+

WO2000051684A3 - Regulateurs de transacylase independante de la coenzyme a comme medicaments psychotropes - Google Patents

Regulateurs de transacylase independante de la coenzyme a comme medicaments psychotropes Download PDF

Info

Publication number
WO2000051684A3
WO2000051684A3 PCT/GB2000/000779 GB0000779W WO0051684A3 WO 2000051684 A3 WO2000051684 A3 WO 2000051684A3 GB 0000779 W GB0000779 W GB 0000779W WO 0051684 A3 WO0051684 A3 WO 0051684A3
Authority
WO
WIPO (PCT)
Prior art keywords
coenzyme
regulators
psychotropic drugs
independent transacylase
transacylase
Prior art date
Application number
PCT/GB2000/000779
Other languages
English (en)
Other versions
WO2000051684A2 (fr
Inventor
David Frederick Horrobin
Original Assignee
Scarista Ltd
Horrobin David F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scarista Ltd, Horrobin David F filed Critical Scarista Ltd
Publication of WO2000051684A2 publication Critical patent/WO2000051684A2/fr
Publication of WO2000051684A3 publication Critical patent/WO2000051684A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne l'utilisation de médicaments capables d'inhiber une transacylase indépendante de la coenzyme A dans le traitement ou la production d'un médicament destiné au traitement de troubles psychiatriques.
PCT/GB2000/000779 1999-03-03 2000-03-03 Regulateurs de transacylase independante de la coenzyme a comme medicaments psychotropes WO2000051684A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904895.1A GB9904895D0 (en) 1999-03-03 1999-03-03 Regulators of coenzyme-A-independent transacylase as psychotropic drugs
GB9904895.1 1999-03-03

Publications (2)

Publication Number Publication Date
WO2000051684A2 WO2000051684A2 (fr) 2000-09-08
WO2000051684A3 true WO2000051684A3 (fr) 2001-01-04

Family

ID=10848886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/000779 WO2000051684A2 (fr) 1999-03-03 2000-03-03 Regulateurs de transacylase independante de la coenzyme a comme medicaments psychotropes

Country Status (2)

Country Link
GB (1) GB9904895D0 (fr)
WO (1) WO2000051684A2 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289204A2 (fr) * 1987-04-27 1988-11-02 Efamol Holdings Plc Compositions pharmaceutiques contenant des sels de lithium
WO1993016674A1 (fr) * 1992-02-11 1993-09-02 Smithkline Beecham Corporation INHIBITEURS DE LA CoA-IT ET DU PAF
WO1997004765A1 (fr) * 1995-07-25 1997-02-13 Smithkline Beecham Corporation INHIBITION D'UNE TRANSACYLASE INDEPENDANTE DE LA COENZYME A (CoA) ET APOPTOSE
WO1998016216A1 (fr) * 1996-10-11 1998-04-23 Scotia Holdings Plc Preparation pharmaceutique contenant de l'acide eicosapentanoïque et/ou de l'acide stearidonique
WO1998048788A1 (fr) * 1997-04-29 1998-11-05 Scotia Holdings Plc Traitement de la depression et de l'anxiete au moyen d'acide docosahexaenoique ou d'antioxydants naturels

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289204A2 (fr) * 1987-04-27 1988-11-02 Efamol Holdings Plc Compositions pharmaceutiques contenant des sels de lithium
WO1993016674A1 (fr) * 1992-02-11 1993-09-02 Smithkline Beecham Corporation INHIBITEURS DE LA CoA-IT ET DU PAF
WO1997004765A1 (fr) * 1995-07-25 1997-02-13 Smithkline Beecham Corporation INHIBITION D'UNE TRANSACYLASE INDEPENDANTE DE LA COENZYME A (CoA) ET APOPTOSE
WO1998016216A1 (fr) * 1996-10-11 1998-04-23 Scotia Holdings Plc Preparation pharmaceutique contenant de l'acide eicosapentanoïque et/ou de l'acide stearidonique
WO1998048788A1 (fr) * 1997-04-29 1998-11-05 Scotia Holdings Plc Traitement de la depression et de l'anxiete au moyen d'acide docosahexaenoique ou d'antioxydants naturels

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1989, VADDADI K S ET AL: "A DOUBLE-BLIND TRIAL OF ESSENTIAL FATTY ACID SUPPLEMENTATION IN PATIENTS WITH TARDIVE DYSKINESIA", XP002148486, Database accession no. PREV198988008362 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, HORROBIN D F ET AL: "Possible relevance of phospholipid abnormalities and genetic interactions in psychiatric disorders: The relationship between dyslexia and schizophrenia.", XP002148483, Database accession no. PREV199698702575 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, PEET MALCOLM ET AL: "Depleted red cell membrane essential fatty acids in drug-treated schizophrenic patients.", XP002148485, Database accession no. PREV199598430715 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, ADAMS PETER B ET AL: "Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression.", XP002148482, Database accession no. PREV199698797851 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; February 1998 (1998-02-01), CORRIGAN F M ET AL: "Abnormal content of n-6 and n-3 long-chain unsaturated fatty acids in the phosphoglycerides and cholesterol esters of parahippocampal cortex from Alzheimer's disease patients and its relationship to acetyl CoA content.", XP002148484, Database accession no. PREV199800266210 *
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 30, no. 2, February 1998 (1998-02-01), pages 197 - 207, ISSN: 1357-2725 *
JOURNAL OF PSYCHIATRIC RESEARCH, vol. 29, no. 3, 1995, pages 227 - 232, ISSN: 0022-3956 *
LIPIDS, vol. 31, no. SUPPL., 1996, pages S157 - S161, ISSN: 0024-4201 *
MEDICAL HYPOTHESES, vol. 45, no. 6, 1995, pages 605 - 613, ISSN: 0306-9877 *
PSYCHIATRY RESEARCH, vol. 27, no. 3, 1989, pages 313 - 324, ISSN: 0165-1781 *

Also Published As

Publication number Publication date
GB9904895D0 (en) 1999-04-28
WO2000051684A2 (fr) 2000-09-08

Similar Documents

Publication Publication Date Title
MXPA03007712A (es) Sales farmaceuticas.
TW200505483A (en) New medicament compositions based on anticholinergically-effective compounds and β-mimetics
AP2004002982A0 (en) Urea-compounds active as vanilloid receptor antagonists for the treatment of pain.
WO2004021968A3 (fr) Solution destinee a une application ungueale et peri-ungueale
WO2003009838A1 (fr) Utilisation de composes de stilbene dans la preparation de medicaments pour le traitement ou la prevention du diabete et des maladies associees au retrovirus
HK1064669A1 (en) Substituted 1-oxy-2,8-diaza-spiro Ä4,5Üdec-2-ene derivatives as medicaments for the treatment of pain.
YU82702A (sh) Ortosupstituisani amidi antranilne kiseline i njihova primena kao sredstva za lečenje
ZA200202521B (en) 2'-substituted 1,1'-biphenyl-2-carbonamides, method for the production thereof, use thereof as a medicament and pharmaceutical preprations containing said compounds.
YU7804A (sh) Stabilni polimorf flibanserina,postupak za njegovo dobijanje u industrijskim razmerama i njegova primena za pripremanje lekova
WO2000067847A3 (fr) Utilisation de ligands du recepteur de la dopamine d3 pour la production de medicaments servant au traitement de dysfonctionnements renaux
WO2001098279A3 (fr) Bis-arylsulfones
ZA200201788B (en) Substituted 1,5-dihydropyrrol-2-on derivatives as NMDA receptor antagonists for the treatment of pain.
SI1268522T1 (sl) Novi antagonisti lhrh, njihova priprava in uporaba kot zdravila
EP1440689A3 (fr) Traitement des troubles neurotiques
WO2003037863A3 (fr) Indoles substitues, procede pour leur preparation et leur utilisation pour lutter contre la douleur
WO2000064423A3 (fr) Utilisation du saredutant et de ses sels pharmaceutiquement acceptables dans le traitement ou la prevention des troubles de l'humeur d'adaptation et de l'anxiete-depression
BG104179A (en) Phanquinon administration for the treatment of the alzheimer's disease
HK1051692A1 (en) Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain.
UA86399C2 (ru) Применение 2,5 дигидроксибензолсульфоновой кислоты для изготовления лекарства, которые применяют для лечения болезней, зависимых от ангиогенеза
AU2001260110A1 (en) Novel LHRH-antagonists, Production and Use Thereof as Medicament
AU2002365288A1 (en) Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases
WO2000051684A3 (fr) Regulateurs de transacylase independante de la coenzyme a comme medicaments psychotropes
WO2000061125A3 (fr) L'osanetant dans le traitement des troubles de l'humeur
WO2001034124A3 (fr) Utilisation d'agonistes des recepteurs 5ht-1a a la serotonine pour le traitement de troubles respiratoires genetiques ou fonctionnels
WO2003000269A3 (fr) Nouvelle utilisation d'inhibiteurs de pde 10a

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载