+

WO1998036732A3 - Combination preparation for orally administered antibiotics - Google Patents

Combination preparation for orally administered antibiotics Download PDF

Info

Publication number
WO1998036732A3
WO1998036732A3 PCT/EP1998/000029 EP9800029W WO9836732A3 WO 1998036732 A3 WO1998036732 A3 WO 1998036732A3 EP 9800029 W EP9800029 W EP 9800029W WO 9836732 A3 WO9836732 A3 WO 9836732A3
Authority
WO
WIPO (PCT)
Prior art keywords
component
orally administered
combination preparation
administered antibiotics
antibiotics
Prior art date
Application number
PCT/EP1998/000029
Other languages
German (de)
French (fr)
Other versions
WO1998036732A2 (en
Inventor
Ulrich Posanski
Original Assignee
Glf Galenik Labor Gmbh
Ulrich Posanski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glf Galenik Labor Gmbh, Ulrich Posanski filed Critical Glf Galenik Labor Gmbh
Priority to AU60926/98A priority Critical patent/AU6092698A/en
Priority to EP98905269A priority patent/EP0971691A2/en
Publication of WO1998036732A2 publication Critical patent/WO1998036732A2/en
Publication of WO1998036732A3 publication Critical patent/WO1998036732A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a combination product for the oral administration of antibiotics as an aqueous suspension, comprising a) an active ingredient component in the form of particles coated with a polymeric, permeable coating agent capable of swelling and/or soluble in gastric juice; and b) a syrup base with a pH between 5 and 10 as a second component which is spatially separate from the first component a). The two components are presented in two separate containers packaged in a combined pack in the form of a 'kit of parts'.
PCT/EP1998/000029 1997-02-21 1998-01-05 Combination preparation for orally administered antibiotics WO1998036732A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU60926/98A AU6092698A (en) 1997-02-21 1998-01-05 Combination preparation for orally administered antibiotics
EP98905269A EP0971691A2 (en) 1997-02-21 1998-01-05 Combination preparation for orally administered antibiotics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1997106978 DE19706978A1 (en) 1997-02-21 1997-02-21 Combination preparation for oral antibiotics
DE19706978.9 1997-02-21

Publications (2)

Publication Number Publication Date
WO1998036732A2 WO1998036732A2 (en) 1998-08-27
WO1998036732A3 true WO1998036732A3 (en) 1998-10-22

Family

ID=7821094

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/000029 WO1998036732A2 (en) 1997-02-21 1998-01-05 Combination preparation for orally administered antibiotics

Country Status (4)

Country Link
EP (1) EP0971691A2 (en)
AU (1) AU6092698A (en)
DE (1) DE19706978A1 (en)
WO (1) WO1998036732A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960356B1 (en) 1997-09-19 2005-11-01 Ranbaxy Laboratories Limited Orally administered drug delivery system providing temporal and spatial control

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551616B1 (en) 1997-04-11 2003-04-22 Abbott Laboratories Extended release formulations of erythromycin derivatives
GB9815532D0 (en) 1998-07-17 1998-09-16 Lek Pharmaceutical & Cvhemical Pharmaceutical suspension formulation
GB9930578D0 (en) * 1999-12-23 2000-02-16 Smithkline Beecham Plc Pharmaceutical formulations
IL161259A0 (en) * 2001-12-21 2004-09-27 Pfizer Prod Inc Methods for wet granulating azithromycin
CN103796638A (en) 2011-08-12 2014-05-14 勃林格殷格翰动物保健有限公司 Taste masked pharmaceutical composition
WO2014122248A1 (en) 2013-02-11 2014-08-14 Boehringer Ingelheim Vetmedica Gmbh Kit-of-parts

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069097A2 (en) * 1981-06-18 1983-01-05 Astra Läkemedel Aktiebolag Pharmaceutical mixture
GB2122490A (en) * 1982-06-24 1984-01-18 Astra Laekemedel Ab Controlled release formulation
WO1993000898A1 (en) * 1991-07-11 1993-01-21 Smithkline Beecham Plc Pharmaceutical formulation of a beta-lactam antibiotic and clavulanic acid or a water-soluble salt thereof
EP0551820A1 (en) * 1992-01-15 1993-07-21 Bayer Ag Taste-masked pharmaceutical compositions
WO1993017667A1 (en) * 1992-03-12 1993-09-16 Taisho Pharmaceutical Co., Ltd. Composition for oral preparations
WO1996001628A1 (en) * 1994-07-07 1996-01-25 Recordati Industria Chimica E Farmaceutica S.P.A. Pharmaceutical composition for the controlled release of moguisteine in a liquid suspension

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0069097A2 (en) * 1981-06-18 1983-01-05 Astra Läkemedel Aktiebolag Pharmaceutical mixture
GB2122490A (en) * 1982-06-24 1984-01-18 Astra Laekemedel Ab Controlled release formulation
WO1993000898A1 (en) * 1991-07-11 1993-01-21 Smithkline Beecham Plc Pharmaceutical formulation of a beta-lactam antibiotic and clavulanic acid or a water-soluble salt thereof
EP0551820A1 (en) * 1992-01-15 1993-07-21 Bayer Ag Taste-masked pharmaceutical compositions
WO1993017667A1 (en) * 1992-03-12 1993-09-16 Taisho Pharmaceutical Co., Ltd. Composition for oral preparations
WO1996001628A1 (en) * 1994-07-07 1996-01-25 Recordati Industria Chimica E Farmaceutica S.P.A. Pharmaceutical composition for the controlled release of moguisteine in a liquid suspension

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960356B1 (en) 1997-09-19 2005-11-01 Ranbaxy Laboratories Limited Orally administered drug delivery system providing temporal and spatial control

Also Published As

Publication number Publication date
WO1998036732A2 (en) 1998-08-27
AU6092698A (en) 1998-09-09
EP0971691A2 (en) 2000-01-19
DE19706978A1 (en) 1998-08-27

Similar Documents

Publication Publication Date Title
CA2251886A1 (en) An oral pharmaceutical formulation containing ibandronate
CA2253811A1 (en) Taste masked liquid suspensions
CA2180816A1 (en) 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
CA2193337A1 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
CA2163706A1 (en) Amino Acid Derivatives of Paclitaxel
CA2170622A1 (en) Oral Formulations of an Antifungal
CA2426956A1 (en) Pharmaceutical compositions comprising ascomycin derivatives
CA2258095A1 (en) Tetrahydrolipstatin containing compositions
CA2037101A1 (en) Omeprazole Compositions Designed for Administration in Rectum
CA2203033A1 (en) Compounds and compositions for delivering active agents
CA2311450A1 (en) Pharmaceutical aerosol compositions
CA2337046A1 (en) Sustained release pharmaceutical preparation
IE881452L (en) Pharmaceutical composition
EP1731140A3 (en) Medicinal aerosol formulation
CA2024631A1 (en) Double-coated granules of disodium pamidronate
AU3345197A (en) Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof
HUP9800813A3 (en) Lactam-containing hydroxamic acid derivatives, their preparation and pharmaceutical compositions containing them
AU5651696A (en) Substituted 1-phenyl-3-pyrazolecarboxamides active on nurotensin receptors, their preparation and pharmaceutical compositions containing them
CA2299420A1 (en) Pharmaceutical compositions containing vitamin d and calcium, their preparation and therapeutic use
CA2164776A1 (en) Pharmaceutical, orally applicable composition
CA2175971A1 (en) Stable liquid composition containing urate oxidase and lyophilized composition for its preparation
CA2338794A1 (en) New oral formulation for 5-ht4 agonists or antagonists
AU7694896A (en) Prompt-release pharmaceutical compositions
WO1998036732A3 (en) Combination preparation for orally administered antibiotics
CA2376894A1 (en) Pharmaceutical composition comprising a protein and an ectoine

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM GW HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1998905269

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1998905269

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 1998536182

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 1998905269

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载