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WO1999054713A3 - Device and method for detecting a shift in a surface plasmon resonance - Google Patents

Device and method for detecting a shift in a surface plasmon resonance Download PDF

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Publication number
WO1999054713A3
WO1999054713A3 PCT/EP1999/002661 EP9902661W WO9954713A3 WO 1999054713 A3 WO1999054713 A3 WO 1999054713A3 EP 9902661 W EP9902661 W EP 9902661W WO 9954713 A3 WO9954713 A3 WO 9954713A3
Authority
WO
WIPO (PCT)
Prior art keywords
detector
surface plasmon
plasmon resonance
shift
detecting
Prior art date
Application number
PCT/EP1999/002661
Other languages
German (de)
French (fr)
Other versions
WO1999054713A2 (en
Inventor
Gunnar Brink
Henning Groll
Jakob Tittel
Christof Rosner
Original Assignee
Biotul Ag
Gunnar Brink
Henning Groll
Jakob Tittel
Christof Rosner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotul Ag, Gunnar Brink, Henning Groll, Jakob Tittel, Christof Rosner filed Critical Biotul Ag
Priority to AU39279/99A priority Critical patent/AU3927999A/en
Publication of WO1999054713A2 publication Critical patent/WO1999054713A2/en
Publication of WO1999054713A3 publication Critical patent/WO1999054713A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention relates to a device for detecting a shift in a surface plasmon resonance, comprising a light source (1), a surface plasmon resonance transducer (2), a detector system (3) and an evaluation unit (4). The detector system comprises at least one pair of detector sections consisting of a first detector section and a second detector section. The first detector section is arranged at a distance from the second detector section and each detector section generates a signal (11, 12). The position of the detector system in relation to the light reflected by the surface plasmon resonance transducer is selected such that the evaluation unit can determine the position and shift of a surface plasmon resonance from the combination of the signals generated by the two detector sections.
PCT/EP1999/002661 1998-04-20 1999-04-20 Device and method for detecting a shift in a surface plasmon resonance WO1999054713A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU39279/99A AU3927999A (en) 1998-04-20 1999-04-20 Device and method for detecting a shift in a surface plasmon resonance

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19817472A DE19817472A1 (en) 1998-04-20 1998-04-20 Apparatus for detecting shift in surface plasma resonance in biological sensor systems
DE19817472.1 1998-04-20

Publications (2)

Publication Number Publication Date
WO1999054713A2 WO1999054713A2 (en) 1999-10-28
WO1999054713A3 true WO1999054713A3 (en) 2000-03-23

Family

ID=7865122

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/002661 WO1999054713A2 (en) 1998-04-20 1999-04-20 Device and method for detecting a shift in a surface plasmon resonance

Country Status (3)

Country Link
AU (1) AU3927999A (en)
DE (1) DE19817472A1 (en)
WO (1) WO1999054713A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10163657B4 (en) * 2001-12-21 2008-05-08 Gedig, Erk, Dr. Apparatus and method for investigating thin films
US9632022B2 (en) 2012-03-05 2017-04-25 Biosurfit S.A. Enhanced Surface Plasmon Resonance method
CN106338497B (en) * 2016-09-13 2019-02-22 南京大学 A surface plasmon resonance microscopy imaging device and method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5640245A (en) * 1994-06-01 1997-06-17 Laserspec Analytik Gmbh Spectroscopic method with double modulation
JPH09292334A (en) * 1996-04-30 1997-11-11 Fuji Photo Film Co Ltd Surface plasmon sensor
DE19650899A1 (en) * 1996-12-07 1998-06-18 Gunnar Dr Brink Optical sensors using tunable laser diodes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9120000D0 (en) * 1991-09-19 1991-11-06 British Gas Plc Optical sensing

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5640245A (en) * 1994-06-01 1997-06-17 Laserspec Analytik Gmbh Spectroscopic method with double modulation
JPH09292334A (en) * 1996-04-30 1997-11-11 Fuji Photo Film Co Ltd Surface plasmon sensor
US5875032A (en) * 1996-04-30 1999-02-23 Fuji Photo Film Co., Ltd. Surface plasmon sensor having an improved optical system
DE19650899A1 (en) * 1996-12-07 1998-06-18 Gunnar Dr Brink Optical sensors using tunable laser diodes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KRUCHININ A A ET AL: "Surface plasmon resonance monitoring by means of polarization state measurement in reflected light as the basis of a DNA-probe biosensor", SENSORS AND ACTUATORS B (CHEMICAL), vol. B30, no. 1, 1 January 1996 (1996-01-01), ISSN 0925-4005, pages 77 - 80, XP000584898 *
NELSON S G ET AL: "High sensitivity surface plasmon resonance sensor based on phase detection", SENSORS AND ACTUATORS B (CHEMICAL), vol. B35, no. 1-3, September 1996 (1996-09-01), ISSN 0925-4005, pages 187 - 191, XP000641397, ISSN: 0925-4005 *
PETERLINZ A ET AL: "Two-color approach for determination of thickness and dielectric constant of thin films using surface plasmon resonance spectroscopy", OPTICS COMMUNICATIONS, vol. 130, no. 4-6, 1 October 1996 (1996-10-01), ISSN 0030-4018, pages 260 - 266, XP000627753 *

Also Published As

Publication number Publication date
DE19817472A1 (en) 1999-10-28
AU3927999A (en) 1999-11-08
WO1999054713A2 (en) 1999-10-28

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