+

WO1999054466A3 - Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques - Google Patents

Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques Download PDF

Info

Publication number
WO1999054466A3
WO1999054466A3 PCT/US1999/008672 US9908672W WO9954466A3 WO 1999054466 A3 WO1999054466 A3 WO 1999054466A3 US 9908672 W US9908672 W US 9908672W WO 9954466 A3 WO9954466 A3 WO 9954466A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnostic
colon cancer
associated antigens
therapeutic uses
cancer
Prior art date
Application number
PCT/US1999/008672
Other languages
English (en)
Other versions
WO1999054466A2 (fr
Inventor
Fei Huang
Paul B Fisher
Neil I Goldstein
Original Assignee
Fei Huang
Paul B Fisher
Neil I Goldstein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fei Huang, Paul B Fisher, Neil I Goldstein filed Critical Fei Huang
Priority to AU37534/99A priority Critical patent/AU3753499A/en
Publication of WO1999054466A2 publication Critical patent/WO1999054466A2/fr
Publication of WO1999054466A3 publication Critical patent/WO1999054466A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des compositions et des méthodes de dépistage du cancer et de thérapie anticancéreuse. Ces composés comportent des protéines associées aux tumeurs, des parties de celles-ci et leurs variants, ainsi que des polynucléotides codant de tels polypeptides. L'invention concerne également des vaccins et des compositions pharmaceutiques qui comprennent ces composés et qui peuvent être utilisés, par exemple, pour la prévention et le traitement du cancer. Ces polypeptides peuvent également être utilisés pour la production d'anticorps utiles pour diagnostiquer et surveiller l'évolution du cancer chez un patient.
PCT/US1999/008672 1998-04-20 1999-04-20 Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques WO1999054466A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU37534/99A AU3753499A (en) 1998-04-20 1999-04-20 Colon cancer-associated antigens and their diagnostic and therapeutic uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8244198P 1998-04-20 1998-04-20
US60/082,441 1998-04-20

Publications (2)

Publication Number Publication Date
WO1999054466A2 WO1999054466A2 (fr) 1999-10-28
WO1999054466A3 true WO1999054466A3 (fr) 2000-02-17

Family

ID=22171243

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/008672 WO1999054466A2 (fr) 1998-04-20 1999-04-20 Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques

Country Status (2)

Country Link
AU (1) AU3753499A (fr)
WO (1) WO1999054466A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002008288A2 (fr) * 2000-07-20 2002-01-31 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
AU6531101A (en) * 2000-06-02 2001-12-17 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP2591786B1 (fr) * 2003-10-16 2017-04-12 Cancure Limited Compositions immunomodulatrices et leurs utilisations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003422A1 (fr) * 1993-07-22 1995-02-02 Ludwig Institute For Cancer Research Methode de diagnostic d'une anomalie par mise en evidence de l'expression des precurseurs gage des antigenes de rejet des tumeurs
DE19547529A1 (de) * 1995-12-10 1997-06-12 Reutter Werner Prof Dr Med Hybridomzellklone, die monoklonale Antikörper synthetisieren mit hoher Selektivität und Spezifität für Dickdarmkarzinomzellen mit einem Antigen vom Molekulargewicht 70k; ihre Anwendung in Diagnostik und Therapie

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003422A1 (fr) * 1993-07-22 1995-02-02 Ludwig Institute For Cancer Research Methode de diagnostic d'une anomalie par mise en evidence de l'expression des precurseurs gage des antigenes de rejet des tumeurs
DE19547529A1 (de) * 1995-12-10 1997-06-12 Reutter Werner Prof Dr Med Hybridomzellklone, die monoklonale Antikörper synthetisieren mit hoher Selektivität und Spezifität für Dickdarmkarzinomzellen mit einem Antigen vom Molekulargewicht 70k; ihre Anwendung in Diagnostik und Therapie

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL - EMEST18 13 June 1997 (1997-06-13), MARRA, M. ET AL.: "vf89e05.r1 Soares mouse mammary gland NbMMG Mus musculus cDNA clone 850976 5'.", XP002111975 *
DATABASE EMBL - R57U053 9 February 1999 (1999-02-09), NAGASE, T. ET AL.: "Homo sapiens mRNA for KIAA0826 protein, partial cds.", XP002111976 *
GRIMM T ET AL: "A modified screening method for pcDNA-1 expression libraries which is applicable to both surface and intracellular antigens Cloning of a colon carcinoma antigen", JOURNAL OF IMMUNOLOGICAL METHODS, vol. 186, no. 2, 16 October 1995 (1995-10-16), pages 305-312, XP004021231, ISSN: 0022-1759 *
NAGASE, T. ET AL.: "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.", DNA RESEARCH, vol. 5, December 1998 (1998-12-01), pages 355 - 64, XP002111974 *
VAN BELZEN N ET AL: "Detection of different gene expression in differentiating colon carcinoma cells by differential display", JOURNAL OF PATHOLOGY, vol. 178, 1 January 1996 (1996-01-01), pages 2A, XP002089886, ISSN: 0022-3417 *
VEILLETTE A ET AL: "EXPRESSION OF THE LCK TYROSINE KINASE GENE IN HUMAN COLON CARCINOMA AND OTHER NON-LYMPHOID HUMAN TUMOR CELL LINES", ONCOGENE RESEARCH, vol. 1, 1987, pages 357 - 374, XP002912135 *

Also Published As

Publication number Publication date
WO1999054466A2 (fr) 1999-10-28
AU3753499A (en) 1999-11-08

Similar Documents

Publication Publication Date Title
WO1997025426A3 (fr) Compositions et procedes pour le traitement et le diagnostic du cancer du sein
WO2002006317A3 (fr) Compositions et procedes utilises dans la therapie et le diagnostic du cancer des ovaires
WO2000036107A3 (fr) Compositions et procedes destines a la therapie et au diagnostic du cancer de l"ovaire
WO1999033869A3 (fr) Composes destines a l'immunotherapie et au diagnostic du cancer du sein, et leur mode d'utilisation
NO20004631L (no) Forbindelser og fremgangsmÕter for terapi og diagnose av lungekreft
WO2000061612A3 (fr) Composes et procedes de therapie et de diagnostic du cancer du poumon
WO1999038973A3 (fr) Composes destines au diagnostic et a la therapie du cancer du poumon et procedes d'utilisation associes
WO1998045328A3 (fr) Compositions therapeutiques et diagnostiques du carcinome mammaire et methodes afferentes
WO2002074156A8 (fr) Compositions et procedes de therapie et de diagnostic du cancer du colon
WO2002016413A8 (fr) Vaccins
WO2002060317A3 (fr) Compositions et methodes pour le traitement et le diagnostic du cancer du pancreas
WO2002092001A3 (fr) Compositions et methodes de traitement et de diagnostic du cancer du poumon
WO2002074237A8 (fr) Compositions et procedes de therapie et de diagnostic du cancer du rein
WO2002078516A3 (fr) Compositions et methodes de traitement et de diagnostic de cancers
WO2002058534A3 (fr) Compositions et methodes pour le traitement et le diagnostic du cancer du colon
WO2003037267A8 (fr) Compositions et methodes de traitement et de diagnostic du cancer des poumons
WO2001018046A3 (fr) Sequences de tumeurs ovariennes et procedes d'utilisation correspondants
WO2000061756A3 (fr) Composes pour l'immunotherapie et le diagnostic du cancer du sein et procedes d'utilisation
WO2003013431A3 (fr) Compositions et techniques de therapie et de diagnostic du cancer du sein
WO2001090152A3 (fr) Compositions et procedes pour la therapie et le diagnostic du cancer du sein
WO1999037775A3 (fr) Compositions et procedes pour la detection et le traitement du cancer du sein
WO2000061753A3 (fr) Compositions et methodes de depistage et de traitement du cancer du sein
WO1999054466A3 (fr) Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques
EP1351967A4 (fr) Compositions et procedes pour la therapie et le diagnostic du cancer des poumons
WO1999037778A3 (fr) Compositions et procedes de detection et de traitement du cancer de la prostate

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
NENP Non-entry into the national phase

Ref country code: KR

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载