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WO1998020749A1 - Preparation nutritive aqueuse contenant un acide lactique, un acide organique et des oligo-elements chelates - Google Patents

Preparation nutritive aqueuse contenant un acide lactique, un acide organique et des oligo-elements chelates Download PDF

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Publication number
WO1998020749A1
WO1998020749A1 PCT/NL1997/000615 NL9700615W WO9820749A1 WO 1998020749 A1 WO1998020749 A1 WO 1998020749A1 NL 9700615 W NL9700615 W NL 9700615W WO 9820749 A1 WO9820749 A1 WO 9820749A1
Authority
WO
WIPO (PCT)
Prior art keywords
aqueous
nutritive preparation
weight
per cent
acid
Prior art date
Application number
PCT/NL1997/000615
Other languages
English (en)
Inventor
Adrianus Wilhelmus Johannes Kanters
Original Assignee
Minotara Corporation N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minotara Corporation N.V. filed Critical Minotara Corporation N.V.
Priority to AU49699/97A priority Critical patent/AU4969997A/en
Publication of WO1998020749A1 publication Critical patent/WO1998020749A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K30/00—Processes specially adapted for preservation of materials in order to produce animal feeding-stuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs

Definitions

  • the present invention relates to an aqueous nutritive preparation substantially with a base of lactic acid and/or derivates thereof and one or more organic acids and trace elements, to methods for preparing such a nutritive preparation, to the use of such a nutritive preparation in drinking water or in wet feed in intensive stock farming and to the drinking water or the wet feed thus obtained.
  • the present invention furthermore relates to the use of an aqueous nutritive preparation for treating hooves of animals.
  • a aqueous nutritive preparation of this kind which is used as an anti-microbic composition for inhibiting the growth of detrimental microbes, is known from international patent application WO 96/24248.
  • the anti-microbic component comprises 50 - 99.8% per cent by weight of a substituted or non-substituted C r C 4 -monocarboxyl ic acid, and about 0.2 - 30 per cent by weight of the ester of a substituted or non-substituted benzoic acid.
  • Formic acid, acetic acid, propionic acid, lactic acid and pyruvic acid are mentioned as suitable organic mono- carboxylic acids.
  • the composition may contain certain salts of magnesium, zinc and copper, depending on its use.
  • feed supplement for ruminants which feed supplement comprises a non- toxic hydroxy organic compound selected from lactic acid, a metal salt thereof or a monohydric alcohol, excluding ethanol , or a di, tri or higher polyhydric alcohol, and a synthetic source of nitrogen.
  • a non- toxic hydroxy organic compound selected from lactic acid, a metal salt thereof or a monohydric alcohol, excluding ethanol , or a di, tri or higher polyhydric alcohol, and a synthetic source of nitrogen.
  • lactic acid in an aqueous nutritive preparation to be used in animal feed is also known from British patent applications Nos. 2 001 233 and 2 055 034.
  • Japanese patent application JP 53 111 010 A relates to a stable sorbic acid suspension for use in improving the storage properties of drinks and foodstuffs. Besides sorbic acid the suspension may also contain lactic acid, citric acid and malic acid, for example.
  • European patent application No. 0 701 778 relates to a method for preserving foodstuffs and to the foodstuffs thus obtained, whereby such foodstuffs are mixed with an aqueous potassium sorbate solution and an aqueous solution of an acid, for example phosphoric acid, lactic acid or sulphuric acid by using an intensive admixing process.
  • a aqueous nutritive preparation which is used as a disinfectant for drinking water is also known from European patent application No. 0 711 253.
  • Benzoic acid, sorbic acid, propionic acid, formic acid, citric acid, tartaric acid, lactic acid, malic acid, acetic acid, ascorbic acid, hydrochloric acid, sulphuric acid, and also the salts, derivates and ester compounds and mixtures are mentioned as suitable agents for effecting a reduction of the germination index and stabilising drinking water.
  • a preferred agent consists of 0.1 - 10 g of sodium benzoate and 0.1 - 10 g of sorbic acid per litre of water.
  • the object of the present invention is therefore to provide an aqueous nutritive preparation substantially with a base of lactic acid and/or derivates thereof and one or more other organic acids and trace elements, which nutritive preparation obviates the above- described drawbacks.
  • the present invention as referred to in the introduction is characterized in that one or more trace elements selected from the group consisting of copper, zinc, phosphorus, manganese, magnesium, iodine, selenium and cobalt are present in a chelate bonding in an amount of 0.01 - 25 per cent by weight in said aqueous nutritive preparation. If this amount is more than 25 per cent by weight, the trace elements will no longer be soluble in water, as a result of which precipitation of the essential trace elements will occur as yet. With amounts smaller than 0.01 per cent by weight it is no longer possible to observe an advantageous effect of the addition of the trace elements in the chelate bonding.
  • trace elements are present in a chelate bonding leads to an enhanced stability of the trace elements in the final aqueous nutritive preparation in comparison with the aqueous nutritive preparations known from the prior art, in which nutritive preparations the trace elements are present in the salt form.
  • chelate is to understood to mean a compound which comprises at least two " attaching points " , which attaching points are oriented such that hexagonal or pentagonal ring structures can be formed.
  • the chelate-forming agents are indicated by the number of attaching points, thus bidentates (two attaching points), tridentates (three attaching points), quadridentates, pentadentates, hexadentates and the like can be distinguished.
  • a trace element may also have been chelated by using several chelating agents, however. Since the attaching points bind the trace element, the chelating agent enhances the stability of the trace element. The strong bond between the trace element and the chelating agents results in chelate bondings which comprise improved chemical properties in comparison with the free trace elements, in particular as regards the prevention of precipitation at a critical pH value.
  • the term derivates is understood to mean lactic acid compounds derived from lactic acid, that is salts, ester compounds, and also mixtures thereof.
  • the amount of lactic acid and/or derivates thereof is preferably 1 - 85 per cent by weight, if this amount is less than 1 per cent by weight, its effect as regards the inhibition of bacterial growth will be insufficient. If the amount is more than 85 per cent by weight, the nutritive preparation obtained will exhibit an unpleasant odour. In addition to that the viscosity of the agent will be high, as a result of which its processing will be problematic.
  • lactic acid has appeared to be a highly suitable carrier for preserving a liquid mixture of minerals, vitamins, amino acids and the like. Furthermore it has become apparent that lactic acid has a very favourable influence on the gastro-intestinal tract of animals. The fact is that the addition of lactic acid to drinking water in intensive stock forming has not caused diarrhea with the animals, whilst the addition of sulphuric acid, for example, has caused serious problems.
  • Lactic acid obtained by fermentation of lactic acid bacteria is a natural product, which provides an optimum intestinal flora, in particular in the small intestine. Another remarkable aspect is that lactic acid has a positive influence on the excretion of phosphate and nitrogen compounds by animals. A decreased excretion of these compounds benefits the environment.
  • the aqueous nutritive preparation according to the present invention is furthermore characterized in that it contains 0.5 - 25 per cent by weight of ol igosaccharides.
  • ol igosaccharides comprise hydrocarbons having 2 - 10 sugar units.
  • Most ol igosaccharides are soluble in water and are decomposed therein by the body ' s own intestinal enzymes; their selectivity consists of stimulating the growth of certain populations within the microbial ecosystem in the intestine.
  • said ol igosaccharides can prevent pathogens and enterotoxins adhering to the wall of the intestine.
  • ol igosaccharides will provide a nutritive preparation which contains all essential constituents for the animals.
  • oligosaccharides which compounds are considered to be natural growth stimulants, furthermore obviates the use of synthetic growth stimulants.
  • Recent legislation in Scandinavia has banned the use of such synthetic substances in nutritive preparations for animals.
  • the aqueous nutritive preparation preferably contains 1 - 19 per cent by weight of hydroxy acetic acid, 0.5 - 5 per cent by weight of citric acid, and 0.1 - 5 per cent by weight of sorbic acid.
  • the use of other organic acids besides lactic acid has an advantageous effect on the occurrence of harmful micro-organisms in the drinking water or in wet feed.
  • the addition of hydroxy acetic acid lessens the unpleasant odour produced by the lactic acid.
  • the addition of citric acid and sorbic acid has a preserving effect on the aqueous nutritive preparation. Furthermore it has become apparent that when organic acids are added in a combination thereof the synergetic effect obtained is better than when only lactic acid and/or derivates thereof are used.
  • the nutritive preparation preferably contains 0.1 - 1.0 per cent by weight of isopropanol, 0.01 - 0.5 per cent by weight of quaternary ammonium chloride, 0.1 - 5 per cent by weight of dodecyl dimethyl ammonium chloride, 0.01 - 0.5 per cent by weight of polydimethyl siloxane.
  • the present invention furthermore relates to a method for preparing the aqueous nutritive preparation, which method is characterized in that an aqueous mixture of lactic acid, hydroxy acetic acid and sorbic acid is admixed with an aqueous mixture of citric acid, hydroxy acetic acid, isopropanol, quaternary ammonium chloride, dodecyl dimethyl ammonium chloride and polydimethyl siloxane, after which oligosaccharides and trace elements are added to the solution thus obtained. If oligosaccharides are directly added to the aqueous mixture containing lactic acid, undesirable precipitation will occur.
  • the admixing of the mixture containing lactic acid and the mixture containing citric acid is carried out at a temperature of for example 40 - 90 ° C, preferably 60 - 80 ° C.
  • the advantage of such a method is that no premature precipitation will occur.
  • the shelf 1 ife of two separate mixtures will be longer in the embodiment wherein all the components are present in one mixture.
  • the aqueous nutritive preparation thus prepared is used in drinking water or in wet feed in intensive stock farming, preferably in an amount of 0.5 - 3 litres of aqueous nutritive preparation per 1000 litres of drinking water or wet feed. If the amount of aqueous nutritive preparation is less than 0.5 litres per 1000 litres, the micro-organism- inhibiting effect will be too small, and if the amount is more than 3 litres per 1000 litres, no enhanced micro-organism-inhibiting effect will be observed.
  • the addition of the aqueous nutritive preparation according to the present invention to dry feed preferably takes place by spraying the aqueous nutritive preparation onto the dry feed. Said spraying with the aqueous nutritive preparation furthermore has a preserving effect on the dry feed.
  • the pH value of the drinking water or the wet feed after the addition of the aqueous nutritive preparation is preferably lower than 6, more preferably 3.5 - 4.5. If the pH value is higher than 6, the microorganism-inhibiting effect that is observed will be insufficient.
  • the present invention furthermore relates to the use of the aqueous nutritive preparation according to the present invention for treating hooves of animals.
  • a great many animal waste products, such as urine and manure, are present on the floor of a stable. Such harmful materials accumulate in the small openings in the hooves of animals. After some time the hoof will become inflamed, which has an adverse effect on the animal ' s well-being.
  • aqueous nutritive preparation may be applied directly to the hoof to be treated, but it is also possible to add the aqueous nutritive preparation to a bath, in which the animal to be treated is made to stand.
  • the aqueous nutritive preparation has a disinfecting effect on the hooves of animals.
  • Example 1 An aqueous solution (A) of lactic acid was prepared by dissolving 70 g of liquid lactic acid, 10 g of liquid hydroxy acetic acid and 0.3 g of powdery sorbic acid in 29.7 g of water. The solution (A) thus obtained was thoroughly stirred and a clear solution was obtained. Then 12 g of the trace elements copper, zinc, phosphorus and cobalt present in the chelate bonding were added to the clear solution. The aqueous nutritive preparation (F) thus obtained was added to the drinking water for salmonella-infected chickens in an amount of 21 per 10001 of drinking water. After 2 days the gastro-intestinal tract of said chickens appeared to be free from salmonella.
  • Example 2 An aqueous solution (A) of lactic acid was prepared by dissolving 70 g of liquid lactic acid, 10 g of liquid hydroxy acetic acid and 0.3 g of powdery sorbic acid in 29.7 g of water. The solution (A) thus obtained was thoroughly stirred and
  • oligosaccharides An amount of 10 g of oligosaccharides was added to the aqueous nutritive preparation (F) prepared in example 1 at a temperature of 70 ' C.
  • the mixture (G) thus obtained was added to drinking water for salmonella-infected chickens in the same amounts as used in example 1.
  • the use of oligosaccharides increased the uptake of the trace elements present in the chelate bonding into the gastro-intestinal tract. Further analysis of the excrements showed that the addition of oligosaccharides has resulted in an improved digestion of protein, because no undigested food remnants were found in the excrements. Comparative example 1
  • An aqueous solution (A) of lactic acid was prepared in a manner corresponding with example 1 by dissolving 70 g of liquid lactic acid. 10 g of liquid hydroxy acetic acid and 0.3 g of powdery sorbic acid in 29.7 g of water. The solution (A) thus obtained was thoroughly stirred and a clear solution was obtained.
  • Another water-containing solution (B) was prepared by adding the following compounds: 12.9 g of citric acid, 8.7 g of hydroxy acetic acid, 0.66 g of isopropanol, 0.02 g of quaternary ammonium chloride, 3.04 g of dodecyl dimethyl ammonium chloride and 0.08 g of polydimethyl siloxane to 49.2 g of water. After the above components had been added to the water while stirring, the clear solution (B) was obtained. The final aqueous nutritive preparation was obtained by combining 9 parts of solution (A) with 1 part of solution (B).
  • the solution (C) thus obtained was added to the drinking water for salmonella-infected chickens in an amount of 2 1 per 1000 1 of drinking water.
  • the drinking water was used for a period of 3 days.
  • the amount of solution (C) was reduced from 2 1 to 1 1 per 1000 1 of drinking water over a period of 4 days. After this period the gastro-intestinal tract of said chickens appeared to be free from salmonella.
  • Example 3 An amount of 5 per cent by weight of the trace elements copper, zinc, phosphorus, manganese, magnesium, iodine, selenium and cobalt in a chelate bonding was added to the aqueous nutritive preparation (D) of comparative example 2. The addition of these special trace elements resulted in a balanced nutritive preparation (E) for chickens. In addition, after a period of 2 - 3 days the salmonella-infected chickens were free from salmonella bacteria. The preparation was used in the amounts stated in example 1. When the aforesaid trace elements were not used in chelate form, it took as long as 7 days before the salmonella-infected chickens were declared free from salmonella. Comparative example 3
  • the aqueous nutritive preparation of example 1 was added in an amount of 1.5 1 per 1000 1 of water.
  • the composition thus obtained was transferred to a so-called walk-in trough for stables.
  • the cows were led through this walk-in trough every day upon entering and leaving the stable.
  • the number of inflammations of the hooves decreased considerably in comparison with a control group of cows that were not treated with the aqueous nutritive preparation of example 1.

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention se rapporte à une préparation nutritive aqueuse composée sensiblement à partir d'une base d'acide lactique et/ou de dérivés d'un tel acide, d'un ou de plusieurs acides organiques et d'oligo-éléments, lesdits oligo-éléments qui sont sélectionnés dans le groupe constitué par le cuivre, le zinc, le phosphore, le manganèse, le magnésium, l'iode, le sélénium et le cobalt, étant présents dans un liant chélaté en quantité représentant de 0,01 à 25 % du poids dudit liant. L'invention se rapporte en outre à des procédés de préparation d'une telle composition nutritive, à l'utilisation d'une telle composition dans l'eau potable ou dans une alimentation humide pour animaux, ainsi qu'à l'utilisation d'une telle composition nutritive pour traiter les sabots de certains animaux.
PCT/NL1997/000615 1996-11-11 1997-11-10 Preparation nutritive aqueuse contenant un acide lactique, un acide organique et des oligo-elements chelates WO1998020749A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU49699/97A AU4969997A (en) 1996-11-11 1997-11-10 Aqueous nutritive preparation comprising lactic acid, organic acid and chelated trace elements

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1004488 1996-11-11
NL1004488A NL1004488C2 (nl) 1996-11-11 1996-11-11 Waterig voedingsmiddel hoofdzakelijk op basis van een zuur en/of derivaten hiervan.

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Publication Number Publication Date
WO1998020749A1 true WO1998020749A1 (fr) 1998-05-22

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PCT/NL1997/000615 WO1998020749A1 (fr) 1996-11-11 1997-11-10 Preparation nutritive aqueuse contenant un acide lactique, un acide organique et des oligo-elements chelates

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AU (1) AU4969997A (fr)
NL (1) NL1004488C2 (fr)
WO (1) WO1998020749A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048382A1 (fr) * 1998-03-24 1999-09-30 Stichting Dienst Landbouwkundig Onderzoek Conservation par des alcools superieurs
WO1999051218A1 (fr) * 1998-04-03 1999-10-14 Verdugt B.V. Compositions biocides comprenant de l'acide lactique et au moins un autre acide tel que l'acide formique, l'acide acetique et l'acide propionique
EP1205115A3 (fr) * 2000-11-09 2002-07-03 Nutrinova Nutrition Specialties & Food Ingredients GmbH Usage d'une préparation acide comme additif alimentaire dans l'élevage d'animaux de ferme
NL1017252C2 (nl) * 2001-01-31 2002-08-01 A K B Beheermij B V Waterige samenstelling voor toepassing bij dieren.
EP1228699A1 (fr) * 2001-02-02 2002-08-07 Nutrinova Nutrition Specialties & Food Ingredients GmbH Préparation contenant de l'acide sorbique comme additif alimentaire destiné à l'élevage d'animaux
EP1228698A1 (fr) * 2001-02-02 2002-08-07 Nutrinova Nutrition Specialties & Food Ingredients GmbH Acide sorbique comme additif alimentaire stabilisant la croissance dans l'élevage d'animaux
WO2004110425A1 (fr) * 2003-06-12 2004-12-23 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Utilisation d'acide sorbique pour empecher des infections bacteriennes et augmenter les performances chez des animaux
EP2724724A1 (fr) 2012-10-26 2014-04-30 Intracare B.V. Traitement et prévention des infections épithéliales par des chélates de zinc et de cuivre
CN107311290A (zh) * 2017-08-17 2017-11-03 付全贵 一种富微量元素饮用水的制备工艺
US10166212B2 (en) * 2015-06-17 2019-01-01 Dantrace-Danfeed Ivs Oral use of zinc and copper gluconates in the treatment of digital dermatitis

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034692A1 (en) * 1970-07-13 1972-01-27 Molkerei J.A. Meggle, 8094 Reit mehnng Trace element concentrates - in liquid whey for animal food
FR2102939A5 (en) * 1970-08-31 1972-04-07 Charbonnages Ste Chimique Additives for animal foodstuffs - added as a stable conc aq soln
WO1981002242A1 (fr) * 1980-02-11 1981-08-20 Hansens Lab Composition riche en elements
EP0154959A2 (fr) * 1984-03-14 1985-09-18 DOX-AL ITALIA S.p.A. Nourriture liquide complète et intégrée pour bétail
EP0486961A2 (fr) * 1990-11-20 1992-05-27 Firma Hjorth Petersen Procédé de préparation d'un concentré contenant des oligoéléments approprié pour l'homme et les animaux
US5229118A (en) * 1991-09-30 1993-07-20 Aqua-10 Corporation Feed and water additive and method of making same
WO1996024248A1 (fr) * 1995-02-06 1996-08-15 Kemira Chemicals Oy Composition microbicide et ses emplois

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GB1048724A (en) * 1964-03-06 1966-11-16 Feed Serv Livestock Feeds for ruminants
JPS53111010A (en) * 1977-03-10 1978-09-28 Ueno Seiyaku Oyo Kenkyujo Kk Stable sorbinic acid suspension comosition process for preparing same and method of preserving food and drink and feed using same
DE2731877A1 (de) * 1977-07-14 1979-02-01 Rudolf Schanze Verfahren zur herstellung von ammoniumlactat enthaltenden mischungen aus waessrigen milchverarbeitungsrueckstaenden
US4247561A (en) * 1979-04-16 1981-01-27 Nelson R W Process and method of use for a stable emulsified edible liquid starch product
JPH07228533A (ja) * 1994-02-17 1995-08-29 Jun Kimura 動物用ドリンク剤
DE29521537U1 (de) * 1994-09-19 1998-04-30 Hoechst Ag, 65929 Frankfurt Flüssige und breiige Futtermittel aus Kartoffeln, Lebensmittelresten, Preßtreber, Bierhefe, Destillationsschlempe und ähnlichen Bestandteilen

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034692A1 (en) * 1970-07-13 1972-01-27 Molkerei J.A. Meggle, 8094 Reit mehnng Trace element concentrates - in liquid whey for animal food
FR2102939A5 (en) * 1970-08-31 1972-04-07 Charbonnages Ste Chimique Additives for animal foodstuffs - added as a stable conc aq soln
WO1981002242A1 (fr) * 1980-02-11 1981-08-20 Hansens Lab Composition riche en elements
EP0154959A2 (fr) * 1984-03-14 1985-09-18 DOX-AL ITALIA S.p.A. Nourriture liquide complète et intégrée pour bétail
EP0486961A2 (fr) * 1990-11-20 1992-05-27 Firma Hjorth Petersen Procédé de préparation d'un concentré contenant des oligoéléments approprié pour l'homme et les animaux
US5229118A (en) * 1991-09-30 1993-07-20 Aqua-10 Corporation Feed and water additive and method of making same
WO1996024248A1 (fr) * 1995-02-06 1996-08-15 Kemira Chemicals Oy Composition microbicide et ses emplois

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048382A1 (fr) * 1998-03-24 1999-09-30 Stichting Dienst Landbouwkundig Onderzoek Conservation par des alcools superieurs
WO1999051218A1 (fr) * 1998-04-03 1999-10-14 Verdugt B.V. Compositions biocides comprenant de l'acide lactique et au moins un autre acide tel que l'acide formique, l'acide acetique et l'acide propionique
EP1205115A3 (fr) * 2000-11-09 2002-07-03 Nutrinova Nutrition Specialties & Food Ingredients GmbH Usage d'une préparation acide comme additif alimentaire dans l'élevage d'animaux de ferme
US6787166B2 (en) 2000-11-09 2004-09-07 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Use of an acid preparation as feed additive in farm animal husbandry
WO2002060433A1 (fr) * 2001-01-31 2002-08-08 A.K.B. Beheermaatschappij B.V. Solution aqueuse de chelates de cuivre et de zinc utilisee pour traiter les animaux
NL1017252C2 (nl) * 2001-01-31 2002-08-01 A K B Beheermij B V Waterige samenstelling voor toepassing bij dieren.
EP1228698A1 (fr) * 2001-02-02 2002-08-07 Nutrinova Nutrition Specialties & Food Ingredients GmbH Acide sorbique comme additif alimentaire stabilisant la croissance dans l'élevage d'animaux
EP1228699A1 (fr) * 2001-02-02 2002-08-07 Nutrinova Nutrition Specialties & Food Ingredients GmbH Préparation contenant de l'acide sorbique comme additif alimentaire destiné à l'élevage d'animaux
WO2004110425A1 (fr) * 2003-06-12 2004-12-23 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Utilisation d'acide sorbique pour empecher des infections bacteriennes et augmenter les performances chez des animaux
EP2724724A1 (fr) 2012-10-26 2014-04-30 Intracare B.V. Traitement et prévention des infections épithéliales par des chélates de zinc et de cuivre
US10166212B2 (en) * 2015-06-17 2019-01-01 Dantrace-Danfeed Ivs Oral use of zinc and copper gluconates in the treatment of digital dermatitis
CN107311290A (zh) * 2017-08-17 2017-11-03 付全贵 一种富微量元素饮用水的制备工艺
CN107311290B (zh) * 2017-08-17 2020-11-06 付全贵 一种富微量元素饮用水的制备工艺

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Publication number Publication date
NL1004488C2 (nl) 1998-05-14
AU4969997A (en) 1998-06-03

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