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WO2000041537A3 - Utilisation de la proteine desert hedgehog - Google Patents

Utilisation de la proteine desert hedgehog Download PDF

Info

Publication number
WO2000041537A3
WO2000041537A3 PCT/US2000/000706 US0000706W WO0041537A3 WO 2000041537 A3 WO2000041537 A3 WO 2000041537A3 US 0000706 W US0000706 W US 0000706W WO 0041537 A3 WO0041537 A3 WO 0041537A3
Authority
WO
WIPO (PCT)
Prior art keywords
hedgehog protein
desert hedgehog
desert
dhh
administration
Prior art date
Application number
PCT/US2000/000706
Other languages
English (en)
Other versions
WO2000041537A2 (fr
Inventor
Brian Taylor Edmonds
Original Assignee
Lilly Co Eli
Brian Taylor Edmonds
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Brian Taylor Edmonds filed Critical Lilly Co Eli
Priority to AU27245/00A priority Critical patent/AU2724500A/en
Publication of WO2000041537A2 publication Critical patent/WO2000041537A2/fr
Publication of WO2000041537A3 publication Critical patent/WO2000041537A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des procédés permettant de traiter le phénomène de l'âge critique chez les hommes et autres troubles liés à la testostérone, qui consistent à administrer une quantité thérapeutiquement efficace de protéine Desert Hedgehog (Dhh-H), un fragment fonctionnel de cette protéine, ou un analogue de ladite protéine.
PCT/US2000/000706 1999-01-14 2000-01-12 Utilisation de la proteine desert hedgehog WO2000041537A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU27245/00A AU2724500A (en) 1999-01-14 2000-01-12 Use of desert hedgehog protein

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11593199P 1999-01-14 1999-01-14
US60/115,931 1999-01-14

Publications (2)

Publication Number Publication Date
WO2000041537A2 WO2000041537A2 (fr) 2000-07-20
WO2000041537A3 true WO2000041537A3 (fr) 2000-11-30

Family

ID=22364223

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/000706 WO2000041537A2 (fr) 1999-01-14 2000-01-12 Utilisation de la proteine desert hedgehog

Country Status (2)

Country Link
AU (1) AU2724500A (fr)
WO (1) WO2000041537A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844079A (en) * 1993-12-30 1998-12-01 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins, and uses related thereto
WO1999010004A2 (fr) * 1997-08-29 1999-03-04 Ontogeny, Inc. Regulation de tissus musculaires par des polypeptides 'hedgehog', et formulations et utilisations associees
WO1999039725A1 (fr) * 1998-02-06 1999-08-12 Eli Lilly And Company Proteines et acides nucleiques appartenant au herisson du desert

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844079A (en) * 1993-12-30 1998-12-01 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins, and uses related thereto
WO1999010004A2 (fr) * 1997-08-29 1999-03-04 Ontogeny, Inc. Regulation de tissus musculaires par des polypeptides 'hedgehog', et formulations et utilisations associees
WO1999039725A1 (fr) * 1998-02-06 1999-08-12 Eli Lilly And Company Proteines et acides nucleiques appartenant au herisson du desert

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BITGOOD M J ET AL: "SERTOLI CELL SIGNALING BY DESERT HEDGEHOG REGULATES THE MALE GERMLINE", CURRENT BIOLOGY,GB,CURRENT SCIENCE,, vol. 6, no. 3, 1 March 1996 (1996-03-01), pages 298 - 304, XP002072813, ISSN: 0960-9822 *

Also Published As

Publication number Publication date
WO2000041537A2 (fr) 2000-07-20
AU2724500A (en) 2000-08-01

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