WO1999063074A3 - Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes - Google Patents
Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes Download PDFInfo
- Publication number
- WO1999063074A3 WO1999063074A3 PCT/US1999/012515 US9912515W WO9963074A3 WO 1999063074 A3 WO1999063074 A3 WO 1999063074A3 US 9912515 W US9912515 W US 9912515W WO 9963074 A3 WO9963074 A3 WO 9963074A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ligand
- altering
- nucleic acid
- nucleotide composition
- binding
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 6
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000002773 nucleotide Substances 0.000 title abstract 2
- 125000003729 nucleotide group Chemical group 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 108091023040 Transcription factor Proteins 0.000 abstract 1
- 102000040945 Transcription factor Human genes 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 210000001236 prokaryotic cell Anatomy 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
Landscapes
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La présente invention concerne une méthode permettant d'améliorer le niveau d'expression relatif d'un eukaryote, d'un prokaryiote, d'un virus ou de tout autre gène d'intérêt dans des lignées cellulaires eukaryiotes ou prokaryiotes, ainsi que des procédés et produits connexes.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8794598P | 1998-06-04 | 1998-06-04 | |
| US60/087,945 | 1998-06-04 | ||
| US32324499A | 1999-06-03 | 1999-06-03 | |
| US09/323,244 | 1999-06-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1999063074A2 WO1999063074A2 (fr) | 1999-12-09 |
| WO1999063074A3 true WO1999063074A3 (fr) | 2000-04-06 |
Family
ID=26777546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1999/012515 WO1999063074A2 (fr) | 1998-06-04 | 1999-06-04 | Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO1999063074A2 (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109750039B (zh) * | 2019-01-21 | 2022-09-20 | 北京大学 | 一种植物碰触响应启动子及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995000665A1 (fr) * | 1993-06-17 | 1995-01-05 | The Research Foundation Of State University Of New York | Thermodynamique, conception et utilisation de sequences d'acides nucleiques |
| WO1998037242A1 (fr) * | 1997-02-24 | 1998-08-27 | Tm Technologies, Inc. | Procede de selection d'oligonucleotides antisens |
| WO1999032664A1 (fr) * | 1997-12-23 | 1999-07-01 | Tm Technologies, Inc. | Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands |
| WO1999042621A2 (fr) * | 1998-02-21 | 1999-08-26 | Tm Technologies, Inc. | Proprietes thermodynamiques d'acides nucleiques |
-
1999
- 1999-06-04 WO PCT/US1999/012515 patent/WO1999063074A2/fr active Application Filing
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995000665A1 (fr) * | 1993-06-17 | 1995-01-05 | The Research Foundation Of State University Of New York | Thermodynamique, conception et utilisation de sequences d'acides nucleiques |
| WO1998037242A1 (fr) * | 1997-02-24 | 1998-08-27 | Tm Technologies, Inc. | Procede de selection d'oligonucleotides antisens |
| WO1999032664A1 (fr) * | 1997-12-23 | 1999-07-01 | Tm Technologies, Inc. | Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands |
| WO1999042621A2 (fr) * | 1998-02-21 | 1999-08-26 | Tm Technologies, Inc. | Proprietes thermodynamiques d'acides nucleiques |
Non-Patent Citations (1)
| Title |
|---|
| "Non-contacted sequences flanking a ligand binding site can modulate the affinity of ligand binding: implications of such modulation in single strand to duplex reaction design", BIOPHYSICAL JOURNAL, VOL. 74,NO.2,PART 2, 22 - 26 FEBRUARY 1998, PAGE A5, XP002116814 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999063074A2 (fr) | 1999-12-09 |
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