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WO1999038472A3 - Composition de gel de vasodilatation topique et ses methodes d'utilisation et de production - Google Patents

Composition de gel de vasodilatation topique et ses methodes d'utilisation et de production Download PDF

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Publication number
WO1999038472A3
WO1999038472A3 PCT/US1999/001830 US9901830W WO9938472A3 WO 1999038472 A3 WO1999038472 A3 WO 1999038472A3 US 9901830 W US9901830 W US 9901830W WO 9938472 A3 WO9938472 A3 WO 9938472A3
Authority
WO
WIPO (PCT)
Prior art keywords
vasodilatory
treatment
topical
production
methods
Prior art date
Application number
PCT/US1999/001830
Other languages
English (en)
Other versions
WO1999038472A2 (fr
Inventor
Oscar Hugh Campbell
Original Assignee
Seatrace Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seatrace Pharmaceuticals Inc filed Critical Seatrace Pharmaceuticals Inc
Priority to AU24790/99A priority Critical patent/AU2479099A/en
Publication of WO1999038472A2 publication Critical patent/WO1999038472A2/fr
Publication of WO1999038472A3 publication Critical patent/WO1999038472A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne une nouvelle composition comprenant un gel de vasodilatation s'utilisant en application topique pour la stimulation du flux sanguin, pour la visualisation des vaisseaux sanguins, pour le traitement de l'anorgasmie et pour le traitement de l'impuissance et d'autres formes d'insuffisance vasculaire; l'invention concerne également une méthode de préparation de ce gel de vasodilatation et une méthode d'utilisation de cette composition pour stimuler le flux sanguin, pour visualiser les vaisseaux sanguins, pour traiter l'anorgasmie et pour traiter l'impuissance et d'autres formes d'insuffisance vasculaire. La substance de vasodilatation préférée dans le gel de vasodilatation est la nitroglycérine.
PCT/US1999/001830 1998-01-28 1999-01-28 Composition de gel de vasodilatation topique et ses methodes d'utilisation et de production WO1999038472A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU24790/99A AU2479099A (en) 1998-01-28 1999-01-28 Topical vasodilatory gel composition and methods of use and production

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7290498P 1998-01-28 1998-01-28
US60/072,904980128 1998-01-28

Publications (2)

Publication Number Publication Date
WO1999038472A2 WO1999038472A2 (fr) 1999-08-05
WO1999038472A3 true WO1999038472A3 (fr) 2000-01-20

Family

ID=22110459

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/001830 WO1999038472A2 (fr) 1998-01-28 1999-01-28 Composition de gel de vasodilatation topique et ses methodes d'utilisation et de production

Country Status (2)

Country Link
AU (1) AU2479099A (fr)
WO (1) WO1999038472A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8927030B2 (en) 2003-07-09 2015-01-06 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251436B1 (en) 1995-09-29 2001-06-26 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
US6872384B1 (en) 1998-02-23 2005-03-29 Life Medical Sciences, Inc. Treatment of trauma
DE60022892T2 (de) 1999-10-21 2006-07-13 Kao Corp. Verfahren zur Enthaarung
JP2004506688A (ja) * 2000-08-23 2004-03-04 フェアーソン・メディカル・インコーポレーテッド 損傷、および他の適応症の治療
WO2006125123A2 (fr) 2005-05-19 2006-11-23 University Of Cincinnati Procedes pour le traitement d'infections des voies respiratoires chez un sujet utilisant du nitrite acidifie
US20090054497A1 (en) * 2007-08-21 2009-02-26 Nawaz Ahmad Methods for attaining enhanced sexual wellness using anhydrous compositions
US20090054498A1 (en) * 2007-08-21 2009-02-26 Nawaz Ahmad Anhydrous Compositions Useful for Attaining Enhanced Sexual Wellness
US20090197892A1 (en) * 2007-08-21 2009-08-06 Nawaz Ahmad Anhydrous compositions useful for attaining enhanced sexual wellness
DE202008007318U1 (de) * 2008-03-14 2008-07-31 G. Pohl-Boskamp Gmbh & Co. Kg Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat
US20100184870A1 (en) * 2008-03-14 2010-07-22 Rolf Groteluschen Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate
CA2806636C (fr) 2010-08-03 2018-01-23 G. Pohl-Boskamp Gmbh & Co. Kg Utilisation de trinitrate de glyceryle pour le traitement d'oedemes traumatiques
EP2678006B1 (fr) 2011-02-25 2015-12-30 G. Pohl-Boskamp GmbH & Co. KG Conditionnement de préparations pharmaceutiques solides contenant la substance active trinitrate de glycéryle
ES2617494T3 (es) 2012-05-31 2017-06-19 G. Pohl-Boskamp Gmbh & Co. Kg Inducción de arteriogénesis con un donador de óxido nítrico tal como nitroglicerina
US9248099B2 (en) 2012-05-31 2016-02-02 Desmoid Aktiengesellschaft Use of stabilized granules containing glyceryl trinitrate for arteriogenesis
EP2878310B1 (fr) 2013-11-29 2017-01-11 G. Pohl-Boskamp GmbH & Co. KG Composition aqueuse pulvérisable comprenant du trinitrate de glycéryle

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316887A (en) * 1977-11-07 1982-02-23 Toko Yakuhin Kogyo Kabushiki Kaisha Composition for topical application and method for preparing the same
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US5571794A (en) * 1995-06-22 1996-11-05 Frome; Bruce M. Non-invasive novel method fo cosmetic lip augmentation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316887A (en) * 1977-11-07 1982-02-23 Toko Yakuhin Kogyo Kabushiki Kaisha Composition for topical application and method for preparing the same
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US5571794A (en) * 1995-06-22 1996-11-05 Frome; Bruce M. Non-invasive novel method fo cosmetic lip augmentation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8927030B2 (en) 2003-07-09 2015-01-06 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US9387224B2 (en) 2003-07-09 2016-07-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Treatment of specific cardiovascular conditions with nitrite

Also Published As

Publication number Publication date
WO1999038472A2 (fr) 1999-08-05
AU2479099A (en) 1999-08-16

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