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WO2000066784A3 - Genes et proteines de tissu adipeux brun pouvant etre regules par l'hormone de croissance et applications de ceux-ci - Google Patents

Genes et proteines de tissu adipeux brun pouvant etre regules par l'hormone de croissance et applications de ceux-ci Download PDF

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Publication number
WO2000066784A3
WO2000066784A3 PCT/US2000/012145 US0012145W WO0066784A3 WO 2000066784 A3 WO2000066784 A3 WO 2000066784A3 US 0012145 W US0012145 W US 0012145W WO 0066784 A3 WO0066784 A3 WO 0066784A3
Authority
WO
WIPO (PCT)
Prior art keywords
adipose tissue
regulatable
growth hormone
brown adipose
corresponding proteins
Prior art date
Application number
PCT/US2000/012145
Other languages
English (en)
Other versions
WO2000066784A2 (fr
Inventor
John Joseph Kopchick
Yuesheng Li
Original Assignee
Univ Ohio
John Joseph Kopchick
Yuesheng Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Ohio, John Joseph Kopchick, Yuesheng Li filed Critical Univ Ohio
Priority to CA002373227A priority Critical patent/CA2373227A1/fr
Priority to US09/959,714 priority patent/US7060437B1/en
Publication of WO2000066784A2 publication Critical patent/WO2000066784A2/fr
Publication of WO2000066784A3 publication Critical patent/WO2000066784A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des gènes et des protéines de tissu adipeux brun pouvant être régulés par l'hormone de croissance, qui ont été identifiés. Ceux-ci peuvent être utilisés comme marqueurs diagnostiques de pathologies du tissu adipeux.
PCT/US2000/012145 1999-05-05 2000-05-05 Genes et proteines de tissu adipeux brun pouvant etre regules par l'hormone de croissance et applications de ceux-ci WO2000066784A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002373227A CA2373227A1 (fr) 1999-05-05 2000-05-05 Genes et proteines de tissu adipeux brun pouvant etre regules par l'hormone de croissance et applications de ceux-ci
US09/959,714 US7060437B1 (en) 1999-05-05 2000-05-05 Growth hormone-regulatable brown adipose tissue genes and proteins and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13267099P 1999-05-05 1999-05-05
US60/132,670 1999-05-05

Publications (2)

Publication Number Publication Date
WO2000066784A2 WO2000066784A2 (fr) 2000-11-09
WO2000066784A3 true WO2000066784A3 (fr) 2002-03-28

Family

ID=22455069

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/012145 WO2000066784A2 (fr) 1999-05-05 2000-05-05 Genes et proteines de tissu adipeux brun pouvant etre regules par l'hormone de croissance et applications de ceux-ci

Country Status (2)

Country Link
CA (1) CA2373227A1 (fr)
WO (1) WO2000066784A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001064902A2 (fr) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals Membres de la famille des transferases 46867 et leurs utilisations
AU2002304249A1 (en) 2001-06-11 2002-12-23 Kirin Beer Kabushiki Kaisha Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and dna coding for the same
JP5222138B2 (ja) * 2005-07-21 2013-06-26 バイオヴェンダー・ラボラトリー・メディシン・インコーポレイテッド 脂肪酸結合タンパク質の脂肪細胞型（ａ−ｆａｂｐ、ｆａｂｐ４、ｐ２）の濃度を測定する方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BJORN-HANSEN GOTZSCHE, L. S. ET AL.: "The influence of growth hormone and thyroxine on iodothyronine deiodinase activity in the liver, kidney and brown adipose tissue in hypophysectomized rats", ACTA ENDOCRINOLOGICA, vol. 125, no. 2, 1991, pages 219 - 226, XP001031115 *
CARVALHO, S. D. ET AL.: "Hormonal regulation of malic enzyme and glucose-6-phosphate dehydrogenase in brown adipose tissue", AM. J. PHYSIOL., vol. 264, no. 6, part 1, 1993, pages E874 - E881, XP001031127 *
CHARALAMPAKI, P. ET AL.: "Insulin-like growth factor binding protein-3 levels during early and late follow-up after surgery in acromegalic patients", EXP. CLIN. ENDOCRINOL. DIABETES, vol. 106, 1998, pages 130 - 134, XP001031229 *
NIJLAND, E. A. ET AL.: "A five day treatment with daily subcutaneous injections of growth hormone-releasing peptide-2 causes response attenuation and does not stimulate insulin-like growth factor-I secretion in healthy young men", EUROP. J. ENDOCRINOL., vol. 13, no. 4, 1998, pages 395 - 401, XP001031251 *

Also Published As

Publication number Publication date
WO2000066784A2 (fr) 2000-11-09
CA2373227A1 (fr) 2000-11-09

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