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WO1999011794A3 - New vrk1 kinase - Google Patents

New vrk1 kinase Download PDF

Info

Publication number
WO1999011794A3
WO1999011794A3 PCT/US1998/018524 US9818524W WO9911794A3 WO 1999011794 A3 WO1999011794 A3 WO 1999011794A3 US 9818524 W US9818524 W US 9818524W WO 9911794 A3 WO9911794 A3 WO 9911794A3
Authority
WO
WIPO (PCT)
Prior art keywords
vrk1
kinase
new
nvrk1
provides
Prior art date
Application number
PCT/US1998/018524
Other languages
French (fr)
Other versions
WO1999011794A2 (en
Inventor
Henry Yue
Preeti Lal
Neil C Corley
Original Assignee
Incyte Pharma Inc
Henry Yue
Preeti Lal
Neil C Corley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Henry Yue, Preeti Lal, Neil C Corley filed Critical Incyte Pharma Inc
Priority to AU93044/98A priority Critical patent/AU9304498A/en
Publication of WO1999011794A2 publication Critical patent/WO1999011794A2/en
Publication of WO1999011794A3 publication Critical patent/WO1999011794A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides a new VRK1 kinase (NVRK1) and polynucleotides which identify and encode NVRK1. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NVRK1.
PCT/US1998/018524 1997-09-04 1998-09-04 New vrk1 kinase WO1999011794A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU93044/98A AU9304498A (en) 1997-09-04 1998-09-04 New vrk1 kinase

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92346997A 1997-09-04 1997-09-04
US08/923,469 1997-09-04

Publications (2)

Publication Number Publication Date
WO1999011794A2 WO1999011794A2 (en) 1999-03-11
WO1999011794A3 true WO1999011794A3 (en) 1999-07-08

Family

ID=25448731

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/018524 WO1999011794A2 (en) 1997-09-04 1998-09-04 New vrk1 kinase

Country Status (2)

Country Link
AU (1) AU9304498A (en)
WO (1) WO1999011794A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4121155B2 (en) * 1996-12-27 2008-07-23 中外製薬株式会社 Novel serine / threonine kinase gene
US6677437B1 (en) 1996-12-27 2004-01-13 Chugai Seiyaku Kabushiki Kaisha Serine-threonine kinase gene
WO2001011086A2 (en) * 1999-08-11 2001-02-15 Eos Biotechnology, Inc. Methods of screening for angiogenesis modulators
WO2014160364A1 (en) * 2013-03-13 2014-10-02 Dana-Farber Cancer Institute, Inc. Methods of treating cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998029552A1 (en) * 1996-12-27 1998-07-09 Chugai Research Institute For Molecular Medicine, Inc. Novel serine-threonine kinase gene

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998029552A1 (en) * 1996-12-27 1998-07-09 Chugai Research Institute For Molecular Medicine, Inc. Novel serine-threonine kinase gene

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NEZU J. ET AL.: "Identification of two novel human putative serine/threonine kinases VRK1 and VR2 with structural similarity to vaccinia virus B1R kinase", GENOMICS, vol. 45, no. 2, 15 October 1997 (1997-10-15), pages 327 - 331, XP002096180 *
NEZU J. ET AL.: "VRK1, COMPLETE CDS", EMBL DATABASE, 1 May 1997 (1997-05-01), HEIDELBERG, DE, XP002096179 *

Also Published As

Publication number Publication date
WO1999011794A2 (en) 1999-03-11
AU9304498A (en) 1999-03-22

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