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WO1999060117A3 - Polypeptide prax-1 - Google Patents

Polypeptide prax-1 Download PDF

Info

Publication number
WO1999060117A3
WO1999060117A3 PCT/FR1999/001070 FR9901070W WO9960117A3 WO 1999060117 A3 WO1999060117 A3 WO 1999060117A3 FR 9901070 W FR9901070 W FR 9901070W WO 9960117 A3 WO9960117 A3 WO 9960117A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
seq
sequence
sequence seq
prax
Prior art date
Application number
PCT/FR1999/001070
Other languages
English (en)
Other versions
WO1999060117A2 (fr
Inventor
Pierre Casellas
Sylvaine Galiegue
Omar Jbilo
Fur Gerard Le
Original Assignee
Sanofi Synthelabo
Pierre Casellas
Sylvaine Galiegue
Omar Jbilo
Fur Gerard Le
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo, Pierre Casellas, Sylvaine Galiegue, Omar Jbilo, Fur Gerard Le filed Critical Sanofi Synthelabo
Priority to AU35285/99A priority Critical patent/AU3528599A/en
Publication of WO1999060117A2 publication Critical patent/WO1999060117A2/fr
Publication of WO1999060117A3 publication Critical patent/WO1999060117A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Cette invention concerne un polypeptide purifié, comprenant une séquence d'acides aminés choisie parmi: a) la séquence SEQ ID n°2; b) une séquence biologiquement active dérivée de SEQ ID n°2, et c) un fragment de la séquence SEQ ID n°2 ayant une activité biologique de même nature que celle du polypeptide de séquence SEQ ID n°2, ou immunologiquement apparenté au polypeptide de séquence SEQ ID n°2.
PCT/FR1999/001070 1998-05-15 1999-05-06 Polypeptide prax-1 WO1999060117A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35285/99A AU3528599A (en) 1998-05-15 1999-05-06 Prax-1 polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9806190A FR2778665B1 (fr) 1998-05-15 1998-05-15 Polypeptide prax-1
FR98/06190 1998-05-15

Publications (2)

Publication Number Publication Date
WO1999060117A2 WO1999060117A2 (fr) 1999-11-25
WO1999060117A3 true WO1999060117A3 (fr) 2000-01-20

Family

ID=9526420

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1999/001070 WO1999060117A2 (fr) 1998-05-15 1999-05-06 Polypeptide prax-1

Country Status (3)

Country Link
AU (1) AU3528599A (fr)
FR (1) FR2778665B1 (fr)
WO (1) WO1999060117A2 (fr)

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
B. BIREN ET AL.: "Homo sapiens chromosome 17, clone hRPC.1171_I_10, complete sequence", EMBL SEQUENCE DATABASE, 15 May 1998 (1998-05-15), Cambridge, UK, XP002090577 *
D. LIN ET AL.: "The human peripheral benzodiazepine receptor gene: cloning and characterization of alternative splicing in normal tissues and in a patient with congenital lipoid adrenal hyperplasia", GENOMICS, vol. 18, no. 3, December 1993 (1993-12-01), ACADEMIC PRESS INC., NY, US, pages 643 - 650, XP002090580 *
GAVISH ET AL: "Biochemical, Physiological, and Pathological Aspects of the Peripheral Benzodiazepine Receptor", JOURNAL OF NEUROCHEMISTRY, vol. 5, no. 58, 1992, pages 1589 1589, XP002076143 *
J. NIE ET AL.: "Interacxtion of Oct-1 and automodification domain of poly(ADP-ribose) synthetase", FEBS LETTERS, vol. 424, no. 1-2, 6 March 1998 (1998-03-06), ELSEVIER, AMSTERDAM, NL, pages 27 - 32, XP002090583 *
J. RIOND ET AL.: "Molecular cloning and chromosomal localization of a human peripheral-type benzodiazepine receptor", EUR. J. BIOCHEM., vol. 195, no. 2, 30 January 1991 (1991-01-30), SPRINGER, BERLIN, D, pages 305 - 311, XP002090581 *
K.-ICHI ISHIKAWA ET AL.: "Prediction of the coding sequences of unidentified human genes. X. The complete sequence of 100 new cDNA clones from brain which can code for large proteins in vitro", DNA RESEARCH, vol. 5, 30 June 1998 (1998-06-30), KAZUSA DNA RES. UNIV.ACAD.PRESS,INC.,TOKYO,JP, pages 169 - 176, XP002090578 *
O. OHARA ET AL.: "Homo sapiens mRNA for KIAA0612 protein, partial cds.,", EMBL SEQUENCE DATABASE, 15 July 1998 (1998-07-15), Cambridge, UK *
PAPADOPOULOS V ET AL: "Peripheral benzodiazepine receptor in cholesterol transport and steroidogenesis", STEROIDS: STRUCTURE, FUNCTION, AND REGULATION, vol. 62, no. 1, January 1997 (1997-01-01), pages 21-28, XP004054224 *
R. FARGES ET AL.: "Molecular basis for the different binding properties of benzodiazepines to human and bovine peripheral-type benzodiazepine receptors", FEBS LETTERS, vol. 335, no. 3, December 1993 (1993-12-01), ELSEVIER, AMSTERDAM, NL, pages 305 - 308, XP002090582 *
S. GALIÈGUE ET AL.: "Cloning and characterization of rax-1", J. BIOL. CHEM., vol. 274, no. 5, 29 January 1999 (1999-01-29), AM. SOC. BIOCHEM. MOL.BIOL.,INC.,BALTIMORE,US, pages 2938 - 2952, XP002122735 *
S. GALIEGUE ET AL.: "Homo sapiens peripheral benzodiazepine receptor interacting protein mRNA, complete cds.;", EMBL SEQUENCE DATABASE, 6 January 1999 (1999-01-06), Cambridge, UK, XP002090579 *

Also Published As

Publication number Publication date
WO1999060117A2 (fr) 1999-11-25
FR2778665A1 (fr) 1999-11-19
AU3528599A (en) 1999-12-06
FR2778665B1 (fr) 2000-06-30

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