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WO1998031712A3 - Chitosan-conjugates with acidic chelate-complex forming agents - Google Patents

Chitosan-conjugates with acidic chelate-complex forming agents Download PDF

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Publication number
WO1998031712A3
WO1998031712A3 PCT/EP1998/000320 EP9800320W WO9831712A3 WO 1998031712 A3 WO1998031712 A3 WO 1998031712A3 EP 9800320 W EP9800320 W EP 9800320W WO 9831712 A3 WO9831712 A3 WO 9831712A3
Authority
WO
WIPO (PCT)
Prior art keywords
conjugates
chitosan
forming agents
complex forming
acidic chelate
Prior art date
Application number
PCT/EP1998/000320
Other languages
French (fr)
Other versions
WO1998031712A2 (en
Inventor
Andreas Bernkop-Schnuerch
Christina Paikl
Original Assignee
Goodrich Co B F
Bernkop Schnuerch Andreas
Christina Paikl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goodrich Co B F, Bernkop Schnuerch Andreas, Christina Paikl filed Critical Goodrich Co B F
Priority to EP98907971A priority Critical patent/EP0954537A2/en
Publication of WO1998031712A2 publication Critical patent/WO1998031712A2/en
Publication of WO1998031712A3 publication Critical patent/WO1998031712A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

The present invention relates to chitosan-conjugates with acidic chelate-complex forming agents, their method of manufacture and their use in the pharmaceutical and cosmetic fields.
PCT/EP1998/000320 1997-01-21 1998-01-21 Chitosan-conjugates with acidic chelate-complex forming agents WO1998031712A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP98907971A EP0954537A2 (en) 1997-01-21 1998-01-21 Chitosan-conjugates with acidic chelate-complex forming agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0007997A ATA7997A (en) 1997-01-21 1997-01-21 METHOD FOR PRODUCING CHITOSAN ETHYLENE DIAMINE TETRAACETATE CONJUGATES
ATA79/97 1997-01-21

Publications (2)

Publication Number Publication Date
WO1998031712A2 WO1998031712A2 (en) 1998-07-23
WO1998031712A3 true WO1998031712A3 (en) 1998-09-11

Family

ID=3480978

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/000320 WO1998031712A2 (en) 1997-01-21 1998-01-21 Chitosan-conjugates with acidic chelate-complex forming agents

Country Status (3)

Country Link
EP (1) EP0954537A2 (en)
AT (1) ATA7997A (en)
WO (1) WO1998031712A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000086538A (en) * 1998-09-17 2000-03-28 Toshihiro Akaike Contrast medium for mri
ATA13842001A (en) 2001-08-31 2002-10-15 Mucobiomer Biotechnologische F CHITOSAN-THIO-ALKYL-AMIDINE CONJUGATES AND THEIR COSMETIC AND PHARMACEUTICAL USE
US6896809B2 (en) 2002-12-20 2005-05-24 Providence Health System - Oregon Methods for purifying chitosan
US9198997B2 (en) 2008-04-24 2015-12-01 Medtronic, Inc. Rehydratable thiolated polysaccharide particles and sponge
US8802652B2 (en) 2008-04-24 2014-08-12 Medtronic, Inc. Rehydratable polysaccharide particles and sponge
CA2721937C (en) 2008-04-24 2016-07-12 Medtronic, Inc. Protective gel based on chitosan and oxidized polysaccharide
WO2009132228A1 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Chitosan-containing protective composition
WO2014102741A2 (en) 2012-12-28 2014-07-03 University Of The Witwatersrand, Johannesburg Pharmaceutical dosage form
CL2015001254A1 (en) * 2015-05-08 2015-09-11 Cyra Consultora Limitada Chelating arsenic composition.

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
A. BERNKOP-SCHNÜRCH ET AL.: "Intestinal peptide and protein delivery: Synthesis and evaluation of a chitosan-inhibitor conjugate", FARM VESTN, vol. 48, 1997, pages 218 - 219, XP002069753 *
A. BERNKOP-SCHNÜRCH ET AL.: "Novel bioadhesive chitosan-edta conjugate rotects leucine enkephalin from degradation by aminopeptidase N", PHARMACEUTICAL RESEARCH, vol. 14, no. 7, July 1997 (1997-07-01), pages 917 - 922, XP002069752 *
C. VALENTA ET AL.: "Chitosan-EDTA conjugate: A novel polymer for topical used gels", FARM VESTN, vol. 48, 1997, pages 354 - 355, XP002069754 *
CHEMICAL ABSTRACTS, vol. 123, no. 16, 16 October 1995, Columbus, Ohio, US; abstract no. 217120, "Adsorption behaviors of some metal ions on chitosan modified with edta-type ligand" XP002069755 *
CHEMICAL ABSTRACTS, vol. 124, no. 24, 10 June 1996, Columbus, Ohio, US; abstract no. 320011, "adsorption behaviors of some complexane types of chemically modified chitosan for metal ions" XP002069756 *
INOUE K. ET AL., ADV. CHITIN SCI., vol. 1, 1996, pages 271 - 278 *
INOUE K. ET AL., BUNSEKI KAGAKU, vol. 44, no. 4, 1995, JP, pages 283 - 287 *
V. E. TIKHONOV ET AL.: "Metal-chelating chitin derivatives via reaction of chitosan with nitrilotriacetic acid", CARBOHYDRATE RESEARCH, vol. 290, 1996, pages 33 - 41, XP000596065 *

Also Published As

Publication number Publication date
ATA7997A (en) 1998-03-15
WO1998031712A2 (en) 1998-07-23
EP0954537A2 (en) 1999-11-10

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