WO1998008561A1 - Nouvelle aiguille pour produits injectables - Google Patents
Nouvelle aiguille pour produits injectables Download PDFInfo
- Publication number
- WO1998008561A1 WO1998008561A1 PCT/ES1997/000217 ES9700217W WO9808561A1 WO 1998008561 A1 WO1998008561 A1 WO 1998008561A1 ES 9700217 W ES9700217 W ES 9700217W WO 9808561 A1 WO9808561 A1 WO 9808561A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- filter
- new needle
- patient
- injectables
- needle
- Prior art date
Links
- 239000007788 liquid Substances 0.000 claims abstract description 7
- 230000002787 reinforcement Effects 0.000 claims abstract 2
- 239000000463 material Substances 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 9
- 239000004753 textile Substances 0.000 claims description 5
- 230000017531 blood circulation Effects 0.000 claims description 2
- 230000000717 retained effect Effects 0.000 claims description 2
- 239000007787 solid Substances 0.000 claims description 2
- 239000000047 product Substances 0.000 claims 2
- 239000012263 liquid product Substances 0.000 claims 1
- 239000007769 metal material Substances 0.000 claims 1
- 230000008878 coupling Effects 0.000 abstract description 4
- 238000010168 coupling process Methods 0.000 abstract description 4
- 238000005859 coupling reaction Methods 0.000 abstract description 4
- 229920000742 Cotton Polymers 0.000 abstract description 2
- 238000007599 discharging Methods 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 12
- 229940079593 drug Drugs 0.000 description 11
- 239000000825 pharmaceutical preparation Substances 0.000 description 6
- 238000011109 contamination Methods 0.000 description 5
- 229940126534 drug product Drugs 0.000 description 5
- 230000006978 adaptation Effects 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000002483 medication Methods 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000004806 packaging method and process Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000002657 fibrous material Substances 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 238000012858 packaging process Methods 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3145—Filters incorporated in syringes
Definitions
- the present specification refers to a new needle for injectables, whose obvious purpose is to be configured as a needle capable of being used as a link for the introduction of a pharmaceutical product or similar, into the body of a patient, regardless of whether this needle be used as an element that vehicles the introduction of the drug parenterally or intravenously, having in the internal area a filter element, which can be of any nature, including textile, paper, etc., of a sterile nature, according to the which is achieved that the drug product that is introduced into the body of the patient, does not present any particle derived from any previous action on the container or container container of the product, such as a particle corresponding to the container that at the time of its opening can be introduced inside the container itself, according to the implosion generated by the breakage of the neck of the to blister or similar.
- a filter element which can be of any nature, including textile, paper, etc., of a sterile nature
- This invention has its application within the industry dedicated to the manufacture of apparatus, elements and accessories for medicine and surgery, especially within the industry dedicated to the manufacture of needles for injectables.
- Galenic is the pharmacy subject that is responsible, among other things, for providing adequate regulations for the preparation of drugs and their relevant packaging, so that the drugs retain their purity to the fullest.
- the Pharmacopoeia is the art of preparing medicines, and is configured as an official book, which is written and periodically reviewed by a scientific commission, published by each State to serve as a legal norm in the preparation, testing, dispensing, etc. of medications.
- the mechanism of this contamination can be produced by the fact that the ampoules are filled in a vacuum, and it can be deduced that the fracture of the material by its throttling or pre-cutting line, can generate an implosion under the aforementioned vacuum that ultimately produces the introduction of microparticles inside the container itself or blister.
- Another possible contamination can occur, according to some specialists, by the attack suffered by the glass by the water under a reaction between both products .
- the new needle for injectables that invented it tion proposes constitutes by itself an evident novelty within its field of application, since in view of its use, physical contamination that may exist due to deposits or crystallizations incorporated in the vials destined to be, is totally and taxatively ignored.
- the new needle for injectables object of the invention is constituted from a substantially elongated body, which at one of its ends has a bevel cut, this body being configured as a cylindrical element made of stainless steel, disposing at the opposite end of the corresponding conventional body for coupling to a syringe or similar element, through which the evacuation of its contents is carried out towards the patient, presenting in the internal area of the pavilion or fixing link on the adaptation body with the syringe or the like, a filter made of textile material or the like, according to which the constituent liquid of the drug product passes through the filter in question, the possible particles that may be deposited in the drug product being retained in the filter itself . In this way, it is avoided that small particles, can pass through the internal channel of the needle itself, being introduced into the patient's body.
- the filter incorporated in the pavilion made of any material that is considered appropriate, prevents the blood that can be extracted to the patient at the time of applying the needle, passes inside the syringe or extreme area thereof , being able to generate a thrombus.
- Figure number 1 It shows a side elevation view of the new needle for injectables object of the invention, inside which, specifically inside the pavilion, a filter has been incorporated.
- Figure number 2.- Shows a view of the object represented in figure number 1, in which the relevant sectioning of the area of the pavilion in which the filter in question is incorporated has been made.
- the new needle for injectables (1) is constituted from an internally hollow cylindrical body (2), which has a bevelled end, designed to facilitate the introduction of the body (2) onto the patient, presenting at the opposite end an adaptation body (3) to the mouthpiece of a syringe or terminal of an apparatus of identical application, having inside this adaptation body (3) a mouthpiece (4) reinforced twice perimetrically, which has a central hole for access to a hall (5), in the interior of which and as represented in figure number 2, a filter (6) of any nature that is considered opportune is incorporated, allowing the filter (6) to evacuate the medicated product into the patient's body in a state liquid, but at the same time preventing the possible deposits of solid matter in suspension in the constituent liquid of the drug product, from entering the patient's body through the perforation n existing in the internal area of the body (2).
- the filter (6) at the same time prevents the introduction of the area (2) in the patient's body, the blood flow exceeds the filter in question (6) , preventing the possibility of a thrombus forming at the time of pumping by injection of the drug product.
- the filter (6) will preferably be made of branch cotton, properly compacted or a vegetable fiber material, or a textile fiber, which, when properly coupled at the indicated site, will allow the liquid to enter the body. human, taxatively preventing the passage of any material in suspension in it. It should also be noted that obviously the constituent material of the filter (6) proper, will be properly aseptized.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Nouvelle aiguille pour produits injectables, consistant en l'accouplement à l'intérieur du pavillon (5) de l'aiguille (1), d'un filtre (6) fabriqué de préférence en coton dûment compacté et aseptisé, le filtre étant incorporé dans le pavillon (5) et faisant face à la zone d'accouplement de l'extrémité d'une seringue ou d'un dispositif similaire pour l'évacuation d'un produit médicamenteux à l'état liquide, le pavillon (5) étant doté de renforcements périmétriques (4) situés en parallèle.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9601872 | 1996-08-29 | ||
| ESP9601872 | 1996-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO1998008561A1 true WO1998008561A1 (fr) | 1998-03-05 |
Family
ID=8295930
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/ES1997/000217 WO1998008561A1 (fr) | 1996-08-29 | 1997-08-28 | Nouvelle aiguille pour produits injectables |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO1998008561A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005113038A3 (fr) * | 2004-05-10 | 2006-09-28 | Bracco Diagnostics Inc | Seringue au capuchon et à raccord luer améliorés |
| WO2018051312A1 (fr) * | 2016-09-19 | 2018-03-22 | Lupin Limited | Filtre en ligne pour administration de médicament protéique/peptidique |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1490616A (fr) * | 1966-06-20 | 1967-08-04 | Nouveau système de nécessaire pour perfusion et transfusion | |
| US3757780A (en) * | 1971-02-25 | 1973-09-11 | Ishikawa Susakusho Kk | Needle assembly with longitudinally movable filter |
| US4043335A (en) * | 1975-08-23 | 1977-08-23 | Soji Ishikawa | Needle holder device of medical administrating injector |
| US4316462A (en) * | 1980-05-21 | 1982-02-23 | Siloam, Inc. | Filtering device for an injection device |
| US4435176A (en) * | 1981-10-22 | 1984-03-06 | Soji Ishikawa | Needle assembly |
| WO1987006845A1 (fr) * | 1986-05-06 | 1987-11-19 | Microgon, Inc. | Organe de filtre destine a etre utilise avec une seringue et une aiguille |
| US4743243A (en) * | 1984-01-03 | 1988-05-10 | Vaillancourt Vincent L | Needle with vent filter assembly |
| US5064418A (en) * | 1986-05-06 | 1991-11-12 | Microgon, Inc. | Filter means for use with syringe and needle |
| WO1992000039A1 (fr) * | 1990-06-29 | 1992-01-09 | Nils Stormby | Procede et instrument pour l'examen cytologique des liquides organiques et des echantillons preleves par aspiration a l'aide d'une aiguille fine |
-
1997
- 1997-08-28 WO PCT/ES1997/000217 patent/WO1998008561A1/fr active Application Filing
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1490616A (fr) * | 1966-06-20 | 1967-08-04 | Nouveau système de nécessaire pour perfusion et transfusion | |
| US3757780A (en) * | 1971-02-25 | 1973-09-11 | Ishikawa Susakusho Kk | Needle assembly with longitudinally movable filter |
| US4043335A (en) * | 1975-08-23 | 1977-08-23 | Soji Ishikawa | Needle holder device of medical administrating injector |
| US4316462A (en) * | 1980-05-21 | 1982-02-23 | Siloam, Inc. | Filtering device for an injection device |
| US4435176A (en) * | 1981-10-22 | 1984-03-06 | Soji Ishikawa | Needle assembly |
| US4743243A (en) * | 1984-01-03 | 1988-05-10 | Vaillancourt Vincent L | Needle with vent filter assembly |
| WO1987006845A1 (fr) * | 1986-05-06 | 1987-11-19 | Microgon, Inc. | Organe de filtre destine a etre utilise avec une seringue et une aiguille |
| US5064418A (en) * | 1986-05-06 | 1991-11-12 | Microgon, Inc. | Filter means for use with syringe and needle |
| WO1992000039A1 (fr) * | 1990-06-29 | 1992-01-09 | Nils Stormby | Procede et instrument pour l'examen cytologique des liquides organiques et des echantillons preleves par aspiration a l'aide d'une aiguille fine |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005113038A3 (fr) * | 2004-05-10 | 2006-09-28 | Bracco Diagnostics Inc | Seringue au capuchon et à raccord luer améliorés |
| WO2018051312A1 (fr) * | 2016-09-19 | 2018-03-22 | Lupin Limited | Filtre en ligne pour administration de médicament protéique/peptidique |
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