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WO1999050385A3 - Regulation de la synthese de glycosaminoglycane, techniques apparentees et reactifs connexes - Google Patents

Regulation de la synthese de glycosaminoglycane, techniques apparentees et reactifs connexes Download PDF

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Publication number
WO1999050385A3
WO1999050385A3 PCT/US1999/006892 US9906892W WO9950385A3 WO 1999050385 A3 WO1999050385 A3 WO 1999050385A3 US 9906892 W US9906892 W US 9906892W WO 9950385 A3 WO9950385 A3 WO 9950385A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
methods
hedgehog
glycosaminoglycan synthesis
reagents related
Prior art date
Application number
PCT/US1999/006892
Other languages
English (en)
Other versions
WO1999050385A2 (fr
Inventor
Yohanns Bellaiche
Siu Inge The
Norbert Perrimon
Original Assignee
Harvard College
Yohanns Bellaiche
Siu Inge
Norbert Perrimon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College, Yohanns Bellaiche, Siu Inge, Norbert Perrimon filed Critical Harvard College
Priority to AU33710/99A priority Critical patent/AU3371099A/en
Publication of WO1999050385A2 publication Critical patent/WO1999050385A2/fr
Publication of WO1999050385A3 publication Critical patent/WO1999050385A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Cette invention a trait à la découverte d'une nouvelle famille de protéines interactives hérisson, dénommées dans le descriptif 'protéines interactives hérisson' ou 'Exts'. Il y est démontré que ces protéines se fixent à des polypeptides hérisson et ce, avec une affinité élevée. Ces protéines sont nécessaires à la diffusion des polypeptides hérisson et, à ce titre, à leur régulation.
PCT/US1999/006892 1998-03-30 1999-03-30 Regulation de la synthese de glycosaminoglycane, techniques apparentees et reactifs connexes WO1999050385A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU33710/99A AU3371099A (en) 1998-03-30 1999-03-30 Regulation of glycosaminoglycan synthesis, methods and reagents related thereto

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7992898P 1998-03-30 1998-03-30
US60/079,928 1998-03-30

Publications (2)

Publication Number Publication Date
WO1999050385A2 WO1999050385A2 (fr) 1999-10-07
WO1999050385A3 true WO1999050385A3 (fr) 1999-11-18

Family

ID=22153704

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/006892 WO1999050385A2 (fr) 1998-03-30 1999-03-30 Regulation de la synthese de glycosaminoglycane, techniques apparentees et reactifs connexes

Country Status (2)

Country Link
AU (1) AU3371099A (fr)
WO (1) WO1999050385A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1228069B1 (fr) 1999-11-12 2003-04-02 Neurogen Corporation Composes heteroaromatiques bicycliques et tricycliques
WO2002088081A2 (fr) 2001-05-01 2002-11-07 The Regents Of The University Of California Recepteurs wnt et frizzled utilises comme cibles en immunotherapie contre un carcinome spinocellulaire cervico-facial
WO2004100961A1 (fr) 2003-05-19 2004-11-25 Seikagaku Corporation Inhibiteur de transférase de groupe sulfate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009037A1 (fr) * 1992-10-15 1994-04-28 New York University Medical Center NOUVELLE CLASSE DE RPTPases: LEURS DOMAINES STRUCTURAUX ET LIGANDS
US5541095A (en) * 1992-06-16 1996-07-30 University Of Massachusetts Medical Center Glycosaminoglycan specific sulfotransferases
WO1998030576A1 (fr) * 1996-10-07 1998-07-16 The Johns Hopkins University School Of Medicine Nouveaux polypeptides derives d'une proteine herisson
WO1998052553A1 (fr) * 1997-05-21 1998-11-26 Johns Hopkins University Procedes de traitement d'etats associes au lactosylceramide

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541095A (en) * 1992-06-16 1996-07-30 University Of Massachusetts Medical Center Glycosaminoglycan specific sulfotransferases
WO1994009037A1 (fr) * 1992-10-15 1994-04-28 New York University Medical Center NOUVELLE CLASSE DE RPTPases: LEURS DOMAINES STRUCTURAUX ET LIGANDS
WO1998030576A1 (fr) * 1996-10-07 1998-07-16 The Johns Hopkins University School Of Medicine Nouveaux polypeptides derives d'une proteine herisson
WO1998052553A1 (fr) * 1997-05-21 1998-11-26 Johns Hopkins University Procedes de traitement d'etats associes au lactosylceramide

Also Published As

Publication number Publication date
WO1999050385A2 (fr) 1999-10-07
AU3371099A (en) 1999-10-18

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