WO2000053034A1 - Agent annihilant l'oxygene actif - Google Patents
Agent annihilant l'oxygene actif Download PDFInfo
- Publication number
- WO2000053034A1 WO2000053034A1 PCT/JP1999/001397 JP9901397W WO0053034A1 WO 2000053034 A1 WO2000053034 A1 WO 2000053034A1 JP 9901397 W JP9901397 W JP 9901397W WO 0053034 A1 WO0053034 A1 WO 0053034A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- active oxygen
- syrup
- solvent
- locust bean
- annihilating
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
- A23L21/10—Marmalades; Jams; Jellies; Other similar fruit or vegetable compositions; Simulated fruit products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/206—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
- A23L29/238—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seeds, e.g. locust bean gum or guar gum
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Definitions
- the present invention relates to an active oxygen annihilating agent as a foodstuff additive and a method for the preparation thereof by utilizing an agricultural waste material as well as to a foodstuff containing the active oxygen annihilating agent.
- Active oxygen is a conceptual term which generally means several oxidative species including superoxide anions, oxygen radicals, hydroxyl radicals, hydrogen peroxide and the like having, when taken up from outside into or generated inside of a human body, adverse influences on the health condition of the human body such as peroxidation of lipids and mutation of DNAs to give increasing damages on living cells slowly but steadily disturbing normal activities to maintain the living body and finally leading to formation of malignant tumors and senescence acceleration. Accordingly, it is an important problem to reduce take-up amounts of active oxygen into human body.
- living bodies in general have a mechanism to render the active oxygen innoxious which suppresses appearance of the above mentioned unsound or diseased condition of the living body.
- This suppressing activity against the adverse effects of active oxygen is largely by virtue of the superoxide dismutase, referred to as SOD hereinafter, as a kind of enzymes, of which abundance level in the living body widely differs among individuals depending on the ages, races, living environments and other factors.
- SOD superoxide dismutase
- the overly active oxygen can be annihilated by factitiously supplying a substance which exhibits the same activity as the SOD from outside at least temporarily.
- Such a substance is usually referred to as an SOD-like substance.
- SOD-like substances including polyphenol compounds in red wine and cacao beans and catechms in green tea.
- the content of the SOD-like substance in these foodstuffs is so low that they are practically inapplicable to an acute symptom due to excess of active oxygen requiring an unduly large amount of the foodstuff intake.
- the SOD-like substances in foodstuffs cannot be concentrated without adversely affecting the tastmess or flavo ⁇ ness necessarily to degrade the quality of the foodstuff. Accordingly, the inventors have conducted extensive screening tests of a variety of natural products with an object to uncover a material exhibiting an SOD-like activity to direct their attention to locust bean pods.
- Locust bean is a leguminous plant having a scientific name of Ceratonia siliqua L. and growing in the Mediterranean coastal districts such as Italy, Spain and Portugal.
- the major application of locust beans is as a food additive including a powder obtained by pulverizing the seed albumen of locust beans to serve as a thickening and stabilizing agent called a locust bean gum.
- locust beans production of locust beans is necessarily accompanied by a corresponding amount of locust been pods as an agricultural waste material.
- locust bean pods as a by-product of locust beans, only a very small portion of the annual production of locust bean pods is utilized, for example in the United States, as a cocoa substitute or a coating material on confectionery and almost all of the locust bean pod production is merely discarded or, at best, utilized as a livestock feed.
- value-added utilization of locust bean pods is an important issue heretofore in the agricultural industry.
- the inventors have directed their attention to locust bean pods as one of the raw materials in their screening work to uncover an efficient and inexpensive source material of an SOD-like substance.
- the present invention accordingly provides a novel active oxygen annihilating agent having SOD-like activity which is an extract from locust bean pods in the form of a syrup or powder.
- the invention also provides a foodstuff admixed with the active oxygen annihilating agent.
- the above mentioned active oxygen annihilating agent having SOD-like activity is prepared from locust bean pods by a method which comprises the steps of: (a) crushing locust bean pods into particulates;
- the active oxygen annihilating agent in the form of a syrup or powder prepared in the above described manner contains, in addition to the active oxygen annihilating ingredient, a good amount of saccharides so that the syrup or powder can be added to a foodstuff of any types as a sweetening material besides the effect of active oxygen annihilation .
- the inventors conducted, as an outset, a chemical analysis of locust bean pods to determine various saccharide compounds including monosaccharides, disacchar ides and sugar alcohols.
- the results were as follows, where the saccharide contents per 100 g of dried locust bean pods are given in five ratings with the respective symbols of: (*) for less than 0.05 g; (**) for less than 0.3 g; (+) for 0.05 to 1 g; (++) for 1 to 10 g; and (+++) for more than 10 g.
- fructose (++) glucose ( ++ ) ; arabmose ( + ) ; xylose (+) ; mannose (+ ) ; and galactose (*)
- the saccharide constituent of locust bean pods consists mostly of sucrose, fructose and glucose so that the extract from locust bean pods has little problem on the health of human bodies even when taken in a relatively large amount. It is a quite unexpected discovery that, while absolutely no SOD-like activity can be noted in the germs and seed albumens of locust beans per se, very strong active oxygen annihilating activity is exhibited by the extract from locust bean pods. In the preparation of the inventive active oxygen annihilating agent, locust bean pods are subjected to solvent extraction by using an extractant solvent to give an extract solution.
- the extract solution as such exhibits a certain level of active oxygen annihilating activity
- the syrupy liquid can be freeze-dried or spray-dried to give an active oxygen annihilating agent in the form of a powder.
- locust bean pods are dried and crushed into particulates of a 0.01 to 1.5 mm or, preferably, smaller than 1.0 mm particle diameter.
- the particulates of locust bean pods are then brought into contact with an extractant solvent to effect extraction of the active substances to give an extract solution.
- Water is preferable as the extractant solvent although some organic solvents can be used for the purpose including alcoholic solvents such as methyl alcohol, ethyl alcohol, n-propyl alcohol, isopropyl alcohol, n-butyl alcohol, isobutyl alcohol, sec-butyl alcohol and tert-butyl alcohol, acetone, chloroform and n-hexane. These solvents can be used either singly or as a mixture of two kinds or more, if miscible. If necessary to shorten the extraction time, it is optional to conduct the extraction treatment at an elevated temperature.
- alcoholic solvents such as methyl alcohol, ethyl alcohol, n-propyl alcohol, isopropyl alcohol, n-butyl alcohol, isobutyl alcohol, sec-butyl alcohol and tert-butyl alcohol, acetone, chloroform and n-hexane. These solvents can be used either singly or as a mixture of two kinds or more, if miscible
- the amount of water is in the range from 5 to 50 times by weight of the particulate pods.
- the thus formed extraction mixture is kept under agitation at a temperature of 80 to 100 °C or, preferably, at about 100 °C for 1 to 60 minutes or, in most cases, for 5 to 20 minutes followed by filtration of the mixture to give a clear extract solution by removing the solid remnant.
- the extraction treatment is undertaken at room temperature, the extraction mixture is agitated for 3 to 24 hours followed by filtra-
- the extract solution obtained in the above described manner is then subjected to a concentrating treatment by evaporating at least a part of water as the solvent at a temperature of 60 to 100 °C or, preferably, at about 70 °C or under a reduced pressure to give a syrupy liquid which exhibits strong active oxygen annihilating activity.
- This syrupy liquid can be further subjected to a f reeze-drymg treatment or spray-drying treatment into a powdery form by completely removing the solvent.
- an alcoholic solvent has an advantage as compared with water that extraction of the saccharide materials from the locust bean pods can be decreased relative to the SOD-like active substances so that the active oxygen annihilating agent contains the SOD-like substances in an increased concentration relative to the saccharides. It is of course possible to control relative extraction of the saccharides and the SOD-like active substances by modifying the polarity of the extractant solvent with addition of water to an alcoholic solvent depending on the active oxygen annihilating agent as desired.
- particulates of locust bean pods are added to 5 to 20 times by weight of an extractant solvent, which may be absolute alcohol or a mixture of water and ethyl alcohol containing 60% by weight or less or, preferably, 30% by weight or less of water, and the extraction mixture is agitated at room temperature for 15 minutes to 48 hours or, preferably for at least 24 hours followed by filtration to give a clear extract solution by removing the solid remnant.
- the extract solution is subjected to a concentrating treatment by evaporating ethyl alcohol under reduced pressure to give a syrupy liquid which can be freeze-dried or spray-dried into a powder.
- the inventive active oxygen annihilating agent is prepared in the form of a dry powder by completely removing the solvent in the concentrating treatment in consideration of the physiological effects of the solvent on the human body.
- the preparation form of the inventive active oxygen annihilating agent which can be a syrupy liquid or a powder, naturally depends on the particularly intended application.
- a syrupy preparation can be diluted as such with cold or hot water or with an alcoholic drink to give a health beverage.
- a powder preparation can be sprinkled as such over a food or can be used as an additive ingredient in food processing.
- a 50 g portion of particulates of dried locust bean pods was added to 250 g of hot water to give an extraction mixture which was boiled for 15 minutes and then filtered by using filter paper to give a filtrate.
- This aqueous solution was subjected to the test of active oxygen annihilating activity by the method of electron spin resonance (ESR) spectrometry to find an activity of 1.7 x 10 3 U/g.
- ESR electron spin resonance
- the aqueous solution was concentrated by heating to evaporate water into the form of a thick syrup of pasty consistency having a saccharide content of about 80%, which was again subjected to the ESR measurement to obtain a very high activity value of 1.0 x 10 4 U/g.
- This syrup had a good taste with sweetness and flavor resembling black raw sugar and was delicious for eating in a manner like a conventional jam spread over bread or in place of a maple syrup on pan-cakes.
- a tasty drink with a flavor like cocoa could be obtained by dissolving the above prepared syrup in an appropriate volume of hot water under agitation.
- Example 2 A tasty drink with a flavor like cocoa could be obtained by dissolving the above prepared syrup in an appropriate volume of hot water under agitation.
- the extract syrup of locust bean pods prepared in Example 1 was diluted with hot water to make a diluted syrup having a final saccharide content of 50% by weight, from which a pasty sweet having a jam-like consistency was prepared in a formulation including 45% by weight of the syrup calculated as the saccharide content, 1% by weight of xanthan gum and 0.1% by weight of docosahexaenoic acid (DHA) , the balance being water.
- DHA docosahexaenoic acid
- This pasty sweet had a consistency suitable for spreading over bread and had a masking effect on the offensive taste inherent in DHA. Accordingly, the pasty sweet could be evaluated as a valuable health food having active oxygen annihilating activity derived from locust bean pods without distastef ulness due to DHA.
- Example 3 Example 3
- the locust bean pods extract in the form of a syrup of about 80% saccharide concentration prepared in the same manner as in Example 1 was diluted with hot water to give a diluted extract solution of 10% saccharide concentration.
- a 1000 g portion of the diluted extract solution was taken in a dish tray and frozen at -85 °C and subjected to freeze- drying for 24 hours in a vacuum freeze-dry apparatus to find that the syrup was completely dried into the form of a cake which could easily be disintegrated into a light and fluffy powder of very fine particles.
- a 100 g portion of an unsweetened yogurt was admixed with 3 g of the thus freeze-dried powder to find that the powder could readily be dissolved in the yogurt and had moderate sweetness.
- the extract from locust bean pods serves not only as an active oxygen annihilating agent but also as a sweetening agent.
- An active oxygen annihilating agent suitable as an additive in health food products can be produced from locust bean pods which hitherto had almost no way of utilization but to be discarded as an agricultural waste material.
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
L'invention concerne un nouvel agent annihilant l'oxygène actif se présentant sous la forme d'un sirop ou d'une poudre adapté en tant qu'additif à des aliments diététiques pour réduire les influences nocives de l'oxygène actif sur le corps humain. L'agent annihilant l'oxygène actif est préparé à partir de gousses de caroube ayant présenté jusqu'à maintenant peu d'utilisabilité et rejetées comme matière résiduelle agricole. Ainsi, les particules broyées de gousses de caroube sont soumises à un traitement d'extraction à l'aide d'eau et d'alcool éthylique et la solution extraite est concentrée par évaporation d'au moins une partie du solvant pour obtenir un sirop pouvant être lyophilisé ou séché par pulvérisation en une poudre. Le sirop peut être transformé, par exemple, en une confiture savoureuse que l'on peut tartiner sur du pain.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11063940A JP2000253852A (ja) | 1999-03-10 | 1999-03-10 | 食品用活性酸素消去剤及びそれを含む飲食物 |
JP11/63940 | 1999-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000053034A1 true WO2000053034A1 (fr) | 2000-09-14 |
Family
ID=13243860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP1999/001397 WO2000053034A1 (fr) | 1999-03-10 | 1999-03-19 | Agent annihilant l'oxygene actif |
Country Status (2)
Country | Link |
---|---|
JP (1) | JP2000253852A (fr) |
WO (1) | WO2000053034A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004057979A3 (fr) * | 2002-12-24 | 2005-09-01 | Nutrinova Gmbh | Aliment dietetique pour influencer positivement la sante cardio-vasculaire |
FR2905857A1 (fr) * | 2006-09-20 | 2008-03-21 | Chanel Parfums Beaute Soc Par | Utilisation d'un extrait de pulpe de caroube pour hydrate la peau |
WO2008034821A1 (fr) | 2006-09-20 | 2008-03-27 | Chanel Parfums Beaute | Utilisation cosmétique d'agents actifs qui stimulent l'expression de la matriptase |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114448560B (zh) | 2020-11-06 | 2024-08-27 | 深圳市中兴微电子技术有限公司 | 一种通信芯片及数据处理方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4843628B1 (fr) * | 1970-08-03 | 1973-12-19 | ||
US4427707A (en) * | 1981-04-11 | 1984-01-24 | Henkel Kgaa | Method for the production of food additives with improved taste |
US5776756A (en) * | 1995-08-31 | 1998-07-07 | Toyo Hakko Co., Ltd. | Fermentation compositions having superoxide dismutating activity and an antihypertensive agent for treatment of constipation each having the superoxide dismutating activity |
-
1999
- 1999-03-10 JP JP11063940A patent/JP2000253852A/ja active Pending
- 1999-03-19 WO PCT/JP1999/001397 patent/WO2000053034A1/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4843628B1 (fr) * | 1970-08-03 | 1973-12-19 | ||
US4427707A (en) * | 1981-04-11 | 1984-01-24 | Henkel Kgaa | Method for the production of food additives with improved taste |
US5776756A (en) * | 1995-08-31 | 1998-07-07 | Toyo Hakko Co., Ltd. | Fermentation compositions having superoxide dismutating activity and an antihypertensive agent for treatment of constipation each having the superoxide dismutating activity |
Non-Patent Citations (2)
Title |
---|
DATABASE EPODOC European Patent Office; 29 September 1993 (1993-09-29), DONGHUA INDUSTRY CORP SHENYANG, XP002123526 * |
DATABASE WPI Section Ch Derwent World Patents Index; Class D13, AN 1973-81324U, XP002123527 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004057979A3 (fr) * | 2002-12-24 | 2005-09-01 | Nutrinova Gmbh | Aliment dietetique pour influencer positivement la sante cardio-vasculaire |
FR2905857A1 (fr) * | 2006-09-20 | 2008-03-21 | Chanel Parfums Beaute Soc Par | Utilisation d'un extrait de pulpe de caroube pour hydrate la peau |
WO2008034821A1 (fr) | 2006-09-20 | 2008-03-27 | Chanel Parfums Beaute | Utilisation cosmétique d'agents actifs qui stimulent l'expression de la matriptase |
Also Published As
Publication number | Publication date |
---|---|
JP2000253852A (ja) | 2000-09-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2571291C (fr) | Procede d'extraction de jus de matieres vegetales contenant des glycosides terpeniques, et compositions en contenant | |
US6022573A (en) | Plant extract | |
US20020055620A1 (en) | Reduction inhibitory agent for active oxygen eliminating activity | |
EP2090181A1 (fr) | Matériaux thermoplastiques comportant des agents de transfert de charge et agents de génération de photo-acide | |
AU2005300770A1 (en) | Trehalose and/or isomaltulose as a carrier substance for dry flavoring formulations | |
DE60211632T2 (de) | Verwendung von Cyclotetrasaccharide zur Erhöhung der "Aktiven-Sauerstoff-Eliminierenden-Aktivität" | |
JP2007176919A (ja) | カルコン類化合物含有組成物 | |
WO2017150409A1 (fr) | Extrait aqueux dérivé du cacao, boisson/aliment contenant celui-ci, procédé de fabrication d'extrait de cacao, et procédé d'extraction de polyphénol | |
JP7580167B2 (ja) | タイタンビカスの新規用途 | |
WO2000053034A1 (fr) | Agent annihilant l'oxygene actif | |
KR100959620B1 (ko) | 저온 추출에 의한 가루형 차의 제조방법 | |
US3824323A (en) | Method of preparing taste-modifying composition | |
JP3004193B2 (ja) | 植物の緑色色素物質 | |
KR101793929B1 (ko) | 청포도, 미나리, 및 비트를 함유하는 항노화 기능성 과채음료 및 이의 제조방법 | |
JPH11263795A (ja) | 活性酸素消去能低減抑制剤 | |
JPH11103817A (ja) | 風味の改良されたグアバ葉エキスおよびその製造法 | |
DE2117381A1 (de) | Verfahren zur Gewinnung eines stabi len miraculinhaltigen Pulvers und dessen Verwendung sowie miracuhnhaltige ge schmacksverandernde Zusammensetzungen | |
JP2933774B2 (ja) | 葉類加工食品及びその製法 | |
KR20230080923A (ko) | 병풀 발효 추출물의 제조방법 및 그로부터 제조된 병풀 발효 추출물을 포함하는 항산화용 식품 조성물 | |
US4912089A (en) | Cariostatic materials and foods, and method for preventing dental caries | |
KR0126444B1 (ko) | 안토시아노사이드를 고함량으로 함유하는 와일드 블루베리(Wild blueberry)엑기스 건조분말의 제조방법 | |
CN115802902A (zh) | 交叉美拉德化植物底物 | |
JP3342235B2 (ja) | 動植物水溶性エキスの製法 | |
JP3188238B2 (ja) | 葉類加工食品及びその製法 | |
KR20210091614A (ko) | 흑마늘홍삼 음료 베이스 조성물, 이를 포함하는 혼합 음료 조성물 및 그 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
122 | Ep: pct application non-entry in european phase |