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WO1999062545A3 - GnRH VACCINES FOR SUPPRESSING REPRODUCTIVE BEHAVIOUR IN ANIMALS - Google Patents

GnRH VACCINES FOR SUPPRESSING REPRODUCTIVE BEHAVIOUR IN ANIMALS Download PDF

Info

Publication number
WO1999062545A3
WO1999062545A3 PCT/CA1999/000493 CA9900493W WO9962545A3 WO 1999062545 A3 WO1999062545 A3 WO 1999062545A3 CA 9900493 W CA9900493 W CA 9900493W WO 9962545 A3 WO9962545 A3 WO 9962545A3
Authority
WO
WIPO (PCT)
Prior art keywords
gnrh
animals
methods
suppressing
gnrh vaccines
Prior art date
Application number
PCT/CA1999/000493
Other languages
French (fr)
Other versions
WO1999062545A2 (en
Inventor
Sarah C Robbins
Original Assignee
Biostar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biostar Inc filed Critical Biostar Inc
Priority to NZ509137A priority Critical patent/NZ509137A/en
Priority to EP99923336A priority patent/EP1098661A2/en
Priority to BR9910905-0A priority patent/BR9910905A/en
Priority to AU40261/99A priority patent/AU771556B2/en
Priority to JP2000551800A priority patent/JP2002516875A/en
Publication of WO1999062545A2 publication Critical patent/WO1999062545A2/en
Publication of WO1999062545A3 publication Critical patent/WO1999062545A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Methods for achieving suppression of reproductive behavior and/or fertility in a vertebrate subject are disclosed. The methods us e compositions which include GnRH immunogens, GnRH ananlogs such as GnRH agonists and antagonists, and GnRH antibodies. The methods are useful for the prolonged suppression of testicular function in males and ovarian function in females.
PCT/CA1999/000493 1998-06-04 1999-05-28 GnRH VACCINES FOR SUPPRESSING REPRODUCTIVE BEHAVIOUR IN ANIMALS WO1999062545A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
NZ509137A NZ509137A (en) 1998-06-04 1999-05-28 Methods for reducing GnRH levels in prepubertal vertebrates as an alternative to surgical sterilisation
EP99923336A EP1098661A2 (en) 1998-06-04 1999-05-28 Gnrh vaccines for suppressing reproductive behavior in animals
BR9910905-0A BR9910905A (en) 1998-06-04 1999-05-28 Gnrh vaccines to suppress reproductive behavior in animals.
AU40261/99A AU771556B2 (en) 1998-06-04 1999-05-28 Methods for suppressing reproductive behavior in animals
JP2000551800A JP2002516875A (en) 1998-06-04 1999-05-28 How to control animal reproductive behavior

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60/088,024 1995-10-27
US8802498P 1998-06-04 1998-06-04
US30668999A 1999-05-06 1999-05-06
US09/306,689 1999-05-06

Publications (2)

Publication Number Publication Date
WO1999062545A2 WO1999062545A2 (en) 1999-12-09
WO1999062545A3 true WO1999062545A3 (en) 2001-03-15

Family

ID=26777682

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA1999/000493 WO1999062545A2 (en) 1998-06-04 1999-05-28 GnRH VACCINES FOR SUPPRESSING REPRODUCTIVE BEHAVIOUR IN ANIMALS

Country Status (6)

Country Link
EP (1) EP1098661A2 (en)
JP (1) JP2002516875A (en)
AU (1) AU771556B2 (en)
BR (1) BR9910905A (en)
NZ (1) NZ509137A (en)
WO (1) WO1999062545A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8734811B2 (en) * 2009-04-06 2014-05-27 University Of Saskatchewan Methods and compositions for treating and preventing Shiga toxin-producing Escherichia coli infection

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556555A (en) * 1985-01-25 1985-12-03 North Carolina State University Process for the immunological neutering of animals
WO1988005308A1 (en) * 1987-01-14 1988-07-28 Commonwealth Scientific And Industrial Research Or Anti reproductive hormone
WO1990011298A1 (en) * 1989-03-23 1990-10-04 Stichting Centraal Diergeneeskundig Instituut A peptide, immunogenic composition and vaccine or medicinal preparation; a method of immunising a mammal against lhrh, and a method of improving the meat quality of pigs
WO1991004052A1 (en) * 1989-09-22 1991-04-04 Peptide Technology Ltd. Vaccines
WO1998006848A1 (en) * 1996-08-09 1998-02-19 University Of Saskatchewan GnRH-LEUKOTOXIN CHIMERAS

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556555A (en) * 1985-01-25 1985-12-03 North Carolina State University Process for the immunological neutering of animals
WO1988005308A1 (en) * 1987-01-14 1988-07-28 Commonwealth Scientific And Industrial Research Or Anti reproductive hormone
WO1990011298A1 (en) * 1989-03-23 1990-10-04 Stichting Centraal Diergeneeskundig Instituut A peptide, immunogenic composition and vaccine or medicinal preparation; a method of immunising a mammal against lhrh, and a method of improving the meat quality of pigs
WO1991004052A1 (en) * 1989-09-22 1991-04-04 Peptide Technology Ltd. Vaccines
WO1998006848A1 (en) * 1996-08-09 1998-02-19 University Of Saskatchewan GnRH-LEUKOTOXIN CHIMERAS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BROWN B.W. ET AL: "Immunization of sheep against GnRH early in life: effects on reproductive function and hormones in ewes", JOURNAL OF REPRODUCTION AND FERTILITY, vol. 103, no. 1, 1995, pages 131 - 135, XP002120455 *
BROWN B.W. ET AL: "Immunization of sheep against GnRH early in life: effects on reproductive function and hormones in rams", JOURNAL OF REPRODUCTION AND FERTILITY, vol. 101, no. 1, 1994, pages 15 - 21, XP002120454 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; JAGO J G ET AL: "The effect of prepubertal immunization against gonadotropin - releasing hormone on the development of sexual and social behavior of bulls.", XP002120456, retrieved from STN Database accession no. 97472903 *
JOURNAL OF ANIMAL SCIENCE, (1997 OCT) 75 (10) 2609-19. *

Also Published As

Publication number Publication date
NZ509137A (en) 2004-01-30
JP2002516875A (en) 2002-06-11
WO1999062545A2 (en) 1999-12-09
AU4026199A (en) 1999-12-20
EP1098661A2 (en) 2001-05-16
BR9910905A (en) 2001-02-13
AU771556B2 (en) 2004-03-25

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