+

WO1999061640A3 - Aav derived vector - Google Patents

Aav derived vector Download PDF

Info

Publication number
WO1999061640A3
WO1999061640A3 PCT/GB1999/001633 GB9901633W WO9961640A3 WO 1999061640 A3 WO1999061640 A3 WO 1999061640A3 GB 9901633 W GB9901633 W GB 9901633W WO 9961640 A3 WO9961640 A3 WO 9961640A3
Authority
WO
WIPO (PCT)
Prior art keywords
derived vector
aav derived
aav
vector
encapsidating
Prior art date
Application number
PCT/GB1999/001633
Other languages
French (fr)
Other versions
WO1999061640A2 (en
Inventor
Robert James Anderson
Hugh Grant Prentice
Ian Duncan Macdonald
Original Assignee
Univ London
Robert James Anderson
Hugh Grant Prentice
Ian Duncan Macdonald
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ London, Robert James Anderson, Hugh Grant Prentice, Ian Duncan Macdonald filed Critical Univ London
Publication of WO1999061640A2 publication Critical patent/WO1999061640A2/en
Publication of WO1999061640A3 publication Critical patent/WO1999061640A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

An adeno-associated viral vector containing a transgene and encapsidating a protein with adenovirus E4 ORF6 activity.
PCT/GB1999/001633 1998-05-22 1999-05-21 Aav derived vector WO1999061640A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9811171.9A GB9811171D0 (en) 1998-05-22 1998-05-22 Viral vector
GB9811171.9 1998-05-22

Publications (2)

Publication Number Publication Date
WO1999061640A2 WO1999061640A2 (en) 1999-12-02
WO1999061640A3 true WO1999061640A3 (en) 2000-01-27

Family

ID=10832634

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/001633 WO1999061640A2 (en) 1998-05-22 1999-05-21 Aav derived vector

Country Status (2)

Country Link
GB (1) GB9811171D0 (en)
WO (1) WO1999061640A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468181B2 (en) 2002-04-25 2008-12-23 Crucell Holland B.V. Means and methods for the production of adenovirus vectors

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10056210A1 (en) * 2000-11-13 2002-05-29 Arimedes Biotechnology Gmbh Viral expression system
US8912142B2 (en) 2009-04-01 2014-12-16 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Method of regulating proliferation and differentiation of keratinocyes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996000587A1 (en) * 1994-06-30 1996-01-11 University Of Pittsburgh Aav capsid vehicles for molecular transfer
WO1996022378A1 (en) * 1995-01-20 1996-07-25 Rhone-Poulenc Rorer S.A. Cells for the production of recombinant adenoviruses
WO1996039530A2 (en) * 1995-06-05 1996-12-12 The Trustees Of The University Of Pennsylvania Recombinant adenovirus and adeno-associated virus, cell lines, and methods of production and use thereof
WO1997009441A2 (en) * 1995-09-08 1997-03-13 Genzyme Corporation Improved aav vectors for gene therapy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996000587A1 (en) * 1994-06-30 1996-01-11 University Of Pittsburgh Aav capsid vehicles for molecular transfer
WO1996022378A1 (en) * 1995-01-20 1996-07-25 Rhone-Poulenc Rorer S.A. Cells for the production of recombinant adenoviruses
WO1996039530A2 (en) * 1995-06-05 1996-12-12 The Trustees Of The University Of Pennsylvania Recombinant adenovirus and adeno-associated virus, cell lines, and methods of production and use thereof
WO1997009441A2 (en) * 1995-09-08 1997-03-13 Genzyme Corporation Improved aav vectors for gene therapy

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FERRARI F. K. ET AL.: "SECOND-STRAND SYNTHESIS IS A RATE-LIMITING STEP FOR EFFICIENT TRANSDUCTION BY RECOMBINANT ADENO-ASSOCIATED VIRUS VECTORS", JOURNAL OF VIROLOGY,US,THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 70, no. 5, pages 3227-3234, XP000570467, ISSN: 0022-538X *
FISHER K. J. ET AL.: "TRANSDUCTION WITH RECOMBINANT ADENO-ASSOCIATED VIRUS FOR GENE THERAPY IS LIMITED BY LEADING-STRAND SYNTHESIS", JOURNAL OF VIROLOGY,US,THE AMERICAN SOCIETY FOR MICROBIOLOGY, vol. 70, no. 1, pages 520-532, XP000570468, ISSN: 0022-538X *
LEPPARD K. N.: "E4 gene function in adenovirus, adenovirus vector and adenovirus infections", JOURNAL OF GENERAL VIROLOGY,GB,SOCIETY FOR GENERAL MICROBIOLOGY, READING, vol. 78, pages 2131-2138, XP002086863, ISSN: 0022-1317 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468181B2 (en) 2002-04-25 2008-12-23 Crucell Holland B.V. Means and methods for the production of adenovirus vectors

Also Published As

Publication number Publication date
GB9811171D0 (en) 1998-07-22
WO1999061640A2 (en) 1999-12-02

Similar Documents

Publication Publication Date Title
AU5588298A (en) Adeno-associated viral vector-mediated delivery of dna to cells of the liver
NL1008164A1 (en) More spacious.
NZ316806A (en) Vector comprising one or more adeno-associated viral itrs
AU5583299A (en) Multiple mode audio cassette emulator
AU3309997A (en) Recombinant adeno-associated viral vectors
AU2001234981A1 (en) Adenoviral capsid containing chimeric protein ix
AU1340000A (en) Novel adenoviral vector and methods for making and using the same
AU5734998A (en) Embryonic stem cell serum replacement
AU3589197A (en) Recombinant canine adenovirus (cav) containing exogenous dna
ZA200003283B (en) Topical compositions containing whey proteins.
FI970579L (en) Adenovirus containing the gene encoding glutathione peroxidase
AU9388398A (en) Digital signal processor with variable width instructions
AU1581099A (en) An instruction decoder
AU2001238079A1 (en) Antibody gene therapy with adeno-associated viral vectors
FI965231L (en) Adenovirus containing the gene encoding superoxide dismutase
AU4298796A (en) An enzyme preparation with cellulytic activity
AU1941499A (en) Processor pipeline with interstage queue of micro-ops for selective back-end replay
AU5846598A (en) Promoter of the CDC25B gene, its preparation and use
EP0665033A3 (en) Unitary molded single blade ski-sled.
AU6483499A (en) Genetic variation associated with aplastic anemia, and diagnosis and therapy based thereon
AU2344100A (en) Viral vectors with late transgene expression
WO1999061640A3 (en) Aav derived vector
AU2660400A (en) Rantes-derived peptides with anti-hiv activity
AU1266499A (en) Igg-binding protein from (staphylococcus) and nucleotide sequence encoding this protein
AU3063699A (en) Isolated mammalian membrane protein genes and related reagents

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载