+

WO1998010817A1 - Dispositif d'inhalation - Google Patents

Dispositif d'inhalation Download PDF

Info

Publication number
WO1998010817A1
WO1998010817A1 PCT/EP1997/004768 EP9704768W WO9810817A1 WO 1998010817 A1 WO1998010817 A1 WO 1998010817A1 EP 9704768 W EP9704768 W EP 9704768W WO 9810817 A1 WO9810817 A1 WO 9810817A1
Authority
WO
WIPO (PCT)
Prior art keywords
suction
section
head piece
wall
suction channel
Prior art date
Application number
PCT/EP1997/004768
Other languages
German (de)
English (en)
Inventor
Alfred Von Schuckmann
Original Assignee
Alfred Von Schuckmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfred Von Schuckmann filed Critical Alfred Von Schuckmann
Priority to AU43821/97A priority Critical patent/AU4382197A/en
Publication of WO1998010817A1 publication Critical patent/WO1998010817A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Definitions

  • the invention relates to a device for
  • Packaging chamber containing 00014 is there in the form of a
  • 00035 matching negative form of a valve having a dome 00036 ⁇ itzflache has a strong tendency to close the coupled end zone there of the capsule.
  • the rotary drum is designed to be transparent, so 00040 that the user can see through the capsule, which is also necessarily transparent, to determine whether 00042 there is still powder inside, so that he, ie 00043 specially designed to continue the suction until it is completely emptied. All of this can lead to panic-like handling and is therefore particularly problematic for older people.
  • 00047 00048 Subject of an older, not previously published 00049 patent application by the applicant is to open the bowl of a blister pack containing 00050 powdery substance over 00051 a pestle acting as a proboscis.
  • 00052 the latter perforates the cover plate 00053 which closes the bowl.
  • the free-stretched section of the cover film is pressed 00054 into the bowl cavity. This can lead to a shadow zone in which, although 00056 minimal parts of the filling can remain unmoved.
  • 00057 00058 GB-2 142 246 A proposes to pierce a single 00060 blister pack that has only one packaging chamber 00059 through a device-side mandrel 00061 in such a way that both the cover film and 00062 the wall section of the plate body forming the bowl forming part of the plate together be perforated so that the pulverför00064 mige substance gets into an intermediate chamber of the inhaler Vor00065 direction, from which it is transported away via the suction air stream 00066.
  • the object of the present invention is to design a device according to the gat00069, while maintaining a fracturing-free manner of opening so that the 00071 distal end of the suction mouthpiece an unrestricted
  • 00080 kungskamer is more accessible. In place
  • 00083 knife can be parked in the direction of the suction channel
  • 00088 complete clearing instead. That can be done with a
  • the parts forming the head piece can be
  • the foot part is the cover plate of a storage container.
  • the headpiece has at least one air inlet duct
  • the two or more air intake ducts are mouth-open
  • the powdery substance is finely divided.
  • Fig. 1 shows the device according to the invention in front
  • 00175 size, 00176 Fig. 2 shows the device with the reservoir open
  • Fig. 3 is a top view of this
  • FIG. 5 is a top view of this
  • FIG. 7 is a top view of this
  • FIG. 8 shows a side view corresponding to FIG. 4,
  • FIG. 9 is a top view of this
  • 00196 Fig. 10 is a vertical section through the upper region
  • FIG. 11 shows the section along line XI-XI in FIG. 10,
  • 00202 Fig. 12 is a vertical section through the upper region
  • the inhaler device V shown is realized as a long, box-shaped housing. Its volume portion, which weighs more than 00231, provides a storage container 1. 00232, which passes via a foot part 2 into a head piece 3, which forms a dispenser mechanism. 00234 00235 The foot section 2 also forms a cover plate as a 00236 partition to the rotating tower-like head piece 3. 00237 The rotation takes place around a geometrical vertical 00238 axis xx (see Figure 10). It lies in the center 00239 of the square cross section of the elongated device V 00241 00242.
  • the storage container 1 of the device V accommodates a multiplicity of individual packaging chambers 4. The powdery substance 5 contained.
  • 00245 borrowed in Figure 14 in the form of a dot matrix.
  • 00246 Chamber 4 is only partially filled.
  • the pulvri00247 gene substance 5 it can be medicament powder 00248, which is brought to the destination by suction through a mouthpiece 6 00249 of the device V.
  • Said 00250 th mouthpiece 6 sits eccentrically and free-standing 00251 arranged on the 00252 head piece 3 connected to the storage container 1.
  • the packaging chambers 4 are realized as a single blister pack 00255. They have a chamber-forming bowl 7. 00256 It is deep-drawn on a flange-retaining plate body 8 00257.
  • the opening 9 of the pot-shaped bowl 7, which points downward in FIG. 14, is overlaid with a thin 00259 cover film 10.
  • the latter is laminated on 00260.
  • 00261 hat-shaped profile of the packaging chamber 4.
  • the 00262 hat edge continues into a radially aligned, elongated, flag-like projection 11, which 00264 is designed with 00265 with a better grip by transverse ribs 12.
  • the socket 11 is about fingerkuppen00266 in size.
  • the cover film 10 is of congruent shape with respect to the plate body 8 00269. For example, it consists of 00270 aluminum foil.
  • transparent elastic plastic material 00272 is used with the premise that the contents protecting, ring-closed packaging chamber 4 in the wall section of its bowl 7 can be opened by cutting 00275. This takes place in device V, namely 00276 via a cutting device S inside the head piece 00277 kes 3. 00279 The cut is made while rotating it.
  • 00288 13 dips into a pre-cutter, a wall entrance a
  • caliber axis x-x inner cutting edge carries that
  • 00379 divides into two flow inlets 26, opening at far outer sides of the wall of 00381, which are spaced far apart from one another by 00380. They unite in a connection 00382 27. It is located just above a compartment 28 located at the foot part 3 or the cover plate 3 for correct position 00384 Admission of the packaging chamber 4. In the area of the compartment
  • Said additional air 00419 flow openings 31 extend perpendicular to the course 00420 of the suction channel 14 in the area of the mouthpiece 6. They 00421 form a type of cross channel with a high degree of mixing effect 00422 in this channel section of the inhaler. For this purpose, 00423 results in a secondary air flow 00424 L 'via the air flow openings 31. 00425 00426 Knife 13, suction channel 14 and mounting caterpillar 19 are molded on the 00427 rotatable head piece 3, whereby the compartment 28 00428 is also taken into account.
  • the head piece 3 and foot section 2 form part of the compartment 28 00429, realized by a counter bend 00431 mating to the bend 00430 of the core section 24.
  • 00432 00433 The compartment 28 also appears as a radially oriented 00434 insert cross-section, which takes into account the hat-shaped silhouette of the packaging chamber 4 or 00436 blister pack in cross-section.
  • the insert 00437 cross-section therefore comprises an essentially rectangular portal 32, formed by proportionate recesses in the 00439 wall of the head piece 3 and that of the foot part 2. Below this and realized in the foot part 2 there is a 00441 base of the portal 32 or the compartment 28 widening , 00442 bottom-side free space 33.
  • the inner end of the compartment 28 is essentially 00448 rounded according to the circular cross-sectional contour of the 00449 bowl 7; the same applies with regard to the 00450 area of the free space 33 there, which is adapted to the curvature 00451 of the plate body and cover film edge 8 'and 10' 00452.
  • 00453 00454 The physical axis of rotation of the head piece 3 is reached by 00455 a central journal 34.
  • the axle pin 00456 34 extends integrally from the head piece 3 and ends in a 00457 locking head 35. Its horizontal locking flanks underneath 00458 fen an annular shoulder 36 of a bearing bore in the deck 00459 plate or the foot part 2.
  • the locking is begün00460 increased by an axial slot 37.
  • 00461 00462 A concentric guide in the peripheral area of the 00463 head piece 3 then results from a 00465 ring wall 38 which starts from the 00464 foot part 2 and points away from the storage container 1. This is in a suitable guide groove 00466 39. The latter is open at the bottom near the edge of the head 00467 piece 3 educated.
  • ring wall 38 and 00468 guide groove 39 are interrupted in the area of the compartment 28. 00469 Both parts also act as swing gates.
  • 00470 00471 A trench 40 extending over a good 00472 180 ° extends from the top of the foot part 2.
  • the 00473 extends concentrically to axis xx.
  • 00474 protrudes from the underside of the head piece 3 00475 of the pin 41.
  • the pin 41 in suction position the pin 41, on the other hand, kicks against the end limit stop 424 (cf. FIG. 13).
  • the wall of the head piece 3 closes the 00483 section or portal-forming section of the ring wall 38 00484 in the manner of a rotating gate.
  • the ring wall 38 is a 00485 closing element rotating gate-like in front of the portal or 00486 compartment-forming section of the rotating head 3.
  • 00487 00488 Remains to be noted that the reservoir 1
  • the packaging chamber 4 is key
  • the compartment 28 only needs to be opened again to 00524, which is done by turning the head piece 3 back to the 00525 exactly stop-defined loading position.
  • 00526 00527
  • the entrance to the free space 00528 has a steerable ramp 47 (FIG. 19).
  • 00529 00530
  • a head piece 3 00531 with the square outline and the subsequent, same outline shape 00532 foot part 2 overlapping protective cap 48 extends sufficiently with a suitable inner contour the rotary joint 00534 49 between the two parts and thus acts to prevent rotation.
  • 00535 The edge of the protective cap steps against a shoulder 00536 50 of the storage container 1.
  • the protective cap 48 00537 is held in a frictionally locking manner. Not fully inserted, 00538 it can be used as a "polygon key", for example, by care personnel 00539 nal. Contamination of the head part 00540 3, in particular of the mouthpiece 6, can thus be excluded by the patient 00541. 00542 00543 All disclosed features are essential to the invention.
  • the disclosure of the application the disclosure content of the associated / attached priority documents (copy of the prior application) is hereby fully included, also for the purpose of including features of these 00548 documents in claims of the present application with 00549. 00550

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention concerne un dispositif (V) permettant de prélever par aspiration des substances pulvérulentes (5) contenues dans des chambres fermées circulaires (4) à section de paroi pouvant s'ouvrir, au moyen d'une lame (13) se déplaçant approximativement en forme de sécante par rapport à la paroi de chambre. Au voisinage de cette lame se trouve un canal d'aspiration (14) aboutissant dans un embout d'aspiration (6), l'écoulement de l'air aspiré dans ce canal entraînant la substance pulvérulente (5). Dans le but de permettre un prélèvement complet de la substance pulvérulente, la lame (13) libère par découpage une section de surface de paroi (15) reliée par une charnière pouvant être rompue en direction du canal d'aspiration (14), cette section de surface de paroi étant soumise à un courant de fond par le courant d'air aspiré (L) dévié dans la chambre (4).
PCT/EP1997/004768 1996-09-12 1997-09-02 Dispositif d'inhalation WO1998010817A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU43821/97A AU4382197A (en) 1996-09-12 1997-09-02 Inhaler device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19637125.2 1996-09-12
DE1996137125 DE19637125A1 (de) 1996-09-12 1996-09-12 Inhalier-Vorrichtung

Publications (1)

Publication Number Publication Date
WO1998010817A1 true WO1998010817A1 (fr) 1998-03-19

Family

ID=7805406

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1997/004768 WO1998010817A1 (fr) 1996-09-12 1997-09-02 Dispositif d'inhalation

Country Status (3)

Country Link
AU (1) AU4382197A (fr)
DE (1) DE19637125A1 (fr)
WO (1) WO1998010817A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN188288B (fr) * 1996-10-01 2002-08-31 Cipla Ltd
ATE390944T1 (de) * 1999-07-23 2008-04-15 Mannkind Corp Einzelportionskapseln für einen trockenpulverinhalator
ITMO20020297A1 (it) * 2002-10-16 2004-04-17 Roberto Oliva Inalatore per preparati monodose in capsule.
DE102006010089A1 (de) 2006-02-24 2007-10-18 Aha-Kunststofftechnik Gmbh Trockenpulver-Inhalator
DE102007040366A1 (de) 2007-08-17 2009-02-19 Aha Kunststofftechnik Gmbh Trockenpulver-Inhalator
WO2013016784A1 (fr) 2011-08-04 2013-02-07 Victor Esteve Inhalateur de poudre sèche
CN104582772B (zh) * 2012-07-05 2018-02-09 葛兰素集团有限公司 吸入器装置
EP3021919B1 (fr) 2013-07-16 2017-10-04 Emphasys Importadora, Exportadora E Distribuidora De Embalagens Ltda. Inhalateur à poudre sèche

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117844A (en) * 1976-02-11 1978-10-03 Allen & Hanburys Limited Device for dispensing medicaments
GB2142246A (en) 1983-05-24 1985-01-16 Glaxo Group Ltd Medical administration devices
DE4118674A1 (de) * 1990-06-08 1991-12-12 Glaxo Group Ltd Medikamentenaufnahmebehaelter und ausgabevorrichtung
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
EP0666085A1 (fr) 1994-02-02 1995-08-09 Plurichemie Anstalt Appareil et méthode pour inhaler des médicaments
WO1996009085A1 (fr) * 1994-09-21 1996-03-28 Inhale Therapeutic Systems Appareils et procedes de dispersion de medicaments pulverulents secs

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4117844A (en) * 1976-02-11 1978-10-03 Allen & Hanburys Limited Device for dispensing medicaments
GB2142246A (en) 1983-05-24 1985-01-16 Glaxo Group Ltd Medical administration devices
DE4118674A1 (de) * 1990-06-08 1991-12-12 Glaxo Group Ltd Medikamentenaufnahmebehaelter und ausgabevorrichtung
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
EP0666085A1 (fr) 1994-02-02 1995-08-09 Plurichemie Anstalt Appareil et méthode pour inhaler des médicaments
WO1996009085A1 (fr) * 1994-09-21 1996-03-28 Inhale Therapeutic Systems Appareils et procedes de dispersion de medicaments pulverulents secs

Also Published As

Publication number Publication date
DE19637125A1 (de) 1998-03-19
AU4382197A (en) 1998-04-02

Similar Documents

Publication Publication Date Title
EP1993643B1 (fr) Inhalateur pour substances pulvérulentes
DE19704849B4 (de) Austragvorrichtung für Medien
EP2311515B1 (fr) Distributeur pour des substances sous forme de poudre contenues dans un emballage séparé
US4307734A (en) Snuff dispenser
EP0147755B1 (fr) Inhalateur
EP3099360B1 (fr) Inhalateur de poudre et set pour l'inhalation de poudre
DE68911003T2 (de) Verteiler für eine pulverförmige Medikation.
DE69607015T2 (de) Inhalationsvorrichtung zur genauen und reproduzierbaren, datierten abgabe von pulverförmigen arzneistoffen
DE69102928T2 (de) Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen.
DE3535561C2 (de) Vorrichtung zum Inhalieren einer pulverförmigen medizinischen Substanz
DE69722257T2 (de) Arzneiverabreichung und verpackung
DE2449179C3 (de) Inhalator für pulverförmige Substanzen
DE60131760T2 (de) Vorrichtung zur verabreichung von physiologisch aktiven wirkstoffen in pulverform
DE2743574A1 (de) Spender-behaelter zur einzelausgabe kleiner artikel
DE69607016T2 (de) Vorrichtung zur vor-dosierung eines pulverförmigen produkts für eine produktabgabevorrichtung
DE3609570A1 (de) Dosierverpackung
DE4340768A1 (de) Vorrichtung zum Inhalieren
DE4436051A1 (de) Vorrichtung zum Betätigen von Aerosolabgabegeräten
DE19619536A1 (de) Inhalier-Vorrichtung
DE60211945T2 (de) Medikamentenverpackungen und ausgabevorrichtung dafür
DE4118674A1 (de) Medikamentenaufnahmebehaelter und ausgabevorrichtung
WO1998010817A1 (fr) Dispositif d'inhalation
EP3374010A2 (fr) Inhalateur pouvant être actionné manuellement
DE60013799T2 (de) Pulverinhalator
DE19522415C2 (de) Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH KE LS MW SD SZ UG ZW AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 1998513210

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: CA

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载