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WO1998038211A3 - Permuted hemoglobin-like proteins - Google Patents

Permuted hemoglobin-like proteins Download PDF

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Publication number
WO1998038211A3
WO1998038211A3 PCT/US1998/003836 US9803836W WO9838211A3 WO 1998038211 A3 WO1998038211 A3 WO 1998038211A3 US 9803836 W US9803836 W US 9803836W WO 9838211 A3 WO9838211 A3 WO 9838211A3
Authority
WO
WIPO (PCT)
Prior art keywords
hemoglobin
permuted
proteins
termini
novel
Prior art date
Application number
PCT/US1998/003836
Other languages
French (fr)
Other versions
WO1998038211A2 (en
Inventor
Elaine A Best
Peter O Olins
Original Assignee
Somatogen Inc
Elaine A Best
Peter O Olins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somatogen Inc, Elaine A Best, Peter O Olins filed Critical Somatogen Inc
Priority to AU63409/98A priority Critical patent/AU6340998A/en
Publication of WO1998038211A2 publication Critical patent/WO1998038211A2/en
Publication of WO1998038211A3 publication Critical patent/WO1998038211A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides novel hemoglobin-like proteins that have permuted termini such that novel N- and C-termini are created. The new termini can be attached to functional polypeptides or other hemoglobin molecules to form multimeric hemoglobins.
PCT/US1998/003836 1997-02-28 1998-02-27 Permuted hemoglobin-like proteins WO1998038211A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63409/98A AU6340998A (en) 1997-02-28 1998-02-27 Permuted hemoglobin-like proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3965797P 1997-02-28 1997-02-28
US60/039,657 1997-02-28

Publications (2)

Publication Number Publication Date
WO1998038211A2 WO1998038211A2 (en) 1998-09-03
WO1998038211A3 true WO1998038211A3 (en) 1998-12-23

Family

ID=21906655

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/003836 WO1998038211A2 (en) 1997-02-28 1998-02-27 Permuted hemoglobin-like proteins

Country Status (2)

Country Link
AU (1) AU6340998A (en)
WO (1) WO1998038211A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007932A1 (en) * 1993-09-14 1995-03-23 Medical Research Council Improvements in or relating to haemoglobin
WO1996040920A1 (en) * 1992-11-06 1996-12-19 Somatogen, Inc. Modified hemoglobin-like compounds and methods of purifying same
WO1998013386A1 (en) * 1996-09-27 1998-04-02 The Board Of Trustees Of The University Of Illinois Oxygen-binding heme proteins incorporating circularly-permuted globins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996040920A1 (en) * 1992-11-06 1996-12-19 Somatogen, Inc. Modified hemoglobin-like compounds and methods of purifying same
WO1995007932A1 (en) * 1993-09-14 1995-03-23 Medical Research Council Improvements in or relating to haemoglobin
WO1998013386A1 (en) * 1996-09-27 1998-04-02 The Board Of Trustees Of The University Of Illinois Oxygen-binding heme proteins incorporating circularly-permuted globins

Also Published As

Publication number Publication date
AU6340998A (en) 1998-09-18
WO1998038211A2 (en) 1998-09-03

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