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WO1998005379A1 - Appareil et procede de guerison et d'amelioration du bien-etre du corps humain - Google Patents

Appareil et procede de guerison et d'amelioration du bien-etre du corps humain Download PDF

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Publication number
WO1998005379A1
WO1998005379A1 PCT/US1997/014663 US9714663W WO9805379A1 WO 1998005379 A1 WO1998005379 A1 WO 1998005379A1 US 9714663 W US9714663 W US 9714663W WO 9805379 A1 WO9805379 A1 WO 9805379A1
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WO
WIPO (PCT)
Prior art keywords
human body
bursts
stimulating
heartbeat
circuitry
Prior art date
Application number
PCT/US1997/014663
Other languages
English (en)
Inventor
Ones C. Chou
Original Assignee
Chou Ones C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chou Ones C filed Critical Chou Ones C
Publication of WO1998005379A1 publication Critical patent/WO1998005379A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells

Definitions

  • This invention relates to methods and apparatus for improving the well-being of a human body. Such methods and apparatus are particularly useful in reducing the pain and discomfort of various human ailments such as headaches, arthritis, rheumatism, back pain and drug and alcohol withdrawal symptoms.
  • a method which is similar to electrically-stimulated acupuncture is a technique which is known as transcutaneous electrical nerve stimulation. This technique reduces the discomfort of chronic pain by sending an electrical current up the spinal cord. This stimulates the brain to send pain-inhibiting impulses back down the spine.
  • Transcutaneous electrical nerve stimulator apparatus is presently used at many hospitals.
  • the efficiency and effectiveness of body stimulation methods can be improved by taking into account the natural rhythm of the human heart.
  • the heart controls the flow of blood to and from the various parts of the human body
  • the various body parts and functions are naturally tuned into the cyclic pulsations of the heart
  • the efficiency of body stimulation methods can be improved by causing the stimulation to be applied in a cyclic manner in step with the beating of the human heart.
  • the present invention comprises the steps of stimulating a human body with reoccur ⁇ ng bursts of energy, sensing the heartbeat of the human body and synchronizing the stimulation with the heartbeat by causing the energy bursts to occur at the same rate as the heartbeat
  • FIG. 1 shows in a schematic manner representative apparatus constructed in accordance with the present invention for improving the well-being of a human body
  • FIG. 2 shows a representative form of construction for the time delay circuitry of FIG. 1 ;
  • FIG. 3 shows a representative form of construction for the time duration circuitry and some of the stimulating mechanism circuitry of FIG. 1;
  • FIG. 4 is a portion of an electrocardiogram showing the various phases of a normal heartbeat cycle;
  • FIG. 5 is a timing diagram showing some of the signal waveforms occurring during the operation of the time duration circuitry of FIG. 3.
  • FIG. 1 there is shown a representative embodiment of apparatus constructed in accordance with the present invention for improving the well-being of a human body.
  • This apparatus includes a stimulating mechanism for stimulating a living human body 10 with reoccurring bursts of energy.
  • FIG. 1 shows four different types of stimulating mechanisms, any one of which may be used to provide the stimulation for the human body 10.
  • the first of these alternative stimulating mechanisms is an acoustical or sound generator 1 1 for producing bursts of acoustical energy within the hearing range of the human body 10.
  • This acoustical generator or sound generator 1 1 includes an audio signal amplifier 12 which drives a loudspeaker 13.
  • the loudspeaker 13 is positioned so that the human body 10 may hear the sound waves produced by the loudspeaker 13.
  • These sound waves take the form of sound bursts occurring within the audible range of the human ear. They may, for example, take the form of a melodious beating sound, the beats of which occur at the same rate as the heartbeat of the human 10. If desired, earphones may be used in place of the loudspeaker 13.
  • a second form of stimulating mechanism which may be used is represented b ⁇ medical treatment device 14.
  • This medical treatment device 14 may be, for example, a neurostimulator device of the type desc ⁇ bed m the above-mentioned United States Patent 4,865,048 granted to Eckerson.
  • the device 14 would include a pair of electrodes located at the two ends of a headband which is adapted to hold the electrodes against the mastoid bone structures on the two sides of the head.
  • the electrical current supplied to the electrodes would be in the form of reoccurring bursts of electrical current occurring at the same rate as the heartbeat of the human patient 10.
  • neurostimulation is useful for relieving the pain and discomfort associated with drug and alcohol withdrawal treatment
  • the present invention wherein the stimulation is synchronized with the heartbeat. improves the effectiveness of the treatment.
  • Another form of stimulating mechanism is represented by an acupuncture pulse generator 15, the output of which is connected to an acupuncture needle inserted into the human body 10.
  • the acupuncture pulse generator 15 is effective for delivering heartbeat synchronized bursts of electrical energy to the acupuncture needle.
  • a further form of stimulating mechanism which may be used is a transcutaneous electrical nerve stimulator 16.
  • This form of stimulating mechanism is in use in numerous hospitals and includes electrodes for sending an electrical current up the spinal cord of the human body 10.
  • this stimulating mechanism is modified to include a pulsing mechanism for pulsing the operation of the transcutaneous nerve stimulator so that the electrical current is sent up the spinal cord in the form of reoccurring bursts of current which are synchronized with the heartbeat of the human body 10.
  • An additional form of stimulating mechanism not illustrated, comprises a light generator for producing bursts of light energy within the awareness range of the human body 10. By proper selection of the wavelength and intensity of the light energy, the pulsating bursts of light energy produce a soothing effect on the human body 10
  • a further type of stimulating mechanism which may be used comprises a touch pressure or body pressure mechanism for applying a mild soothing pressure to the human body in a reoccurring manner m step with the human heartbeat.
  • the pressure may be. for example, in the form of a pat on the back, with the pats occurring at the same rate as the heartbeat.
  • the output of the time duration circuitry is plugged into the input of the desired stimulating mechanism and, at the same time, the output of such stimulating mechanism is plugged into the connector for a cable 17 which runs to the human body 10.
  • An exception is represented by the case of the sound generator 1 1 wherein no connection is made to the cable 17. Instead, the loudspeaker 13 is posiiioned so that it is m the hea ⁇ ng range of the human body 10. In this case, the sound energy is transferred to the human body 10 in the form of radiated sound waves and no electrical connection is required.
  • the apparatus of the present invention further includes a sensing mechanism for sensing the heartbeat of the human body 10.
  • this sensing mechanism includes a heart activity sensor 18 adapted to detect the cyclic activity of the human heart and detector circuitry 20 coupled to the heart activity sensor 18 for detecting the occurrence of unique points in the heartbeat cycles.
  • the heart activity sensor 18 may include electrocardiogram (ECG) electrodes adapted to be attached to the human body 10 for sensing the electrical currents produced by the activity of the heart or it may include a stethoscope type acoustical sensor adapted to pick up the sounds of the human heart or it may include a blood pressure sensor adapted to pick up the fluctuations in the blood pressure of the human body.
  • ECG electrocardiogram
  • the detector circuitry 20 of FIG. 1 includes a voltage comparator 21 for producing a negative-going output pulse on line 22 whenever the signal level on input line 23 exceeds a predetermined threshold value as determined by the setting of a potentiometer 24.
  • a light- emitting diode (LED) 25 is connected to the output line 22 by way of a resistor 26. When lit, the LED 25 provides an indication that heartbeat signals are being detected.
  • detector circuitry 20 detects the occurrence of the R wave peaks of the ECG signal.
  • detector 20 detects the occurrence of the peaks in the heart sounds.
  • detector 20 detects the occurrence of the peaks in the blood pressure fluctuations.
  • the embodiment of FIG. 1 further includes a synchronizing mechanism coupled to the stimulating mechanism (for example, one of units 1 1, 14, 15, and 16) and to the sensing mechanism (units 18 and 20) for synchronizing the body stimulation with the heartbeat by causing the energy bursts produced by the stimulating mechanism to occur at the same rate or frequency as the human heartbeat detected by the sensing mechanism.
  • This synchronizing mechanism includes circuitry for producing reoccurring control signal bursts for controlling the activation of the stimulating mechanism, time delay circuitry 27 for determining the position of the control signal bursts relative to the detector output pulses and time duration circuitry 28 for determining the time duration of the control signal bursts.
  • each input pulse on line 30 triggers the multivibrator (MV) 31 to cause it to produce a positive-going output pulse on its output line 32
  • MV multivibrator
  • the duration of each output pulse on line 32 is determined by the resistance value of an adjustable resistor 33 and the capacitance value of a capacitor 34 which are connected to the time constant inputs of the multivibrator 31. In the present example, this time constant value is selected to provide an output pulse duration of approximately 0.775 seconds
  • the MV pulses on the output line 32 are supplied to a first input of an AND gate 35. Supplied to the second input of the AND gate 35 are the pulses produced by a 20 Hertz oscillator 36. The pe ⁇ od of these oscillator pulses is 50 milliseconds. For the duration of each MV pulse on line 32, the AND gate 35 is enabled to pass
  • each MV output pulse on line 32 is selected so that 16 oscillator pulses are supplied to the counter 37 for each MV output pulse
  • counter 37 counts up to its maximum value of 16 for each MV output pulse and hence for each heartbeat cycle.
  • the binary-coded output lines QA-QD of counter 37 are connected to the inputs of a
  • the Y7 output line of decoder 39 is connected by way of an inverter circuit 40 to the "clear” or “reset” input of the counter 37 to ensure resetting of the counter 37 back to zero at the trailing edge of the activauon signal on the Y7 output line of decoder 39
  • a particular time delay value is selected by selecting a particular one of the 16 decoder output lines and observing when such output line becomes active This is accomplished by the use of two 8-to-l line multiplexers 41 and 42 which are used in combination to provide a 16-to-l line multiplexer.
  • the 16 output lines of the combined decoder 38-39 are individually connected to different ones of data input lines D0-D7 of multiplexer (MUX) 41 and data input lines D0-D7 of multiplexer (MUX) 42
  • One of the 16 multiplexer data input lines is selected by internal multiplexer decoding of a 4-bit address signal A, B, C, D which is supplied to selection control terminals A. B, C.
  • the ST (strobe) inputs are used to choose between the two multiplexers 41 and 42
  • the desired 4-bit address signal is established by means of a manually settable hexadecimal switch 43.
  • the operator of the FIG 1 apparatus manually sets the switches in the hexadecimal switch 43 to provide the appropriate coding for selecting the desired one of the 16 possible multiplexer data input lines
  • the output lines W of the multiplexers 41 and 42 are connected to the two inputs of an OR gate 44
  • the output of OR gate 44 is in turn connected to a trigger input of a monostable multivibrator 45.
  • the leading edge of the multiplexer output pulse appearing on the output line of OR gate 44 causes a triggering of the multivibrator (MV) 45
  • the time duration of each pulse produced by the multivibrator 45 is determined by an adjustable resistor 46 and a capacitor 47 connected to the time constant inputs of the multivibrator 45 Adjustment of the resistor 46 sets the duration of the multivibrator 45 output pulses to have a value in the range of 1 to 50 milliseconds.
  • the output pulses produced by multivibrator 45 appear on output line 48 and occur at a selected time delay relative to the detector output pulses of detector 20.
  • the time delay circuitry of FIG. 2 is responsive to the detector output pulses from detector 20 for producing delayed pulses each having a selected time delay relative to its detector pulse.
  • the reoccurring bursts of energy supplied to the human body 10 for stimulating the body need not occur at precisely the same moment as the peak value in the heartbeat signal.
  • the burst of stimulation energy can be made to occur at any desired point during each heartbeat cycle. In other words, there will be one stimulation burst for each heartbeat cycle, but such burst need not occur at the peak point of the heartbeat cycle. It can be delayed by the time delay circuitry 27 to occur at any selected point during the heartbeat cycle.
  • the frequency of occurrence of the stimulating bursts remains the same as the frequency or rate of the human heartbeat being sensed.
  • the first portion of the time delay circuitry 27, which portion includes units 31-44 of FIG. 2 provides a coarse type of time delay which is adjustable in 50 millisecond steps by changing the setting of the switches in the hexadecimal switch unit 43.
  • the last portion of the time delay circuitry 27. which portion is represented by the multivibrator 45. provides a fine type of time delay adjustment which is added to the coarse time delay value selected by the hexadecimal switch 43. By adjusting the resistance value of the resistor 46, this added time delay increment can be varied over the range of 0 to 50 milliseconds, which 50 millisecond range corresponds to the time difference between successive coarse delay values selectable by switch 43.
  • time duration circuitry 28 is responsive to the delayed pulses produced by the time circuitry 27 for controlling the activation of the particular stimulating mechanism which is being used.
  • the delayed pulses from time delay circuitry 27 appear on line 48
  • the time duration circuitry 28 responds to these pulses to produce the control pulses or control signal bursts which are supplied to the stimulating mechanism
  • the time duration circuitry 28 includes circuitry for setting the time duration of these control pulses or control signal bursts
  • the delayed pulses on line 48 are supplied to a trigger input of a further monostable multivibrator 50
  • Each delayed pulse on line 48 triggers the multivibrator 50 to produce on the multivibrator output line 51 a pulse having the desired stimulation time duration.
  • This time duration is determined by the resistance value of adjustable resistor 52 and the capacitance value of the capacitor 53 which are connected to the time constant inputs of the multivibrator 50. By adjustment of the resistor 52. this time duration can be varied over a range of 1 to 10 milliseconds or longer.
  • Multivibrator 50 is t ⁇ ggered by the trailing edge of each delayed pulse appearing on the input line 48
  • the time duration controlling pulses appearing on output line 51 of multivibrator 50 are supplied to a first input of an AND gate 54.
  • Supplied to a second input of the AND gate 54 are oscillator signals produced by an oscillator circuit 55.
  • the frequency of oscillation ot the oscillator 55 is adjustable over a range of.
  • the AND gate 54 is enabled to pass the oscillator signal from oscillator 55 to an AND gate output line 54a During the absence of a duration control pulse on line 51 , this line 51 is at a low level and the output of AND gate 54 is disabled and no oscillator signals are supplied to the output
  • FIG. 3 also shows a representative form of construction for stimulating mechanism circuitry that can be used for stimulation units 14.
  • this stimulation mechanism circuitry is represented at 49 and includes an amplifier circuit 56 ing a transistor 57
  • the base electrode of transistor 57 is connected to a potentiometer 58 which receives the oscillator signal bursts from the AND gate 54 by way of a resistor 59 Potentiometer 58 is used to control the amplitude of the signal supplied to the body stimulator electrodes.
  • the output circuit for amplifier 56 includes a step-up transformer 60.
  • Amplifier output terminals 62 and 63 are, in turn, connected to the cable 17 (shown in FIG 1 ) which runs to the human body 10.
  • cable 17 is connected to the electrodes which are placed in contact with the human body 10
  • cable 17 is connected to the acupuncture needle or needles inserted into the human body and a current return electrode which contacts the body
  • a first choice is to omit the functions ot oscillator 55 and amplifier 56 and, instead, to supply the duration control pulses on multivibrator output line 51 directly to the input of the particular stimulation unit 1 1. 14. 15 or 16 which is to be used, this being done by way of the connector cable 64 shown in FIG 1. In some cases, the pulses on multivibrator output line 51 may be applied directh to the cable 17 which runs to the human body 10
  • oscillator 55 Another choice is to use the oscillator 55 and to supply the oscillator signal bursts on AND gate output line 54a directly to either the input of the stimulation unit or to the cable 17 which runs to the human body 10
  • the oscillator signal bursts on line 54a may be applied to the input of sound generator 11 by way of connector cable 64
  • a further choice is to use the amplifier circuitry 56 of FIG 3 and to connect the output terminals 62 and 63 directly to the cable 17 which runs to the human body 10 This would be particularly useful for the case of acupuncture needles where the acupuncture practitioner has no special equipment, other than his acupuncture needles
  • the graph of FIG 4 represents a portion of an electrocardiogram It shows a complete heartbeat cycle extending from a first R wave peak to the succeeding R wave peak.
  • this peak-to-peak time interval is 0.89 seconds, which corresponds to a heart rate of 67 4 beats per minute
  • the heartbeat cycle is composed of two major phases, namely, the systole phase and the diastole phase
  • the systole phase is the contraction phase
  • the diastole phase is the relaxation part of the cycle.
  • the heart muscles associated with the ⁇ ght and left ventricles are contracting to cause a corresponding contraction of the right and left ventricles
  • Contraction of the right ventricle forces blood through the pulmonary arteries and into the capillaries of the lung
  • Contraction of the left ventricle forces blood into the aorta and from there to all of the other arteries of the body
  • the diastole phase the heart muscles relax and the blood returning by way of the veins is allowed to flow into the ⁇ ght and left ventricles.
  • the rhythmatic contraction and relaxation of the heart muscles produce the rhythmatic fluctuations m the blood pressure which are sensed when measuring the pulse rate of a person.
  • the rhythmatic beating of the heart is maintained by an orderly series of elect ⁇ cal current discharges ongmating in the sinus node of the right at ⁇ um and proceeding through the at ⁇ oventricular node to the neuromuscular fibers making up the heart muscles.
  • a record of this current can be obtained.
  • This record is called an electrocardiogram and a portion of one such record is represented in FIG. 4.
  • the large peaks occurring at the beginning of the systole phases in the electrocardiogram are commonly refe ⁇ ed to as the R waves.
  • these R waves are detected by the detector circuitry 20 of FIG. 1.
  • the threshold setting potentiometer 24 for the voltage comparator 21 is set so that only the ups of the R waves are effective to produce the detector pulses appearing on detector circuit output line 30. This amplitude disc ⁇ minauon prevents other parts of the electrocardiogram signal from producing detector output pulses.
  • FIG. 5 shows some of the signals produced in the time duration circuitry 28 of FIG. 3.
  • Waveform 70 shows some of the pulses produced on the output line 51 of the duration control multivibrator 50. Relative to the electrocardiogram of FIG. 4, the leading edges of these time duration control pulses of waveform 70 occur at desired points in time relative to the peaks of the R waves. The time interval between the occu ⁇ ence of the R wave peak and the leading edge of the time duration control pulse of waveform 70 is equal to the time delay provided by the time delay circuitry 27 of FIG. 2. Since this time delay is adjustable, the leading edges of the waveform 70 pulses may be cause to occur at any desired point within the period of the heartbeat cycle.
  • the time of occurrence of the trailing edges of the time duration control pulses of waveform 70 is determined by the RC time constant for the multivibrator 50 and. more particularly, by the setting of the resistance value of the adjustable resistor 52. As indicated in FIG. 5, the time of occu ⁇ ence of this trailing edge is adjustable to provide the desired duration for the energy burst which is supplied to the stimulating mechanism.
  • Waveform 71 of FIG. 5 shows the signal appearing on the output line 54a of the AND gate 54 of FIG. 3.
  • the signal bursts shown in waveform 71 have the same time duration as the time duration control pulses of waveform 70.
  • the fluctuations in each signal burst shown in waveform 71 have a frequency determined by the oscillator 55 of FIG. 3 In the present example, this frequency is in the range of 5 kilohertz to 20 kilohertz
  • the signal bursts represented by waveform 71 are amplified in the amplifier circuit
  • the signal bursts of waveform 71 are supplied by way of cable 17 to the acupuncture needle or needles which are inserted into the human body 10.
  • the stimulation of the human body is harmonized with the natural rhythm of the human heart.
  • This pulsed application produces a noticeable improvement in the results of the body stimulation, as compared to the case where the electrical energy is applied in a continuous manner. It is like the case of pushing a child in a swing. The results are much better when the swing is pushed in an intermittent manner in rhythm with the natural back-and-forth pe ⁇ od of the swing.
  • va ⁇ ous circuits shown in FIGS. 1-3 may, for the most part, be provided by the use of commercially available integrated circuit modules. Representative integrated circuit modules which may be used are listed in the following table:

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Abstract

Cette invention décrit des procédés et un appareil afin d'améliorer le bien-être du corps humain (10). En ce qui concerne l'appareil, celui-ci comprend un mécanisme de stimulation (11, 14-16) qui stimule le corps humain au moyen d'impulsions d'énergie répétés. L'appareil comprend également un mécanisme de détection (18, 20) qui perçoit la pulsation cardiaque du corps humain, et un mécanisme de synchronisation couplé au mécanisme de stimulation, ainsi qu'au mécanisme de détection, afin de synchroniser la stimulation avec la pulsation cardiaque du corps humain en envoyant les impulsions d'énergie au même rythme que celui de la pulsation cardiaque du corps humain. Le mécanisme de synchronisation comprend des circuits réglables à action différée (27) afin de provoquer les impulsions d'énergie consécutives au même moment respectif dans des cycles de pulsation cardiaque consécutifs, tel moment étant réglable de telle manière à ce qu'il se produise en une position prédéterminée dans le cycle de pulsation cardiaque.
PCT/US1997/014663 1996-08-01 1997-07-31 Appareil et procede de guerison et d'amelioration du bien-etre du corps humain WO1998005379A1 (fr)

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US08/691,093 1996-08-01

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Cited By (11)

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EP1078649A1 (fr) * 1999-08-20 2001-02-28 CardioRest Ltd. Dispositif de traitement d'un organisme vivant pour réduire la charge cardiaque
WO2002066112A1 (fr) * 2001-02-20 2002-08-29 Cardiorest Ltd. Appareil servant a traiter un organisme vivant pour parvenir a une reduction de la sollicitation cardiaque et procede permettant d'obtenir une reduction de la sollicitation cardiaque
WO2005044373A1 (fr) * 2003-11-07 2005-05-19 Coral Licensing International Ltd. Appareil d'electrotherapie a contre-impulsions pour traiter une personne ou un mammifere
FR2869808A1 (fr) * 2004-05-04 2005-11-11 Marc Pujo Appareil de stimulation neuro musculaire pour les jambes avec une frequence equivalente au rythme cardiaque
WO2008128270A2 (fr) 2007-04-20 2008-10-30 Jozsef Constantin Szeles Appareil de stimulation ponctuelle
US7777622B2 (en) 2004-11-12 2010-08-17 Koninklijke Philips Electronics N.V. Message integrity for secure communication of wireless medical devices
CN103127612A (zh) * 2013-03-04 2013-06-05 任国祚 危重病人止痛仪
CN103432685A (zh) * 2013-08-20 2013-12-11 任国祚 一种戒毒仪
WO2023175398A1 (fr) * 2022-03-15 2023-09-21 Imutec SAS Dispositif de stimulation magnétique et optique cardiologique
WO2024163005A1 (fr) 2023-01-30 2024-08-08 The Procter & Gamble Company Distributeur d'aérosol contenant une composition de laque à cheveux et un agent propulseur à base d'azote
EP3256204B1 (fr) * 2015-02-15 2024-12-11 Ziv Healthcare Ltd. Système pour améliorer la variabilité de la fréquence cardiaque

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EP1541193B1 (fr) 2002-08-05 2015-11-18 National Cerebral and Cardiovascular Center Systeme de traitement medical utilisant une fonction regulatrice biologique, systeme de stimulateur cardiaque fonde sur ce systeme de traitement medical, systeme de regulation de pression sanguine et systeme de traitement de cardiopathie
CN106552319A (zh) * 2015-09-28 2017-04-05 赵信荣 电疗机改良结构及其控制方法
CN111035554A (zh) * 2019-12-30 2020-04-21 上海开司绫纺织科技有限公司 一种基于心跳同步的医学理疗方法
CN111939423B (zh) * 2020-06-29 2022-07-12 杨铭轲 基于自体心跳节奏的入睡引导方法、装置和计算机设备
CN118011932B (zh) * 2024-02-26 2024-10-15 重庆宁来科贸有限公司 一种选择确定式控制电路

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1078649A1 (fr) * 1999-08-20 2001-02-28 CardioRest Ltd. Dispositif de traitement d'un organisme vivant pour réduire la charge cardiaque
WO2001013990A1 (fr) * 1999-08-20 2001-03-01 Cardiorest International Ltd. Procede de traitement d'un organisme vivant pour obtenir une baisse du travail cardiaque, et dispositif servant a mettre en oeuvre ledit procede
US6450942B1 (en) 1999-08-20 2002-09-17 Cardiorest International Ltd. Method for reducing heart loads in mammals
US6832982B1 (en) 1999-08-20 2004-12-21 Coral Licensing International Ltd. Method of treating a living organism to achieve a heart load reduction, and apparatus for carrying out the method
US20070198064A1 (en) * 1999-08-20 2007-08-23 Cardiola Ltd. Counter pulsation electrotherapy apparatus for treating a person or a mammal
US8032207B2 (en) 1999-08-20 2011-10-04 Cardiola Ltd. Counter pulsation electrotherapy apparatus for treating a person or a mammal
WO2002066112A1 (fr) * 2001-02-20 2002-08-29 Cardiorest Ltd. Appareil servant a traiter un organisme vivant pour parvenir a une reduction de la sollicitation cardiaque et procede permettant d'obtenir une reduction de la sollicitation cardiaque
WO2005044373A1 (fr) * 2003-11-07 2005-05-19 Coral Licensing International Ltd. Appareil d'electrotherapie a contre-impulsions pour traiter une personne ou un mammifere
FR2869808A1 (fr) * 2004-05-04 2005-11-11 Marc Pujo Appareil de stimulation neuro musculaire pour les jambes avec une frequence equivalente au rythme cardiaque
US7777622B2 (en) 2004-11-12 2010-08-17 Koninklijke Philips Electronics N.V. Message integrity for secure communication of wireless medical devices
WO2008128270A3 (fr) * 2007-04-20 2009-02-12 Jozsef Constantin Szeles Appareil de stimulation ponctuelle
WO2008128270A2 (fr) 2007-04-20 2008-10-30 Jozsef Constantin Szeles Appareil de stimulation ponctuelle
US8175699B2 (en) 2007-04-20 2012-05-08 Jozsef Constantin Szeles Punctual stimulation apparatus
CN101678206B (zh) * 2007-04-20 2014-09-10 约瑟夫·康斯坦丁·塞勒斯 单点刺激设备
CN103127612A (zh) * 2013-03-04 2013-06-05 任国祚 危重病人止痛仪
CN103432685A (zh) * 2013-08-20 2013-12-11 任国祚 一种戒毒仪
EP3256204B1 (fr) * 2015-02-15 2024-12-11 Ziv Healthcare Ltd. Système pour améliorer la variabilité de la fréquence cardiaque
WO2023175398A1 (fr) * 2022-03-15 2023-09-21 Imutec SAS Dispositif de stimulation magnétique et optique cardiologique
MA67284A1 (fr) * 2022-03-15 2025-02-28 Imutec SAS Dispositif de stimulation magnétique et optique cardiologique
WO2024163005A1 (fr) 2023-01-30 2024-08-08 The Procter & Gamble Company Distributeur d'aérosol contenant une composition de laque à cheveux et un agent propulseur à base d'azote

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CN1207948A (zh) 1999-02-17
TW431898B (en) 2001-05-01

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