Title |
---|
C.G.SOBEY E.A.: "Allopurinol and amlodipine improve coronary vasodilatation after myocardial ischaemia and reperfusion in anaesthetized dogs", BRITISH JOURNAL OF PHARMACOLOGY, vol. 108, no. 2, 1993, pages 342 - 347, XP000953125 * |
T.M.MILLAR E.A.: "Xanthine oxidoreductase catalyses the reduction of nitrates and nitrite to nitric oxide under hypoxic conditions", FEBS LETTERS, vol. 427, 1998, pages 225 - 228, XP002133526 * |
Also Published As
Publication number | Publication date |
---|---|
BG105955A (bg) | 2002-06-28 |
PL352024A1 (en) | 2003-07-14 |
AU5802000A (en) | 2000-11-21 |
EP1173214A2 (fr) | 2002-01-23 |
DE19920775A1 (de) | 2000-11-16 |
WO2000067731A2 (fr) | 2000-11-16 |
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