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WO2000040607A3 - Adn codant les proteines tiam-2 et procede d'utilisation dudit adn - Google Patents

Adn codant les proteines tiam-2 et procede d'utilisation dudit adn Download PDF

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Publication number
WO2000040607A3
WO2000040607A3 PCT/US2000/000459 US0000459W WO0040607A3 WO 2000040607 A3 WO2000040607 A3 WO 2000040607A3 US 0000459 W US0000459 W US 0000459W WO 0040607 A3 WO0040607 A3 WO 0040607A3
Authority
WO
WIPO (PCT)
Prior art keywords
tiam2
metastasis
cell lymphoma
nucleotide exchange
exchange factor
Prior art date
Application number
PCT/US2000/000459
Other languages
English (en)
Other versions
WO2000040607A2 (fr
Inventor
David Duhl
Original Assignee
Chiron Corp
David Duhl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp, David Duhl filed Critical Chiron Corp
Priority to EP00902369A priority Critical patent/EP1144448A3/fr
Priority to AU24097/00A priority patent/AU2409700A/en
Priority to JP2000592315A priority patent/JP4707235B2/ja
Publication of WO2000040607A2 publication Critical patent/WO2000040607A2/fr
Publication of WO2000040607A3 publication Critical patent/WO2000040607A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La présente invention concerne des séquences nucléotidiques codant les protéines TIAM-2. L'invention comprend également les dosages diagnostiques, les vecteurs d'expression, les molécules antisens, les ribozymes, et les cellules hôtes utilisées pour exprimer le polypeptide codé par la séquence nucléotidique. La présente invention comprend également les revendications concernant la séquence polypeptidique codée par les séquences nucléotidiques.
PCT/US2000/000459 1999-01-06 2000-01-06 Adn codant les proteines tiam-2 et procede d'utilisation dudit adn WO2000040607A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00902369A EP1144448A3 (fr) 1999-01-06 2000-01-06 Adn codant les proteines tiam-2 et procede d'utilisation dudit adn
AU24097/00A AU2409700A (en) 1999-01-06 2000-01-06 Dna encoding t-cell lymphoma invasion and metastasis 2 and process for its use
JP2000592315A JP4707235B2 (ja) 1999-01-06 2000-01-06 Ｔｉａｍ２（ｔ細胞のリンパ腫の侵襲およびｍｅｔａｓｔａｓｉｓ２）ヌクレオチド交換因子

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22727899A 1999-01-06 1999-01-06
US09/227,278 1999-01-06

Publications (2)

Publication Number Publication Date
WO2000040607A2 WO2000040607A2 (fr) 2000-07-13
WO2000040607A3 true WO2000040607A3 (fr) 2001-11-01

Family

ID=22852486

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/000459 WO2000040607A2 (fr) 1999-01-06 2000-01-06 Adn codant les proteines tiam-2 et procede d'utilisation dudit adn

Country Status (4)

Country Link
EP (1) EP1144448A3 (fr)
JP (3) JP4707235B2 (fr)
AU (1) AU2409700A (fr)
WO (1) WO2000040607A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001293070A1 (en) * 2000-09-25 2002-04-08 Millennium Pharmaceuticals, Inc. 33521, a human guanine nucleotide exchange family member and uses thereof
EP1752040A1 (fr) * 2005-08-12 2007-02-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Identification de distorteurs du complex-t et leurs applications
US8679760B2 (en) * 2011-05-03 2014-03-25 National Cheng Kung University Biomarker and method for evaluating risk of proliferation, invasion, or metastasis of cancer
JP6675287B2 (ja) 2016-08-23 2020-04-01 日機装株式会社 流体殺菌装置

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046680A1 (fr) * 1996-06-05 1997-12-11 Chiron Corporation Adn codant la sequence dp-75 et procede d'utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046680A1 (fr) * 1996-06-05 1997-12-11 Chiron Corporation Adn codant la sequence dp-75 et procede d'utilisation

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHIU C.Y. ET AL.: "Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 61, no. 1, 1 October 1999 (1999-10-01), pages 66-73, XP000864676 *
CHIU C.Y. ET AL.: "Erratum: Cloning and characterization of T-cell lymphoma invasion and metastasis 2 (TIAM2), a novel guanine nucleotide exchange factor related to TIAM1.", GENOMICS, vol. 63, no. 3, 2000, pages 439, XP000864677 *
HOSHINO M. ET AL.: "Identification of the stef Gene That Encodes a Novel Guanine Nucleotide Exchange Factor Specific for Rac1", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 25, 18 June 1999 (1999-06-18), pages 17837 - 17844, XP002141545 *
HOSHINO M.: "Mus musculus Stef mRNA for sif and Tiam1-like exchange factor, complete cds", EMBL DATABASE ENTRY AB022915; ACCESSION NO. AB022915, 30 June 1999 (1999-06-30), XP002141546 *
LEEUWEN F.N. ET AL.: "The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho", JOURNAL OF CELL BIOLOGY, vol. 139, no. 3, 3 November 1997 (1997-11-03), pages 797 - 807, XP002141547 *

Also Published As

Publication number Publication date
JP4707235B2 (ja) 2011-06-22
JP2011083295A (ja) 2011-04-28
EP1144448A2 (fr) 2001-10-17
AU2409700A (en) 2000-07-24
JP2002538774A (ja) 2002-11-19
WO2000040607A2 (fr) 2000-07-13
EP1144448A3 (fr) 2002-03-06
JP2010233574A (ja) 2010-10-21

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