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WO1999015198A3 - Agents pour lutter contre la meningite purulente - Google Patents

Agents pour lutter contre la meningite purulente Download PDF

Info

Publication number
WO1999015198A3
WO1999015198A3 PCT/EP1998/006069 EP9806069W WO9915198A3 WO 1999015198 A3 WO1999015198 A3 WO 1999015198A3 EP 9806069 W EP9806069 W EP 9806069W WO 9915198 A3 WO9915198 A3 WO 9915198A3
Authority
WO
WIPO (PCT)
Prior art keywords
agents
bacterial meningitis
combating bacterial
combating
meningitis
Prior art date
Application number
PCT/EP1998/006069
Other languages
German (de)
English (en)
Other versions
WO1999015198A2 (fr
Inventor
Dirk Lorenzen
Frank Duex
Thomas Meyer
Gaby Haas
Original Assignee
Max Planck Gesellschaft
Dirk Lorenzen
Frank Duex
Thomas Meyer
Gaby Haas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Dirk Lorenzen, Frank Duex, Thomas Meyer, Gaby Haas filed Critical Max Planck Gesellschaft
Priority to CA002304615A priority Critical patent/CA2304615A1/fr
Priority to EP98952634A priority patent/EP1015021A2/fr
Priority to JP2000512567A priority patent/JP2001517637A/ja
Publication of WO1999015198A2 publication Critical patent/WO1999015198A2/fr
Publication of WO1999015198A3 publication Critical patent/WO1999015198A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21072—IgA-specific serine endopeptidase (3.4.21.72)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24013—IgA-specific metalloendopeptidase (3.4.24.13)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne de nouveaux agents pour lutter contre la méningite purulente.
PCT/EP1998/006069 1997-09-23 1998-09-23 Agents pour lutter contre la meningite purulente WO1999015198A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002304615A CA2304615A1 (fr) 1997-09-23 1998-09-23 Agents pour lutter contre la meningite purulente
EP98952634A EP1015021A2 (fr) 1997-09-23 1998-09-23 Agents pour lutter contre la meningite purulente
JP2000512567A JP2001517637A (ja) 1997-09-23 1998-09-23 細菌性髄膜炎に対する薬剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19741955.0 1997-09-23
DE19741955A DE19741955A1 (de) 1997-09-23 1997-09-23 Mittel gegen bakterielle Meningitis

Publications (2)

Publication Number Publication Date
WO1999015198A2 WO1999015198A2 (fr) 1999-04-01
WO1999015198A3 true WO1999015198A3 (fr) 1999-06-17

Family

ID=7843345

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/006069 WO1999015198A2 (fr) 1997-09-23 1998-09-23 Agents pour lutter contre la meningite purulente

Country Status (5)

Country Link
EP (1) EP1015021A2 (fr)
JP (1) JP2001517637A (fr)
CA (1) CA2304615A1 (fr)
DE (1) DE19741955A1 (fr)
WO (1) WO1999015198A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020043814A (ja) * 2018-09-19 2020-03-26 東ソー株式会社 無活性アルカリホスファターゼ

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011367A1 (fr) * 1989-03-17 1990-10-04 Mogens Kilian PROTEASES D'IMMUNOGLOBULINE A1 (PROTEASES IgA1), PROCEDE DE PRODUCTION PAR GENIE GENETIQUE DE CE TYPE D'ENZYME ET VACCINS CONTENANT LES ENZYMES AINSI QUE DES FRAGMENTS DE CELLES-CI POUR L'IMMUNISATION CONTRE LA MENINGITE BACTERIENNE AINSI QUE D'AUTRES MALADIES PROVOQUEES PAR DES BACTERIES PRODUCTRICES DE PROTEASES IgA1
WO1993010818A1 (fr) * 1991-12-04 1993-06-10 New England Medical Center Hospitals, Inc. Preparation lactee pour nouveau-nes et additif pour cette preparation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990011367A1 (fr) * 1989-03-17 1990-10-04 Mogens Kilian PROTEASES D'IMMUNOGLOBULINE A1 (PROTEASES IgA1), PROCEDE DE PRODUCTION PAR GENIE GENETIQUE DE CE TYPE D'ENZYME ET VACCINS CONTENANT LES ENZYMES AINSI QUE DES FRAGMENTS DE CELLES-CI POUR L'IMMUNISATION CONTRE LA MENINGITE BACTERIENNE AINSI QUE D'AUTRES MALADIES PROVOQUEES PAR DES BACTERIES PRODUCTRICES DE PROTEASES IgA1
WO1993010818A1 (fr) * 1991-12-04 1993-06-10 New England Medical Center Hospitals, Inc. Preparation lactee pour nouveau-nes et additif pour cette preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DUX F. ET AL: "Stimulation of cytokine production in human monocytes by neisserial IgA protease.", IMMUNOBIOLOGY, (1997) 197/2-4 (202-203), XP002098588 *

Also Published As

Publication number Publication date
WO1999015198A2 (fr) 1999-04-01
JP2001517637A (ja) 2001-10-09
EP1015021A2 (fr) 2000-07-05
CA2304615A1 (fr) 1999-04-01
DE19741955A1 (de) 1999-04-01

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