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WO1999046379A3 - Human receptor proteins; related reagents and methods - Google Patents

Human receptor proteins; related reagents and methods Download PDF

Info

Publication number
WO1999046379A3
WO1999046379A3 PCT/US1999/003735 US9903735W WO9946379A3 WO 1999046379 A3 WO1999046379 A3 WO 1999046379A3 US 9903735 W US9903735 W US 9903735W WO 9946379 A3 WO9946379 A3 WO 9946379A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
receptor proteins
human receptor
related reagents
reagents
Prior art date
Application number
PCT/US1999/003735
Other languages
French (fr)
Other versions
WO1999046379A2 (en
Inventor
Christi L Parham
Kevin W Moore
Nicholas J Murgolo
J Fernando Bazan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to JP2000535746A priority Critical patent/JP2002505879A/en
Priority to EP99909534A priority patent/EP1062332A2/en
Priority to CA002323236A priority patent/CA2323236A1/en
Priority to AU28718/99A priority patent/AU2871899A/en
Publication of WO1999046379A2 publication Critical patent/WO1999046379A2/en
Publication of WO1999046379A3 publication Critical patent/WO1999046379A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Nucleic acids encoding mammalian, e.g., primate or rodent receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
PCT/US1999/003735 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods WO1999046379A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000535746A JP2002505879A (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods
EP99909534A EP1062332A2 (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods
CA002323236A CA2323236A1 (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods
AU28718/99A AU2871899A (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3739498A 1998-03-09 1998-03-09
US09/037,394 1998-03-09

Publications (2)

Publication Number Publication Date
WO1999046379A2 WO1999046379A2 (en) 1999-09-16
WO1999046379A3 true WO1999046379A3 (en) 1999-10-21

Family

ID=21894109

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/003735 WO1999046379A2 (en) 1998-03-09 1999-03-08 Human receptor proteins; related reagents and methods

Country Status (5)

Country Link
EP (1) EP1062332A2 (en)
JP (1) JP2002505879A (en)
AU (1) AU2871899A (en)
CA (1) CA2323236A1 (en)
WO (1) WO1999046379A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
JP4741139B2 (en) * 1999-12-23 2011-08-03 ザイモジェネティクス， インコーポレイテッド Soluble interleukin-20 receptor
US7122632B2 (en) 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
EP1616575B1 (en) * 1999-12-23 2012-06-06 ZymoGenetics, Inc. Method for treating inflammation
EP1717316B1 (en) 2000-06-30 2008-08-13 ZymoGenetics, Inc. Allelic variant of the Interferon-like protein ZCYTO21
ATE547525T1 (en) 2000-08-08 2012-03-15 Zymogenetics Inc SOLUBLE ZCYCTOR 11 CYTOKINE RECEPTORS
AU2001290837A1 (en) 2000-09-15 2002-03-26 Zymogenetics Inc. Use of a polypeptide comprising the extracellular domains of il-20rb for the treatment of inflammation
WO2003029262A2 (en) * 2001-08-29 2003-04-10 Vanderbilt University The human mob-5 (il-24) receptors and uses thereof
DK1531843T3 (en) 2001-12-17 2011-12-12 Zymogenetics Inc Method of treating cervical cancer
DK1606317T3 (en) 2003-03-24 2010-10-25 Zymogenetics Inc Anti-IL-22RA antibodies and binding partners as well as methods of use in inflammation
DE602004012424T2 (en) 2003-08-07 2009-04-30 Zymogenetics, Inc., Seattle HOMOGENEOUS PREPARATIONS OF IL-29
WO2005052001A2 (en) 2003-11-21 2005-06-09 Zymogenetics, Inc. Anti-il-20 receptor antibodies and binding partners and methods of using in inflammation
CN101198625A (en) 2004-10-22 2008-06-11 津莫吉尼蒂克斯公司 Anti-IL-22RA antibodies and binding partners and methods of using in inflammation
CN107496917B (en) 2010-02-26 2021-06-11 诺沃—诺迪斯克有限公司 Compositions comprising stable antibodies
RS66182B1 (en) 2010-05-28 2024-12-31 Novo Nordisk As Stable multi-dose compositions comprising an antibody and a preservative

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (en) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Accessory factor function for interferon gamma and its receptor
WO1995016036A2 (en) * 1993-12-09 1995-06-15 Michel Aguet IFN-ηRECEPTOR β-CHAIN AND DERIVATIVES THEREOF

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005847A1 (en) * 1993-08-20 1995-03-02 University Of Medicine & Dentistry Of New Jersey Accessory factor function for interferon gamma and its receptor
WO1995016036A2 (en) * 1993-12-09 1995-06-15 Michel Aguet IFN-ηRECEPTOR β-CHAIN AND DERIVATIVES THEREOF

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002112563, Database accession no. AA455558 *
HEMMI S. ET AL.: "A novel member of the Interferon Receptor family complements functionality of the murine Interferon gamma Receptor in human cells", CELL, vol. 76, 11 March 1994 (1994-03-11), pages 803 - 810, XP002112561 *
PESTKA S.: "The Interferon Receptors", SEMINARS IN ONCOLOGY, vol. 24, no. 3 suppl. 9, June 1997 (1997-06-01), pages S9-18 - S9-40, XP002113151 *
SOH J. ET AL.: "Identification and sequence of an accessory factor required for activation of the human Interferon gamma Receptor", CELL, vol. 76, 11 March 1994 (1994-03-11), pages 793 - 802, XP002067347, ISSN: 0092-8674 *
ZUKER C. ET AL.: "Dictyostelium transposable element DIRS-1 has 350-base-pair inverted terminal repeats that contain a heat shock promoter", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE USA, vol. 81, May 1984 (1984-05-01), pages 2660 - 2664, XP002112562 *

Also Published As

Publication number Publication date
WO1999046379A2 (en) 1999-09-16
JP2002505879A (en) 2002-02-26
CA2323236A1 (en) 1999-09-16
EP1062332A2 (en) 2000-12-27
AU2871899A (en) 1999-09-27

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