WO1999031036A3 - O-derivatives of halogenated diphenyl ether compounds - Google Patents
O-derivatives of halogenated diphenyl ether compounds Download PDFInfo
- Publication number
- WO1999031036A3 WO1999031036A3 PCT/EP1998/007997 EP9807997W WO9931036A3 WO 1999031036 A3 WO1999031036 A3 WO 1999031036A3 EP 9807997 W EP9807997 W EP 9807997W WO 9931036 A3 WO9931036 A3 WO 9931036A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diphenyl ether
- sulfo
- radical
- derivatives
- substituted
- Prior art date
Links
- USIUVYZYUHIAEV-UHFFFAOYSA-N diphenyl ether Chemical class C=1C=CC=CC=1OC1=CC=CC=C1 USIUVYZYUHIAEV-UHFFFAOYSA-N 0.000 title abstract 3
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 abstract 4
- 229910052801 chlorine Inorganic materials 0.000 abstract 3
- 239000000460 chlorine Substances 0.000 abstract 3
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 239000011737 fluorine Substances 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
- C07C25/02—Monocyclic aromatic halogenated hydrocarbons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/12—Esters of phosphoric acids with hydroxyaryl compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention describes O-derivatives of halogenated diphenyl ether compounds of formula (1), in which R1 and R2 independently of one another are F, Cl or Br; Y is a radical of formula (1a); (1b); (1c); (1d); (1e) or (1f); R3 is C1-C22alkyl; C1-C22alkoxy; phenyl; phenyl-C1-C4alkyl; --(CH2)p4-A+R5R6R7; the radical of formula (I); R4 C1-C22alkyl; R5, R6, R7 and R8 independently of one another are hydrogen; C1-C4alkyl; sulfo-C1-C4alkyl; or R5 and R6 together with A form a cyclic radical unsubstituted or substituted by sulfo groups; or R7 and R8 together with N form a cyclic radical unsubstituted or substituted by sulfo groups; A is N or P; Z1 is fluorine, chlorine, the radical of formula (1g); Z2 is fluorine, chlorine, C1-C22alkoxy, C1-C22alkylthio or C1-C22-monoalkylamino or C1-C22dialkylamino; each of which is unsubstituted or substituted by OH, NH2 or sulfo; C6-C12aryloxy, C6-C12arylthio or C6-C12monoarylamino or C6-C12diarylamino, each of which is unsubstituted or substituted by OH, NH2 or sulfo; m is from 1 to 3; n is 1 or 2; and p1, p2, p3, p4 and p5 independently of one another are 1-4. The diphenyl ether derivatives according to the invention have excellent antimicrobial properties and are stable to migration.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU20525/99A AU2052599A (en) | 1997-12-12 | 1998-12-09 | O-derivatives of halogenated diphenyl ether compounds |
| EP98965241A EP1042265A2 (en) | 1997-12-12 | 1998-12-09 | O-derivatives of halogenated diphenyl ether compounds |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97810977 | 1997-12-12 | ||
| EP97810977.5 | 1997-12-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1999031036A2 WO1999031036A2 (en) | 1999-06-24 |
| WO1999031036A3 true WO1999031036A3 (en) | 1999-11-04 |
Family
ID=8230519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP1998/007997 WO1999031036A2 (en) | 1997-12-12 | 1998-12-09 | O-derivatives of halogenated diphenyl ether compounds |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1042265A2 (en) |
| AU (1) | AU2052599A (en) |
| WO (1) | WO1999031036A2 (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6683056B2 (en) * | 2000-03-30 | 2004-01-27 | Bristol-Myers Squibb Company | O-aryl glucoside SGLT2 inhibitors and method |
| AUPQ780300A0 (en) * | 2000-05-23 | 2000-06-22 | Gillam, Ian Dr | Dosage formula/guidelines for a sports antioxidant |
| FR2839448A1 (en) * | 2002-05-07 | 2003-11-14 | Oreal | The cosmetic or pharmaceutical use of esters of triclosan and of other antibacterial compounds in controlled release compositions to treat infective skin conditions such as acne, dermatitis, hair loss, dandruff and folliculitis |
| EP1845087A1 (en) * | 2006-04-14 | 2007-10-17 | Mutabilis SA | Hydroxyphenyl derivatives and biological applications thereof |
| WO2008003606A1 (en) * | 2006-07-05 | 2008-01-10 | Ciba Holding Inc. | Dihalogeno-hydroxydiphenylether as antimicrobials in water treatment |
| WO2010042804A2 (en) | 2008-10-10 | 2010-04-15 | Ndsu Research Foundation | Zwitterionic/amphiphilic pentablock copolymers and coatings therefrom |
| US9272985B2 (en) | 2009-09-01 | 2016-03-01 | Fab Pharma S.A.S. | Antibacterial hydroxyphenyl compound |
| US20110171279A1 (en) * | 2009-11-02 | 2011-07-14 | Ndsu Research Foundation | Polyethylenimine biocides |
| EP2386589A1 (en) | 2010-04-23 | 2011-11-16 | Centre National de la Recherche Scientifique (C.N.R.S) | Novel antimicrobial composition, use and preparation thereof |
| WO2012177986A2 (en) * | 2011-06-22 | 2012-12-27 | Vyome Biosciences | Conjugate-based antifungal and antibacterial prodrugs |
| CN106349718B (en) * | 2016-10-25 | 2019-04-12 | 齐鲁工业大学 | A kind of preparation method of antibiotic property collagen |
| CN115536543B (en) * | 2022-11-10 | 2023-11-03 | 贵州大学 | A kind of triclosan compound containing isopropanolamine structure and its preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629477A (en) * | 1966-08-08 | 1971-12-21 | Geigy Chem Corp | Halogenated diphenyether-containing compositions and control of pests therewith |
| EP0761243A1 (en) * | 1995-09-08 | 1997-03-12 | Union Carbide Chemicals And Plastics Company, Inc. | Biostatic coatings and processes |
-
1998
- 1998-12-09 WO PCT/EP1998/007997 patent/WO1999031036A2/en not_active Application Discontinuation
- 1998-12-09 AU AU20525/99A patent/AU2052599A/en not_active Abandoned
- 1998-12-09 EP EP98965241A patent/EP1042265A2/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629477A (en) * | 1966-08-08 | 1971-12-21 | Geigy Chem Corp | Halogenated diphenyether-containing compositions and control of pests therewith |
| EP0761243A1 (en) * | 1995-09-08 | 1997-03-12 | Union Carbide Chemicals And Plastics Company, Inc. | Biostatic coatings and processes |
Non-Patent Citations (1)
| Title |
|---|
| B.CARTÉ ET AL.: "Polybrominated Diphenyl Ethers from Dysidea Herbacea, Dysidea Cholera and Phyllospongia Foliascens.", TETRAHEDRON., vol. 37, no. 13, 1981, OXFORD GB, pages 2335 - 2339, XP002065025 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2052599A (en) | 1999-07-05 |
| WO1999031036A2 (en) | 1999-06-24 |
| EP1042265A2 (en) | 2000-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1999031036A3 (en) | O-derivatives of halogenated diphenyl ether compounds | |
| PT1289992E (en) | NEW CRYSTALLINE FORM OF A COMPOUND OF TRIAZOLO (4,5-D) PYRIMIDINE | |
| TR200101567T2 (en) | New triazolo (4.5-D) pyrimidine compositions. | |
| NO970495L (en) | Arylthio compounds as anti-bacterial and antiviral agents | |
| ID28740A (en) | SEFEM COMPOUNDS CONTAINING IMIDAZO [4,5-b] PYRIDINIUMMETYL THAT HAS A WIDELY ANTIBACTERIAL SPECTRUM | |
| AU546360B2 (en) | Benzo(b)thiophenes, benzo(b)furans, thiochromans and chromans | |
| GB2346879A (en) | Preparation of 3-substituted adenines and imidazo pyridines | |
| SE8500307D0 (en) | NEW ANTIVIRUAL AGENTS | |
| HK1053653A1 (en) | Antitumoral analogs of et-743. | |
| MXPA02012752A (en) | Herbicidal agents. | |
| ATE183747T1 (en) | HALOGEN-FREE, CYCLIC, PHOSPHORUS CONTAINING FLAME RETARDANT COMPOUNDS | |
| CA2280039A1 (en) | Rinse added laundry additive compositions having color care agents | |
| UA35550C2 (en) | uracil Derivatives revealing herbicidal activity | |
| GR3004629T3 (en) | ||
| TR200002380T2 (en) | New triazolo (4,5-d) pyrimidine compounds | |
| DE60111774D1 (en) | ANTIBACTERIAL COMPOUNDS | |
| CA2336129A1 (en) | Ectoparasiticide agents | |
| SE9802574D0 (en) | Novel compounds | |
| GR81856B (en) | ||
| PT1338596E (en) | PROCESSES FOR THE PREPARATION OF ANTIBACTERIAL AGENTS OF THE CARBAPENEM TYPE | |
| EA200201209A1 (en) | ANTI-TUMOR ANALOGUES ET-743 | |
| BG103329A (en) | Bis(acridinecarboxamide) and bis(phenazinecarboxamide) as antitumour agents | |
| EP0579836A4 (en) | ||
| NO154228C (en) | METHYL CHLORIDE MIXTURE CONTAINING A TERTIATED AMINE AS A STABILIZER AGAINST DIVISION ON WATER. | |
| WO1999059996A8 (en) | Antitumour 1,5-diazaanthraquinones |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AK | Designated states |
Kind code of ref document: A2 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
| DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
| AK | Designated states |
Kind code of ref document: A3 Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW |
|
| AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
| REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
| WWE | Wipo information: entry into national phase |
Ref document number: 1998965241 Country of ref document: EP |
|
| WWE | Wipo information: entry into national phase |
Ref document number: 09555869 Country of ref document: US |
|
| NENP | Non-entry into the national phase |
Ref country code: KR |
|
| WWP | Wipo information: published in national office |
Ref document number: 1998965241 Country of ref document: EP |
|
| NENP | Non-entry into the national phase |
Ref country code: CA |
|
| WWW | Wipo information: withdrawn in national office |
Ref document number: 1998965241 Country of ref document: EP |