WO1999046391A3 - Prostate derived serine protease (pdsp) protein and nucleic acid molecules and uses therefor - Google Patents
Prostate derived serine protease (pdsp) protein and nucleic acid molecules and uses therefor Download PDFInfo
- Publication number
- WO1999046391A3 WO1999046391A3 PCT/US1999/005416 US9905416W WO9946391A3 WO 1999046391 A3 WO1999046391 A3 WO 1999046391A3 US 9905416 W US9905416 W US 9905416W WO 9946391 A3 WO9946391 A3 WO 9946391A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pdsp
- nucleic acid
- acid molecules
- protein
- serine protease
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 102000012479 Serine Proteases Human genes 0.000 title 1
- 108010022999 Serine Proteases Proteins 0.000 title 1
- 210000002307 prostate Anatomy 0.000 title 1
- 239000013604 expression vector Substances 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 238000003259 recombinant expression Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Novel PDSP polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length PDSP proteins, the invention further provides isolated PDSP fusion proteins, antigenic peptides and anti-PDSP antibodies. The invention also provides PDSP nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a PDSP gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU33541/99A AU3354199A (en) | 1998-03-12 | 1999-03-12 | Prostate derived serine protease (pdsp) protein and nucleic acid molecules and uses therefor |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4140098A | 1998-03-12 | 1998-03-12 | |
| US09/041,400 | 1998-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1999046391A2 WO1999046391A2 (en) | 1999-09-16 |
| WO1999046391A3 true WO1999046391A3 (en) | 1999-10-21 |
Family
ID=21916323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1999/005416 WO1999046391A2 (en) | 1998-03-12 | 1999-03-12 | Prostate derived serine protease (pdsp) protein and nucleic acid molecules and uses therefor |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU3354199A (en) |
| WO (1) | WO1999046391A2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2000257489A1 (en) * | 2000-06-20 | 2002-01-02 | Human Genome Sciences, Inc. | Polynucleotides encoding human serine proteases |
| WO2001098467A2 (en) * | 2000-06-23 | 2001-12-27 | Bayer Aktiengesellschaft | Regulation of human prostasin-like serine protease |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998042849A1 (en) * | 1997-03-26 | 1998-10-01 | Incyte Pharmaceuticals, Inc. | Keratinocyte derived kallikrein |
| WO1999018219A1 (en) * | 1997-10-03 | 1999-04-15 | The Procter & Gamble Company | A keratinocyte derived protease |
| WO1999022027A1 (en) * | 1997-10-28 | 1999-05-06 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
-
1999
- 1999-03-12 WO PCT/US1999/005416 patent/WO1999046391A2/en active Application Filing
- 1999-03-12 AU AU33541/99A patent/AU3354199A/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998042849A1 (en) * | 1997-03-26 | 1998-10-01 | Incyte Pharmaceuticals, Inc. | Keratinocyte derived kallikrein |
| WO1999018219A1 (en) * | 1997-10-03 | 1999-04-15 | The Procter & Gamble Company | A keratinocyte derived protease |
| WO1999022027A1 (en) * | 1997-10-28 | 1999-05-06 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
Non-Patent Citations (2)
| Title |
|---|
| EMBL/GENBANK DATABASES Accession no W73140 Sequence reference HS140444 20 June 1996 HILLIER L ET AL: "The WashU-Merck EST Project" * |
| EMBL/GENBANK DATABASES Accession no W73168 Sequence reference HS168367 20 June 1996 HILLIER L ET AL: "The WashU-Merck EST Project" * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU3354199A (en) | 1999-09-27 |
| WO1999046391A2 (en) | 1999-09-16 |
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| DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
| 122 | Ep: pct application non-entry in european phase |