WO1999056712A1 - Procede pour la preparation d'un produit pharmaceutique et/ou cosmetique stimulant le metabolisme cutane et capillaire et hydratant, et produit ainsi obtenu - Google Patents
Procede pour la preparation d'un produit pharmaceutique et/ou cosmetique stimulant le metabolisme cutane et capillaire et hydratant, et produit ainsi obtenu Download PDFInfo
- Publication number
- WO1999056712A1 WO1999056712A1 PCT/ES1999/000103 ES9900103W WO9956712A1 WO 1999056712 A1 WO1999056712 A1 WO 1999056712A1 ES 9900103 W ES9900103 W ES 9900103W WO 9956712 A1 WO9956712 A1 WO 9956712A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pharmaceutical
- water
- cosmetic product
- seed extract
- perfume
- Prior art date
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- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229940031661 dimethicone 350 Drugs 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 229940074047 glyceryl cocoate Drugs 0.000 description 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000002803 maceration Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000036284 oxygen consumption Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000003169 placental effect Effects 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 210000001626 skin fibroblast Anatomy 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000012905 visible particle Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
Definitions
- the present invention relates to a process for the preparation of a pharmaceutical and / or cosmetic product of stimulating action of the cutaneous and capillary and moisturizing metabolism, comprising the steps of obtaining an extract of the seeds of at least one plant variety , intended to be used as an active ingredient, and to mix the extract with other additive ingredients and / or excipients.
- the invention also relates to the pharmaceutical and / or cosmetic product of stimulating action of the cutaneous and capillary and moisturizing metabolism, obtained according to said method.
- fibrous proteins mainly collagen and elastin
- glycosaminoglycans that constitute the structural elements of this tissue par excellence.
- the synthesis, that is, the manufacture and development, of these fibrous proteins takes place in cells known as fibroblasts, thanks to the presence of oxygen and other necessary nutrients, such as, for example, adenosine triphosphate, nucleotide best known in the art by ATP.
- fibroblasts cells known as fibroblasts, thanks to the presence of oxygen and other necessary nutrients, such as, for example, adenosine triphosphate, nucleotide best known in the art by ATP.
- These dermatological products based on placental extracts base their reparative action on a set of molecules with biological activity, capable of penetrating the innermost layers of the skin, providing the energy necessary to increase the synthesis of the said fibrous proteins constituting the skin tissue, producing the beneficial effect on human skin of preventing and delaying the appearance of signs of skin aging.
- seed germ extracts are used, prior to germination, in order to stimulate the metabolism of the skin.
- seed extracts after germination is also known, either as antioxidant agents or as a means of preventing the occurrence of so-called free radicals, such as the procedure described in Japanese patent JP-93/332374.
- the purpose of the present invention is to provide a novel process for the preparation of a pharmaceutical and / or cosmetic preparation, as well as the product obtained from such a procedure, that fills the vacuum existing in the art.
- a first object of the present invention is a process for the preparation of a pharmaceutical and / or cosmetic product, of novel concept, which in essence is characterized in that said step of obtaining the extract is carried out after germination of the seeds grown biologically in water, in the absence of pesticides and additives, for a predetermined period of time.
- the germination of the seeds is hydroponically stimulated in an open container culture, at a temperature between 18 and 20 ° C, an ambient humidity between 70 and 75%, under artificial light , ultraviolet light and ultrasound.
- said predetermined period of time is between five and fifteen days.
- said step of obtaining the seed extract is applied to seeds of plants selected from the group of plant varieties consisting of soy, wheat, oats, rice, millet, corn, barley, rye, - 5 - Alfalfa, radish, peanut, pea and beans.
- a second object of the present invention is a pharmaceutical and / or cosmetic product, obtained according to the above procedure, which is essentially characterized in that it comprises a minimum proportion of 0.01% by weight of the germinated seed extract.
- the product contains approximate weight proportions of: germinated seed extract, 2.00; water, 24.70; 28% sodium lauryl ether sulfate, 55.00; preservative, 0.05; PEG-4 Rapessedamide, 0.30; 30% propyl betaine cocamido, 16.00; PEG-7 glyceryl cocoate, 1.00; perfume, 0.50; 99% triethanolamine, 0.06; CI 16035, 0.04; CI 19140, 0.20; and Sodium Chloride, 0.15.
- the product contains approximate proportions by weight of: germinated seed extract, 2.00; water, 55.87; Guar hydroxypropyl chloride hydroxypropyltrimony, 0.20; citric acid, 0.03; 40% triethanolamine lauryl sulfate, 30.00; preservative, 0.50; 30% propyl betaine cocamido, 8.00; dimethicone copolyol, 0.50; PEG-7 glyceryl cocoate, 0.50; 50% decyl polyglucose, 2.00; and perfume, 0.40. - 6 -
- the product contains approximate proportions by weight of: germinated seed extract, 2.00; water, 57.10; preservative, 0.50; 30% propyl betaine cocamido, 4.00; 30% cocamidopropylamine oxide, 5.00; 30% sodium lauryl ether sulfosuccinate, 17.00; cocamido monoethanolamide, 1.30; Sodium C14-16 Olefin sulfonate 37%, 12.00; lactic acid, 0.10; sodium chloride, 0.50; and perfume, 0.50.
- the product contains approximate weight proportions of: germinated seed extract, 1.00; Guar hydroxypropyl chloride hydroxypropyltrimony 0.05; Polyquaternium-10, 0.25; water, 55.20; lactic acid, 0.10; 28% sodium lauryl ether sulfate, 28.00; Quaternium-15, 0.05; methylparaben, 0.15; pantothenol, 0.30; Polyquaternium- 39, 1.50; 30% propyl betaine cocamido, 5.00; 25% stearamine oxide, 1.50; 50% decyl polyglucose, 5.00; 50% propylene glycol and / or 50% propylene glycol oleate, 0.80; perfume, 0.40; lactic acid, 0.60; and sodium chloride, 0.10.
- the product contains approximate proportions by weight of: germinated seed extract,
- the product contains approximate weight proportions of: germinated seed extract, 2.00; water, 72.35; Acrylates / C10-30 Alkyl Acrylates Crosspolymer, 0.30; glycerin, 2.00 Aloe barbadensis, 8.00; 99% triethanolamine, 0.15 denatured alcohol, 10.00; menthol, 0.20; BHT, 0.05 preservative, 0.50; PPG-15 stearyl ether, 3.00 perfume, 1.25; bisabolol, 0.10; and EDTA disodium, 0.10.
- the product contains approximate weight proportions of: germinated seed extract, 2.00; 50% PEG-100 stearate and / or 50% glyceryl sterate, 6.00; Vaseline, 3.00; cetyl alcohol, 2.50; liquid petrolatum oil, 9.00 octyl methoxycinnamate, 9.00; benzophenone-3, 3.50 wheat germ oil ("triticum vulgare"), 1.50 BHT, 0.10; water, 55.40; propylene glycol, 2.00; preserve tea, 0.70; perfume, 0.30; and titanium dioxide, 3.00.
- the product contains approximate proportions by weight of: germinated seed extract, 1.00; glyceryl stearate and / or Ceteth-20, 3.00; stearyl alcohol, Steareth 7 and / or Steareth 10, 5.00; cetyl alcohol, 1.00; caprylic / capric triglyceride, 4.00; BHT, 0.10; wheat germ oil ("triticum vulgaris"), 3.00; benzophenone-3, 1.00; liquid petrolatum oil, 7.00; octyl methoxycinnamate, 4.00; water, 72.35; perfume, 0.35; and preservative, 0.70.
- the product contains approximate proportions by weight of: germinated seed extract, 2.00; water, 79.30; rose water ("Rosa Canina”), 15.00; preservative, 0.50; propylene glycol, 2.50; perfume, 0.10; hydrogenated castor oil PEG-40, 0.60; and a sufficient amount of CI 16035.
- the product contains approximate weight proportions of: germinated seed extract, 2 , 00; Steareth-2, 2.40; Steareth-21, 1.60; PEG-15 stearyl ether, 4.00; liquid petrolatum oil, 3.00; preservative, 0.60; cetyl alcohol, 3.00; benzophenone-3, 0.50; wheat germ oil ("triticum vulgare"), 1.00; BHT, 0.10; alba wax, 1.00; propylene glycol, 2.50; water, 75.90; dimethicone copolyol, 2.00; and perfume, 0.40.
- the product contains approximate weight proportions of: germinated seed extract, 2.00; propylene glycol, 2.00; xanthan gum, 0.20; water, 91.70; preservative, 0.60; polyacrylamide, C13-14 isoparaffin and / or lauryl ether-7, 1.00; octyl cocoate, 2.00; perfume, 0.15; lactic acid, 0.10; CI 42090, 0.02; and CI 19140, 0.03.
- the product contains approximate weight proportions of: germinated seed extract, 2.00; cetyl dimethicone copolyol, 2.00; polyglyceryl-3 oleate, 0.75; cetyl dimethicone, 2.00; octyl palmitate, 3.00; hydrogenated castor oil, 0.40; beeswax, 0.80; decyl oleate, 1.00; 350 cst dimethicone, 0.25; octyl stearate, 3.00; cyclomethicone, 15.00; brown iron oxides, 0.30; red, yellow and / or black titanium dioxide, 2.10; water, 64.90; sodium chloride, 0.50; and propylene glycol, 2.00.
- the extracts according to the present invention are made from seeds of plants selected from the group of plant varieties consisting of soy, wheat, oats, rice, millet, corn, barley, rye, alfalfa, radish, peanut, pea and beans.
- the procedure consists in itself of a stage of cultivation and germination of seeds, a stage of obtaining an extract of the germinated seeds (germinated) and a stage of addition of components to the germinated.
- the sprouts used are preferably obtained by the so-called hydroponic system.
- the hydroponic system consists, in a generic way, in the practice of plant crops in the absence of soil and in an artificial environment.
- the hydroponic germination system was applied to two biological crops: one of wheat seeds, and another formed by a mixture of wheat, soy, alfalfa and radish seeds. Both cultures were maintained with only water and in the absence of pesticides and other chemical agents, at a temperature between 18 and 20 ° C, with a - 11 - ambient humidity between 70 and 75% and with artificial light. In both crops, the seeds underwent a germination process from the first day in the same container without the need to handle the product once the process was finished. In order to maintain the constancy of air quality, during the germination process it was applied to ultrasound and ultraviolet light cultures.
- the hydroponic method is advantageous with respect to the other possible cited as it allows the growth of sprouts with the formation of a microenvironment, not caked and with longitudinal growth, as well as with a lower concentration of water present, which favors its conservation.
- the fact that sprouts are deposited in open tanks facilitates metabolic processes. In this case, the synthesis of chlorophyll has been verified by direct light.
- hydroponic culture system is the most suitable for measuring the optimum levels of vital components in the germinated seed that must be active ingredients in the future extract, that is, monosaccharides, oligosaccharides, peptides, amino acids, minerals and vitamins.
- the germination process was interrupted when the measured concentrations of these elements had a maximum. Germination could have been just ⁇ interrupted when the rate of increase of such - 12 - concentrations begin to decrease. Preferably, germination stops after five to fifteen days of cultivation. In the particular tests carried out, germination was interrupted on the seventh day of its beginning.
- the seeds of both crops were subjected to rapid freezing at temperatures below -20 ° C, and were kept frozen until they were extracted.
- the extraction of the germinated seeds began by grinding and disintegrating them in their frozen form. Then the extraction was carried out by maceration using a hydroalcoholic extraction solvent containing 20% by weight of 98% ethyl alcohol, maintaining a plant-solvent extraction ratio of 1: 2, at a maximum temperature of 80 ° C for 15 minutes. The extraction process lasted for 24 hours.
- the product obtained after filtration was a fully transparent, crisp, active substance with - 13 - absence of visible particles.
- the hydration of the skin surface was measured, using two cosmetic formulations, one of which contained 3% of the active substance, while the other was a formula- - 14 - control or placebo tion.
- CM 825 Courage & Khazaka the capacitance values of the skin surface were recorded. This method is based on the dielectric constant of water, usually 81 units of capacitance, while the rest of substances have values lower than 7 units, so that the measured capacitance changes are a measurable function of water levels, and therefore of skin hydration.
- the experiment was designed as an experimental, randomized and "double blind" study. The results obtained show that the use of cosmetic and pharmaceutical formulations containing germinated seed extracts increase skin hydration.
- the skin elasticity of the skin was analyzed by measuring its degree of recovery after applying a certain suction pressure performed using a device known in the art as "Cutometer” (model SEM 474 of Courage & Khazaka).
- the test was performed by applying a cosmetic formulation of the extract according to the invention and a placebo formulation on the cheek of 6 volunteers, applying low pressure (300 mbar). The measurement was made three times to each volunteer before starting the treatment and another three after the end of it.
- the values of the parameters R9 (experimental elasticity value), R0 (maximum extension value) and Rl (recovery capacity) were obtained, which are shown in Table I below:
- Germinated seed extract 2.00
- Germinated seed extract 2.00
- Example 4 conditioning shampoo. - Guar hydroxypropyl chloride hydroxypropyltrimony 0.05 Polyquaternium- 10 0.25
- Example 5 hair tonic.
- Example 7 high protection sunscreen.
- Germinated seed extract 2.00
- Example 8 medium protection solar milk .-
- Glyceryl stearate Ceteth-20 3.00 - twenty -
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- Health & Medical Sciences (AREA)
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- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
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- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
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Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU33337/99A AU3333799A (en) | 1998-05-05 | 1999-04-20 | Process for the preparation of a pharmaceutical and/or cosmetic product stimulating the cutaneous and capillar and hydrating metabolism, and product obtained bysuch process |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ESP9800939 | 1998-05-05 | ||
ES009800939A ES2136580B1 (es) | 1998-05-05 | 1998-05-05 | Procedimiento para la preparacion de un producto farmaceutico y/o cosmetico estimulante del metabolismo cutaneo y capilar e hidratante, y producto obtenido mediante dicho procedimiento. |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999056712A1 true WO1999056712A1 (fr) | 1999-11-11 |
Family
ID=8303677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/ES1999/000103 WO1999056712A1 (fr) | 1998-05-05 | 1999-04-20 | Procede pour la preparation d'un produit pharmaceutique et/ou cosmetique stimulant le metabolisme cutane et capillaire et hydratant, et produit ainsi obtenu |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU3333799A (fr) |
ES (1) | ES2136580B1 (fr) |
WO (1) | WO1999056712A1 (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1262167A1 (fr) * | 2001-06-01 | 2002-12-04 | Cognis France S.A. | Préparations cosmétiques contenant un extrait de plantes germantes |
GB2414669A (en) * | 2004-06-04 | 2005-12-07 | Coletica | Compositions for topical use to increase the concentration of active TGFbeta-1 |
US7591272B2 (en) | 2005-08-17 | 2009-09-22 | Colgate-Palmolive Co. | Acidic cleaning composition containing a hydrophilizing polymer, a surfactant, and an acid |
FR2958847A1 (fr) * | 2010-04-15 | 2011-10-21 | Isp Investments Inc | Utilisation d'un hydrolysat peptidique de pois en tant qu'agent actif hydratant |
CN103027876A (zh) * | 2012-12-14 | 2013-04-10 | 吴江市德佐日用化学品有限公司 | 一种护肤洗手液 |
EP1536753B1 (fr) | 2002-09-13 | 2016-02-17 | BASF Beauty Care Solutions S.A.S. | Procede de protection et de modulation des jonctions derme-epiderme |
CN106377460A (zh) * | 2016-10-31 | 2017-02-08 | 贞丰县精品农业综合开发有限公司 | 一种玫瑰精华原液及其制备方法 |
WO2019072982A1 (fr) * | 2017-10-11 | 2019-04-18 | Alaena Cosmetiques | Principe actif cosmetique a base d'extraits de graines germees |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2941376B1 (fr) * | 2009-01-28 | 2012-10-12 | Limousine D Applic Biolog Ditesilab Soc Ind | Utilisation cosmetique anti-stress et/ou anti-age d'un principe actif issu de panicum miliaceum, principe actif, procede d'obtention et compositions |
ES2542163B1 (es) * | 2014-01-30 | 2016-06-06 | Consejo Superior De Investigaciones Científicas (Csic) | Procedimiento de obtención de granos de arroz integral germinado yproductos derivados de los mismos que comprenden compuestosbiológicamente activos |
CN109526594B (zh) * | 2017-07-26 | 2021-07-30 | 北京神飞航天应用技术研究院 | 一种航天阳台蔬菜的栽培方法 |
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WO1989004599A1 (fr) * | 1987-11-24 | 1989-06-01 | Bogdanyne Forgacs Olga | Preparation et utilisation de plantes de valeur biologique accrue |
ES2020652A6 (es) * | 1990-07-17 | 1991-08-16 | Andromaco Lab | Procedimiento de obtencion de un producto de naturaleza oligosacaridica con actividad estimuladora de la reparacion tisular. |
FR2705031A1 (fr) * | 1993-05-10 | 1994-11-18 | Sederma Sa | Nouvelles compositions cosmétiques et dermopharmaceutiques contenant des protéines végétales amphipathiques (oléosines) extraites des globules gras des graines de colza, de soja, de lin. |
WO1995011663A1 (fr) * | 1993-10-29 | 1995-05-04 | Nurture, Inc. | Substances et formulations proteiniques de protection contre la formation de cellules erythemateuses |
-
1998
- 1998-05-05 ES ES009800939A patent/ES2136580B1/es not_active Expired - Fee Related
-
1999
- 1999-04-20 AU AU33337/99A patent/AU3333799A/en not_active Abandoned
- 1999-04-20 WO PCT/ES1999/000103 patent/WO1999056712A1/fr active Application Filing
Patent Citations (4)
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WO1989004599A1 (fr) * | 1987-11-24 | 1989-06-01 | Bogdanyne Forgacs Olga | Preparation et utilisation de plantes de valeur biologique accrue |
ES2020652A6 (es) * | 1990-07-17 | 1991-08-16 | Andromaco Lab | Procedimiento de obtencion de un producto de naturaleza oligosacaridica con actividad estimuladora de la reparacion tisular. |
FR2705031A1 (fr) * | 1993-05-10 | 1994-11-18 | Sederma Sa | Nouvelles compositions cosmétiques et dermopharmaceutiques contenant des protéines végétales amphipathiques (oléosines) extraites des globules gras des graines de colza, de soja, de lin. |
WO1995011663A1 (fr) * | 1993-10-29 | 1995-05-04 | Nurture, Inc. | Substances et formulations proteiniques de protection contre la formation de cellules erythemateuses |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1262167A1 (fr) * | 2001-06-01 | 2002-12-04 | Cognis France S.A. | Préparations cosmétiques contenant un extrait de plantes germantes |
EP1536753B1 (fr) | 2002-09-13 | 2016-02-17 | BASF Beauty Care Solutions S.A.S. | Procede de protection et de modulation des jonctions derme-epiderme |
GB2414669A (en) * | 2004-06-04 | 2005-12-07 | Coletica | Compositions for topical use to increase the concentration of active TGFbeta-1 |
GB2414669B (en) * | 2004-06-04 | 2007-04-11 | Coletica | Extracts from plants and fish which induce the conversion of inactive TGFb-latent into its active form |
US7591272B2 (en) | 2005-08-17 | 2009-09-22 | Colgate-Palmolive Co. | Acidic cleaning composition containing a hydrophilizing polymer, a surfactant, and an acid |
FR2958847A1 (fr) * | 2010-04-15 | 2011-10-21 | Isp Investments Inc | Utilisation d'un hydrolysat peptidique de pois en tant qu'agent actif hydratant |
CN103027876A (zh) * | 2012-12-14 | 2013-04-10 | 吴江市德佐日用化学品有限公司 | 一种护肤洗手液 |
CN106377460A (zh) * | 2016-10-31 | 2017-02-08 | 贞丰县精品农业综合开发有限公司 | 一种玫瑰精华原液及其制备方法 |
WO2019072982A1 (fr) * | 2017-10-11 | 2019-04-18 | Alaena Cosmetiques | Principe actif cosmetique a base d'extraits de graines germees |
Also Published As
Publication number | Publication date |
---|---|
ES2136580A1 (es) | 1999-11-16 |
AU3333799A (en) | 1999-11-23 |
ES2136580B1 (es) | 2000-07-01 |
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