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WO1999008738A1 - Appareil permettant d'administrer a la demande un gaz respirable d'appoint et technique correspondante - Google Patents

Appareil permettant d'administrer a la demande un gaz respirable d'appoint et technique correspondante Download PDF

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Publication number
WO1999008738A1
WO1999008738A1 PCT/AU1998/000641 AU9800641W WO9908738A1 WO 1999008738 A1 WO1999008738 A1 WO 1999008738A1 AU 9800641 W AU9800641 W AU 9800641W WO 9908738 A1 WO9908738 A1 WO 9908738A1
Authority
WO
WIPO (PCT)
Prior art keywords
patient
breathable gas
primary
gas supply
gas
Prior art date
Application number
PCT/AU1998/000641
Other languages
English (en)
Inventor
John William Ernest Brydon
Peter John Deacon Wickham
Original Assignee
Resmed Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO8577A external-priority patent/AUPO857797A0/en
Priority claimed from AUPP2391A external-priority patent/AUPP239198A0/en
Application filed by Resmed Limited filed Critical Resmed Limited
Priority to JP2000509474A priority Critical patent/JP2001514941A/ja
Priority to EP98938520A priority patent/EP1011773A4/fr
Priority to AU87202/98A priority patent/AU8720298A/en
Publication of WO1999008738A1 publication Critical patent/WO1999008738A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/021Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes operated by electrical means
    • A61M16/022Control means therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/12Preparation of respiratory gases or vapours by mixing different gases
    • A61M16/122Preparation of respiratory gases or vapours by mixing different gases with dilution
    • A61M16/125Diluting primary gas with ambient air
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/201Controlled valves
    • A61M16/202Controlled valves electrically actuated
    • A61M16/203Proportional
    • A61M16/204Proportional used for inhalation control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0057Pumps therefor
    • A61M16/0066Blowers or centrifugal pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit

Definitions

  • the present invention relates to an apparatus and method for supplying on- demand additional breathable gas to a patient receiving a primary flow of breathable gas from a primary breathable gas supply.
  • the invention has been developed primarily to adapt gas supply apparatus designed for Continuous Positive Airway Pressure (CPAP) treatment of, for example, Obstructive Sleep Apnea (OS A), for suitability in treating other syndromes and diseases including, for example, Chronic Obstructive Pulmonary Disease (COPD), cystic fibrosis, emphysema and various other neurologic or other disorders of the respiratory system that require higher gas flow rates than typically provided by CPAP gas supply apparatus.
  • CPAP Continuous Positive Airway Pressure
  • OS A Obstructive Sleep Apnea
  • COPD Chronic Obstructive Pulmonary Disease
  • cystic fibrosis cystic fibrosis
  • emphysema emphysema
  • various other neurologic or other disorders of the respiratory system that require higher gas flow rates than typically provided by CPAP gas supply apparatus.
  • CPAP gas supply apparatus Treatment of OS A by CPAP gas supply apparatus involves the continuous delivery of air (or other breathable gas) pressurised above atmospheric pressure to a patient's airways, generally via a conduit and a nose and/or mouth mask.
  • the pressure of the gas delivered to the patient can be constant level, bi-level (in synchronism with patient inspiration and expiration) or auto setting in level.
  • Fig. 1 schematically shows a prior art apparatus 10 for supplying breathable gas to a patient 12 via a conduit 14 and a nose mask 16 used in, for example, CPAP treatment.
  • the apparatus 10 includes a flow generator 18 in the form of a motor and fan assembly whose power is provided by a drive means 20 which commonly consist of a brushless motor control circuit which drives power transistors connected to the motor windings.
  • the drive means 20 are controlled by an electronic or computerised control means 22.
  • the control means 22 causes the speed of the motor to be varied to control the pressure of the delivered gas.
  • the control means 22 can regulate a solenoid driver to regulate the gas pressure by spilling off excess gas via a solenoid controlled vent.
  • the control means 22 can be programmed by the clinician to deliver a single or preset pattern of sequential pressures, such as those mentioned above, in response to the patient's breathing pattern and desired treatment.
  • Such prior art apparatus may be unsuitable for treating patients with, for example, COPD as flow generators designed for CPAP treatment produce a maximum flow, without a significant drop in treatment pressure, of 100 1/min or less which may not completely satisfy the respiratory requirements of the impulsive inspirations of, for example, a COPD patient.
  • COPD sufferers have a significantly faster inspiration time compared to "normal" breathing and this short inspiration is often accompanied by a considerable increase in maximum inspiratory flow.
  • Conventional CPAP flow generators cannot meet this sudden increase in flow demand and as a consequence the pressure in the air delivery system falls when the patient requires gas at a higher pressure.
  • the present invention discloses an apparatus for supplying on-demand additional breathable gas to a patient receiving a primary flow of gas from a primary breathable gas supply, the apparatus including: a controllable secondary breathable gas source in selective fluid communication with the patient; and a control means adapted to activate said controllable secondary breathable gas source in response to receiving an input signal indicative of the primary gas supply being unable to meet patient inspiratory requirements.
  • the present invention discloses an apparatus for supplying breathable gas to a patient, the apparatus including a primary breathable gas source in fluid communication with a patient's airways; a controllable secondary breathable gas source in selective fluid communication with a patient's airways; and a control means adapted to activate said controllable secondary gas source in response to receiving an input signal indicative of said primary gas source being unable to meet patient inspiratory requirements.
  • the breathable gas is desirably air.
  • the primary breathable gas source preferably includes a flow generator in the form of a fan driven by an electric motor.
  • the controllable secondary gas source preferably includes a flow generator in the form of one of a fan driven by an electric motor, a pressurised gas storage chamber, a connection to a constant pressurised gas source, a positive displacement device or combinations thereof.
  • the positive displacement device is desirably a diaphragm substantially sealing a chamber in fluid communication with the patient, the diaphragm moving through said chamber in response to an electromagnetic actuator to supply the gas in the chamber to the patient.
  • control means input signal is a signal indicative of the primary flow generator reaching maximum output.
  • control means input signal is a signal indicative of the pressure of the gas supplied to the patient falling below a predetermined minimum level.
  • controllable or secondary gas source does not receive control signals from the primary gas source but from, for example, a pressure transducer or other device that measures the pressure in the patient gas supply conduit or mask.
  • control means input signal is a signal indicative of patient inspiration commencing, such as is indicated by a sudden rise in the flow of air supplied to the patient.
  • the present invention discloses a plurality of breathable gas supply apparatus in fluid communication with a common patient.
  • the gas supply apparatus are preferably connected in parallel.
  • the present invention discloses a method for supplying on- demand additional breathable gas to a patient receiving a primary flow of breathable gas, the method including the steps of: monitoring the primary flow of breathable gas supplied to the patient; and activating a controllable secondary breathable gas source in selective fluid communication with the patient when the monitoring indicates that the primary gas supply is unable to meet patient inspiratory requirements.
  • the present invention discloses a method for supplying breathable gas to a patient, the method including the steps of: supplying a primary flow of breathable gas to the patient; monitoring the primary flow of gas supplied to the patient; activating a controllable secondary breathable gas source in selective fluid communication with the patient when the monitoring indicates that the primary gas supply is unable to meet patient inspiratory requirements.
  • the secondary breathable gas source is activated when the monitoring step indicates the primary breathable gas supply is at maximum output.
  • the secondary breathable gas source is activated when the monitoring step indicates the pressure of the primary breathable gas supply is below a predetermined minimum level.
  • the pressure of the primary gas supply is preferably measured at a mask worn by the patient or a gas supply conduit connecting the mask to the primary breathable gas supply.
  • the secondary breathable gas source is activated when the monitoring step indicates the commencement of patient inspiration.
  • FIG. 1 is a schematic diagram of a prior art CPAP breathable gas supply apparatus
  • Fig. 2 is a schematic diagram of a first embodiment of an apparatus for supplying on-demand additional breathable gas
  • Fig. 3 is a schematic side diagram of a second embodiment of an apparatus for supplying on-demand additional breathable gas
  • Fig. 4 is a schematic diagram of a third embodiment of an apparatus for supplying on-demand additional breathable gas
  • Fig. 5 is a schematic diagram of a fourth embodiment of an apparatus for supplying on-demand additional breathable gas
  • Fig. 6 is a schematic diagram of a fifth embodiment of an apparatus for supplying on-demand additional breathable gas.
  • Figs. 7a to 7e are approximate plots of patient air flow rate, breath detection, primary flow generator output pressure, secondary flow generator output pressure and combined flow generator output pressure respectively between the time of inspiration and expiration.
  • FIG. 2 there is shown a first embodiment of an apparatus for supplying on-demand additional breathable gas in the form of a second breathable gas supply system 110 used in conjunction with a first conventional breathable gas supply apparatus 10, similar to that shown in Fig. 1.
  • the second breathable gas supply apparatus 110 is comprised of a flow generator 118 powered by a drive means 120 under control of a control means 122 incorporated into the gas supply apparatus 10.
  • the output of the second flow generator 118 is introduced into the patient gas supply conduit 14 through conduit branch 114.
  • control means 122 When the control means 122 senses that the flow generator 18 cannot meet patient inspiratory requirements, for example, by sensing a pressure drop of the supplied gas when expecting the gas pressure to rise, a signal is sent to the drive means 120 causing the flow generator 118 to be energised and thereby provide an almost instantaneous additional flow of gas to the patient 12 (not shown). Similarly, when control means 122 senses that additional gas is no longer required it de-energises the flow generator 118.
  • This embodiment allows treatment of patients whose inspiratory requirements exceed those of a conventional CPAP flow generator to be met by the addition a simple low cost motor, fan and driver assembly to a conventional apparatus.
  • a one-way valve is incorporated into the conduit branch 114 to stop gas from the first flow generator 18 being forced into the second flow generator 118 (rather than the patient) when the second flow generator 118 is not supplying gas.
  • Fig. 3 shows a second embodiment in which a second gas supply apparatus 210 includes a flow generator 218 constantly energised by a drive means 220.
  • fluid communication between the flow generator 218 and conduit branch 214 is selectively blocked by a valve 226 which is controlled by a control means 222.
  • the control means 222 senses that the patient's inspiratory requirements are not being met, it opens valve 226 to allow additional gas to be supplied through branch conduit 214 into the main conduit 14 and so to the patient.
  • the control means 222 senses that the patient's inspiratory needs have been met it closes the valve 226.
  • a pneumatic reservoir 228 is interposed between the flow generator 218 and the valve 226, as shown.
  • the reservoir 228 is continually pressurised by the flow generator 218 and when the control means 222 opens the valve 226 a bolus of high pressure gas is able to be delivered to meet the instantaneous inspiratory demand of the patient.
  • the flow generator 218 and drive means 220 are replaced with a high pressure oxygen or compressed air feed, for example from an external source such as a compressed gas storage tank or the internal gas supply of a hospital ward, and directly connected to the valve 226 or the reservoir 228, as the case may be.
  • control means 322b of the second apparatus 310 receives control signals from the control means 322a of the primary apparatus 10.
  • the control means 322a provides a signal to the control means 322b causing the second drive means 320 to energise the second flow generator 318 and thereby causing additional gas flow through the branch conduit 314 into the primary conduit 14 and so to the patient 12.
  • the secondary gas supply apparatus acts automatically as a slave unit due to the connection of the second control means 322b to the first control means 322a.
  • Fig. 5 shows a fourth embodiment in which a second gas supply apparatus 410 receives control signals from a control means 422 incorporating a differential pressure transducer.
  • the transducer receives an indication of pressure from either side of a flow restrictor 430 via pressure tubing 432.
  • the control means 422 causes drive means 420 to energise flow generator 418 thereby providing additional gas supply.
  • the control means 422 is programmed to provide additional gas flow when the pressure drop across the flow restrictor 430 is less than about, for example, 0.5 cm H2O.
  • the flow generator 418 is deactivated when the pressure transducer of the control system 422 indicates the pressure in the patient supply conduit 14 is above this level or, alternatively, after a predetermined time has elapsed.
  • Fig. 6 shows a fifth embodiment with a second gas supply apparatus 510 comprising a chamber 540, a diaphragm 542 and an electromagnetic actuator 544.
  • the apparatus 510 is similar to a loudspeaker mounted within an enclosure.
  • This embodiment also has a control means 522 which utilises a differential pressure transducer 520 connected either side of restrictor 530 by tubing 532.
  • the control means 522 energises the electromagnetic actuator 544 to drive the ⁇ o diaphragm 542 across the chamber 540 thereby forcing the volume of shaded air 546 into the patient's gas supply conduit 14 to supplement the primary gas supply from the primary flow generator 10.
  • a flow restrictor 548 is provided to stop the additional gas from being forced into the primary flow generator 10 instead of the patient.
  • a one-way 15 valve can also be used for this purpose.
  • Line 600 shows the patient flow rate (F) changing from negative to positive at the beginning of inspiration Ti and vice-versa at the start of expiration Te.
  • Line 610 shows the pressure transducer output becoming high at Ti indicating inspiration and becoming low at Te indicating expiration.
  • 25 Line 620 shows the pressure (P) of the primary gas supply apparatus 10 increase to full flow as the fan undergoes finite acceleration between no flow at 621 and full flow at 622.
  • Line 630 shows the pressure of the second gas supply apparatus after energisation at Ti and de-energisation at Te.
  • Line 640 shows the sum of 620 and 630 and demonstrates how the fifth embodiment more quickly achieves full pressure to satisfy patient inspiration demand compared to that of the fan alone indicated by line 620 of Fig. 7c.
  • An advantage of the above-described embodiments of the invention is that the first or primary gas supply apparatus requires minimal modification to work in conjunction with the additional gas supply apparatus, especially in relation to the fifth embodiment which is operatively connected to the patient gas supply conduit or mask and not the primary gas supply apparatus.
  • the primary gas supply apparatus can also be of largely conventional CPAP design thereby reducing inventory.
  • additional flow generator(s) can be adapted to function with CPAP flow generators produced by various different manufacturers, not just those produced by the same manufacturer of the primary flow generator.
  • the invention is not limited to only a first and a second gas supply apparatus and that multiple gas supply apparatus may be connected in accordance with the invention with either a control system activating all the other flow generators when the flow provided by the first is insufficient or, for example, successively energising additional flow generators upon sensing the flow generator, or flow generators, already energised is/are providing insufficient flow.

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  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Abstract

Cette invention a trait à un appareil (10) ainsi qu'à la technique correspondante permettant d'administrer à la demande un gaz respirable d'appoint à un patient auquel est déjà administré un premier gaz respirable sortant d'un dispositif principal d'alimentation prévu à cet effet (10). Cet appareil comporte une source de gaz pouvant être commandée (118), en communication fluidique sélective avec le patient (12), ainsi qu'un système de commande (122) conçu pour mettre en fonctionnement cette source (118) à réception d'un signal d'entrée indiquant que le dispositif principal d'alimentation (10) n'est plus à même de subvenir aux besoins respiratoires du patient. La technique consiste à surveiller le dispositif d'alimentation en gaz respirable (10) et à faire fonctionner la source de gaz pouvant être commandée (118) lorsque le système de surveillance signale l'incapacité du premier dispositif d'alimentation à subvenir aux besoins respiratoires du patient.
PCT/AU1998/000641 1997-08-14 1998-08-13 Appareil permettant d'administrer a la demande un gaz respirable d'appoint et technique correspondante WO1999008738A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2000509474A JP2001514941A (ja) 1997-08-14 1998-08-13 オンディマンドの追加呼吸に適したガスを供給するための装置及び方法
EP98938520A EP1011773A4 (fr) 1997-08-14 1998-08-13 Appareil permettant d'administrer a la demande un gaz respirable d'appoint et technique correspondante
AU87202/98A AU8720298A (en) 1997-08-14 1998-08-13 An apparatus and method for supplying on-demand additional breathable gas

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPO8577 1997-08-14
AUPO8577A AUPO857797A0 (en) 1997-08-14 1997-08-14 An apparatus for supplying on-demand additional breathable gas
AUPP2391 1998-03-13
AUPP2391A AUPP239198A0 (en) 1998-03-13 1998-03-13 An apparatus for supplying on-demand additional breathable gas ii

Publications (1)

Publication Number Publication Date
WO1999008738A1 true WO1999008738A1 (fr) 1999-02-25

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Family Applications (1)

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PCT/AU1998/000641 WO1999008738A1 (fr) 1997-08-14 1998-08-13 Appareil permettant d'administrer a la demande un gaz respirable d'appoint et technique correspondante

Country Status (3)

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EP (1) EP1011773A4 (fr)
JP (1) JP2001514941A (fr)
WO (1) WO1999008738A1 (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1219313A1 (fr) * 2000-12-29 2002-07-03 Instrumentarium Corporation Dispositif à projection de liquide et soupape à magnéto-matériau à mémoire de forme
US6910484B1 (en) * 1999-05-10 2005-06-28 Maquet Critical Care Ab Constant pressure generator
US7077131B2 (en) 2000-10-19 2006-07-18 Mallinckrodt, Inc. Ventilator with dual gas supply
EP2842587A1 (fr) 2013-08-27 2015-03-04 Eove Appareil d'assistance respiratoire pour des personnes souffrant de troubles respiratoires et procédé de ventilation mis en oeuvre par ledit appareil
US20160279362A1 (en) * 2015-03-24 2016-09-29 Ventec Life Systems, Inc. Ventilator with integrated oxygen production
US9895504B2 (en) * 2011-02-08 2018-02-20 Neores Ab System and device for neonatal resuscitation and initial respiratory support
DE102005031808B4 (de) 2005-04-22 2018-08-16 Löwenstein Medical Technology S.A. Vorrichtung zur Drucksteuerung bei Beatmungsgeräten
EP3386576A4 (fr) * 2015-12-10 2019-08-14 ResMed Pty Ltd Procédés et appareil de traitement respiratoire
US10773049B2 (en) 2016-06-21 2020-09-15 Ventec Life Systems, Inc. Cough-assist systems with humidifier bypass
DE102005063665B3 (de) * 2005-04-22 2021-01-21 Löwenstein Medical Technology S.A. Vorrichtung zur Drucksteuerung bei Beatmungsgeräten
US11191915B2 (en) 2018-05-13 2021-12-07 Ventec Life Systems, Inc. Portable medical ventilator system using portable oxygen concentrators
EP3936177A1 (fr) * 2020-07-09 2022-01-12 Albert, Alfred Respirateur
US11247015B2 (en) 2015-03-24 2022-02-15 Ventec Life Systems, Inc. Ventilator with integrated oxygen production

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20050491A1 (it) * 2005-03-24 2006-09-25 Paolo Licciulli Apparato per la somministrazione di prodotti farmaceutici in forma di aerosol
CN104870042B (zh) * 2012-12-20 2019-01-22 皇家飞利浦有限公司 用于呼吸治疗装置的内联适配器

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EP0839545A1 (fr) * 1996-10-30 1998-05-06 Taema Dispositif d'assistance respiratoire

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US4870960A (en) * 1985-10-07 1989-10-03 Litton Systems, Inc. Backup breathing gas supply for an oxygen concentrator system
EP0236850A2 (fr) * 1986-03-07 1987-09-16 Drägerwerk Aktiengesellschaft Dispositif d'alimentation de gaz pour appareil actionné pneumatiquement
FR2672221A1 (fr) * 1991-02-06 1992-08-07 Matisec Dispositif pour l'alimentation en air d'appareils respiratoires non-autonomes.
US5293864A (en) * 1991-08-01 1994-03-15 Geomet Technologies, Inc. Emergency breathing apparatus
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US5701883A (en) * 1996-09-03 1997-12-30 Respironics, Inc. Oxygen mixing in a blower-based ventilator
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Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6910484B1 (en) * 1999-05-10 2005-06-28 Maquet Critical Care Ab Constant pressure generator
US7077131B2 (en) 2000-10-19 2006-07-18 Mallinckrodt, Inc. Ventilator with dual gas supply
EP1219313A1 (fr) * 2000-12-29 2002-07-03 Instrumentarium Corporation Dispositif à projection de liquide et soupape à magnéto-matériau à mémoire de forme
DE102005031808B4 (de) 2005-04-22 2018-08-16 Löwenstein Medical Technology S.A. Vorrichtung zur Drucksteuerung bei Beatmungsgeräten
DE102005063665B3 (de) * 2005-04-22 2021-01-21 Löwenstein Medical Technology S.A. Vorrichtung zur Drucksteuerung bei Beatmungsgeräten
US9895504B2 (en) * 2011-02-08 2018-02-20 Neores Ab System and device for neonatal resuscitation and initial respiratory support
EP2842587A1 (fr) 2013-08-27 2015-03-04 Eove Appareil d'assistance respiratoire pour des personnes souffrant de troubles respiratoires et procédé de ventilation mis en oeuvre par ledit appareil
FR3009966A1 (fr) * 2013-08-27 2015-03-06 Fabien Cotteaux Appareil d'assistance respiratoire pour des personnes souffrant de troubles respiratoires et procede de ventilation mis en œuvre par ledit appareil
US10518059B2 (en) 2015-03-24 2019-12-31 Ventec Life Systems, Inc. Passive leak valve
US11185655B2 (en) 2015-03-24 2021-11-30 Ventec Life Systems, Inc. Passive leak valve
US10315002B2 (en) * 2015-03-24 2019-06-11 Ventec Life Systems, Inc. Ventilator with integrated oxygen production
US11992619B2 (en) 2015-03-24 2024-05-28 Ventec Life Systems, Inc. Ventilator with integrated cough-assist
US20160279363A1 (en) * 2015-03-24 2016-09-29 Ventec Life Systems, Inc. Ventilator with integrated oxygen production
US10576237B2 (en) 2015-03-24 2020-03-03 Ventec Life Systems, Inc. Active exhalation valve
US10758699B2 (en) 2015-03-24 2020-09-01 Ventec Life Systems, Inc. Secretion trap
US11344692B2 (en) 2015-03-24 2022-05-31 Ventec Life Systems, Inc. Respiratory therapy systems and methods
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EP1011773A4 (fr) 2002-02-20
EP1011773A1 (fr) 2000-06-28

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